Also listed under Head & Neck Cancer, Thyroid Diseases
ClinicalTrials.gov term: Thyroid Neoplasms
Thyroid Cancer clinical trials
Data updated daily from ClinicalTrials.gov, last refresh 2026-11-14
What changed in the last 30 days
28 trials changed in the last 30 days: 2 stopped, 8 with notable changes, 18 with minor changes only.
- Minor: BCB RIV · Clinico-biological Database in Patients Treated With Metabolic Radiotherapy in the Nuclear Medicine Department Study completion pushed from Oct 2029 to Oct 2036
- Minor: FNA inadequacy · Factors Influencing Inadequacy in Rapid Onsite Evaluation of Ultrasound Guided Fine Needle Aspiration (FNA) Samples of Thyroid Nodules Trial completed
- Minor: Application of Electrical Stimulation in Postoperative Pain Management of Thyroid Surgery Interventions modified
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Minor: 8 trials marked Unknown by the registry's verification sweep Changed
- Minor: JK08 · Unresectable Locally Advanced or Metastatic Cancer Changed Registry marked status Unknown (sponsor has not verified the record since Oct 2024); last known: Active, Not Recruiting
- Minor: QUANTUM · Quest to Analyze One Thousand Humans Meditating Changed Registry marked status Unknown (sponsor has not verified the record since Oct 2024); last known: Enrolling by Invitation
- Minor: Restor. I-131 Upt. + Selpercatinib in RET F-P RAI-R TC Changed Registry marked status Unknown (sponsor has not verified the record since Oct 2024); last known: Recruiting
- Minor: Treatment of Differentiated Thyroid Carcinoma with Anlotinib Changed Registry marked status Unknown (sponsor has not verified the record since Oct 2024); last known: Active, Not Recruiting
- Minor: Dual-targeting Tracer TATE-RGD for the Diagnosis of SSTR- and RGD- Positive Tumors Changed Registry marked status Unknown (sponsor has not verified the record since Oct 2024); last known: Recruiting
- Minor: EMIRATES Study Changed Registry marked status Unknown (sponsor has not verified the record since Oct 2024); last known: Recruiting
- Minor: Prevalence of Osteo-metabolic Complications · Thyroid Cancer Changed Registry marked status Unknown (sponsor has not verified the record since Oct 2024); last known: Recruiting
- Minor: Cognition and QoL After Thyroid Surgery Changed Registry marked status Unknown (sponsor has not verified the record since Jan 2023); last known: Recruiting
- Minor: PURE · Nasal Steam Therapy for Post-extubation Respiratory Events Trial completed
- Notable: Bevacizumab and Temsirolimus Alone or in Combination With Valproic Acid or Cetuximab · Advanced or Metastatic Malignancy or Other Benign Disease Results posted: Nov 5, 2026
- Minor: DNA Methylation Signatures for the Diagnosis and Management of Thyroid Nodules Primary and study completion pushed from Oct 22, 2026 to Jan 21, 2027
- Notable: CAMPERR · CfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease Primary completion pushed from Mar 2026 to Dec 31, 2026
- Notable: ACC-1898 · Advanced Solid Tumors Primary completion pushed from Jun 2027 to Jun 2028
- Notable: Trametinib in Combination With Paclitaxel · Anaplastic Thyroid Cancer Primary and study completion pushed from Sep 2026 to Sep 2027
- Notable: REPOTHYROID-II · Drug Repurposing in Thyroid Carcinoma: a Feasibility Trial Enrollment reopened
- Notable: PPB/DICER1 Registry Primary completion pushed from Dec 6, 2030 to Dec 6, 2031
- Stopped: Personalized Treatment in Thyroid Disorders Recruitment suspended
- Notable: Larotrectinib to Enhance RAI Avidity in Differentiated Thyroid Cancer Primary completion pushed from Oct 1, 2026 to Oct 1, 2028
- Minor: Cabozantinib Compared With Placebo · Radioiodine-refractory Differentiated Thyroid Cancer Who Have Progressed After Prior Vascular Endothelial Growth Factor Receptor (VEGFR) -Targeted Therapy Study completion pushed from Jul 31, 2026 to Jul 31, 2027
- Minor: Biodistribution of an Imaging Tracer (68Ga-FAPi-46) · Solid Tumors or Hematologic Cancers Primary completion date changed from estimate of Sep 6, 2026 to Jun 23, 2026
- Notable: STAGE-MTC Trial Thyroid Lobectomy With Ipsilateral Central Neck Dissection Primary completion pushed from Sep 2, 2031 to Sep 2, 2032
- Stopped: Dabrafenib, Trametinib, and IMRT · BRAF Mutated Anaplastic Thyroid Cancer Recruitment suspended
- Minor: Real-World Study of Second-line Therapies Among Radioiodine-refractory Differentiated Thyroid Cancer (RAI-R DTC) Patients Primary and study completion pushed from Oct 31, 2026 to Jan 5, 2027
- Minor: MDX2001 · Advanced Solid Tumors Enrollment increased: 285 → 330 participants
- Stopped: terminated, suspended or withdrawn
- Notable: the plan changed
- Minor: routine updates
New sponsor entrants, last 90 days sponsors with their first trial in this area
| First posted | Trial | Sponsor | Phase |
|---|---|---|---|
| 2026-11-03 | NCT07911761 Prophylactic Central Neck Dissection for Papillary Thyroid Carcinoma | Mansoura University new | |
| 2026-11-03 | NCT07911891 Oral Mecobalamin for TKI-Associated Hand-Foot Syndrome in Advanced Thyroid Cancer | Li Zhihui new | Phase 2 |
| 2026-09-10 | NCT07812779 Thyroid Health Outcomes Registry for Surgery | Pirogov Russian National Research Medical University new | |
| 2026-08-20 | NCT07776262 Safety and Efficacy of Cryoablation for Thyroid Tumors | Yukun Luo new |
Active trials by phase
| Early Phase 1 | 5 | |
| Phase 1 | 27 | |
| Phase 1/2 | 13 | |
| Phase 2 | 64 | |
| Phase 2/3 | 5 | |
| Phase 3 | 17 | |
| Phase 4 | 8 |
Not charted: 188 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).
Top sponsors by active trials in this area
M.D. Anderson Cancer Center (17) · Memorial Sloan Kettering Cancer Center (14) · National Cancer Institute (NCI) (11) · Fudan University (10) · Fujian Medical University (7) · West China Hospital (7) · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University (6) · Cancer Institute and Hospital, Chinese Academy of Medical Sciences (5) · Eli Lilly and Company (5) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (5)
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