The Effect of Light Therapy on Cellular Energy and Oxidative Stress in Healthy Adults and Type 1 Diabetic Patients

Study acronym: PBM-T1D
StatusNot Yet Recruiting
PhaseNot applicable
Started

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Record History

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  1. Minor Start date pushed from Oct 1, 2026 to Oct 13, 2026
  2. Minor Study site revised
  3. Minor Study sites: 0 to 1
    • Eligibility criteria expanded, about 28 words
    • Study description expanded, about 196 words
  4. Minor Study First Submitted
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The goal of this clinical trial is to evaluate the effects of low-level light therapy on cellular energy and oxidative stress in healthy adults and patients with Type 1 diabetes. The main questions it aims to answer are: Does light therapy change adenosine triphosphate (ATP) levels and cytochrome c oxidase activity in blood cells? How does the intervention affect oxidative stress markers, specifically glutathione and malondialdehyde concentrations? Researchers will compare blood samples collected before the light therapy to those collected afterward to see if the intervention alters mitochondrial function. Researchers will also compare the responses of healthy volunteers to those of diabetic patients. Participants will: Provide a baseline blood sample. Receive red and near-infrared light exposure (660 nm and 850 nm) on their arms for 10 to 20 minutes using a therapy pad. Provide a final blood sample immediately after the light exposure.
Trial Details
NCT Number NCT07833865
Lead Sponsor University of Thi-Qar
Conditions
(from sponsor)
Healthy, Diabetes Mellitus Type 1
Related terms Diabetes Mellitus, Type 1
Enrollment 30 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov