London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's clinical trial pipeline

18 trials changed in the last 30 days: 1 stopped, 14 with notable changes, 3 with minor changes only.

1. Stopped

   Cytokine Alterations and Chronic Post-Surgical Pain

   Withdrawn before enrolling

   London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's·Not specified· NCT06418295· Registry history of NCT06418295 on ClinicalTrials.gov (opens the registry)

   Sep 22, 2026

2. Notable

   Preservation of Swallowing in Respected Oral Cavity Squamous Cell…Preservation of Swallowing in Respected Oral Cavity Squamous Cell Carcinoma: Examining Radiation Volume Effects (PRESERVE): A Randomized Trial

   Primary and study completion pushed from Sep 2026 to Sep 2027

   Also in this update: Trial status changed: Unknown → Active, Not Recruiting; and 1 more change in the last 30 days

   London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's·Phase 2· NCT03997643· Registry history of NCT03997643 on ClinicalTrials.gov (opens the registry)

   Oct 5, 2026

3. Notable

   HOPE · Hypofractionated Whole-Pelvis Radiotherapy (WPRT) vs…HOPE · Hypofractionated Whole-Pelvis Radiotherapy (WPRT) vs Conventionally-Fractionated WPRT in Prostate Cancer

   Primary completion pushed from Sep 2026 to Sep 2027

   Also in this update: Study completion pushed from Mar 2027 to Mar 2028

   London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's·Phase 2· NCT04197141· Registry history of NCT04197141 on ClinicalTrials.gov (opens the registry)

   Oct 1, 2026

4. Notable

   Extracorporeal Photopheresis in Early Diffuse Cutaneous Systemic…Extracorporeal Photopheresis in Early Diffuse Cutaneous Systemic Sclerosis

   Primary completion pushed from Jul 2026 to Jul 2028

   Also in this update: Recruitment opened; Study completion pushed from Jul 2027 to Jul 2029

   London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's·Phase 2· NCT04986605· Registry history of NCT04986605 on ClinicalTrials.gov (opens the registry)

   Oct 1, 2026

5. Notable

   M3-JIA · Making Mindfulness Matter · JIA

   Primary completion pushed from Dec 2025 to Jul 2027

   Also in this update: Study completion pushed from Feb 2026 to Sep 2027

   London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's·Not applicable· NCT06376149· Registry history of NCT06376149 on ClinicalTrials.gov (opens the registry)

   Oct 9, 2026

6. Notable

   DIALEX · DIALysis With EXpanded Solute Removal

   Primary and study completion pushed from Aug 2030 to Apr 2031

   London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's·Not applicable· NCT06660277· Registry history of NCT06660277 on ClinicalTrials.gov (opens the registry)

   Sep 24, 2026

7. Notable

   NitrX Total Knee Arthroplasty RSA

   Primary completion pushed from Dec 31, 2025 to Feb 2027

   Also in this update: Study completion pushed from Feb 28, 2026 to Feb 2027

   London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's·Not applicable· NCT05151315· Registry history of NCT05151315 on ClinicalTrials.gov (opens the registry)

   Sep 22, 2026

8. Notable

   Role of Synovectomy in Pain Reduction Following Total Knee…Role of Synovectomy in Pain Reduction Following Total Knee Arthroplasty

   Primary completion pushed from Dec 2025 to Dec 2027

   Also in this update: Study completion pushed from Dec 2026 to Dec 2027

   London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's·Not applicable· NCT05800457· Registry history of NCT05800457 on ClinicalTrials.gov (opens the registry)

   Sep 22, 2026

9. Notable

   DDAVP Effect by TEG6 in Cardiac Surgery

   Primary completion pushed from Dec 1, 2027 to Dec 1, 2028

   Also in this update: Recruitment opened; Study completion pushed from Dec 31, 2027 to Dec 31, 2028

   London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's·Not specified· NCT07179991· Registry history of NCT07179991 on ClinicalTrials.gov (opens the registry)

   Sep 21, 2026

10. Notable

    SYN2 · SYNERGIC-2 Trial (SYNchronizing, Exercises and Remedies…SYN2 · SYNERGIC-2 Trial (SYNchronizing, Exercises and Remedies to GaIn Cognition@Home)

    Primary completion pushed from Nov 30, 2025 to Nov 30, 2027

    Also in this update: Study completion pushed from Dec 30, 2026 to Dec 30, 2028

    London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's·Not applicable· NCT05375513· Registry history of NCT05375513 on ClinicalTrials.gov (opens the registry)

    Sep 21, 2026

11. Notable

    Using ROSA for Challenging The TKA Standard of Care

    Primary and study completion pushed from Dec 2025 to Dec 2028

    Also in this update: Phase changed: Phase 4 → not applicable

    London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's·Not applicable· NCT06267482· Registry history of NCT06267482 on ClinicalTrials.gov (opens the registry)

    Sep 21, 2026

12. Notable

    GUMBO · Gut Microbiome in Orthopaedics: Revision Total Knee…GUMBO · Gut Microbiome in Orthopaedics: Revision Total Knee Arthroplasty

    Recruitment opened

    London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's·Not specified· NCT06951477· Registry history of NCT06951477 on ClinicalTrials.gov (opens the registry)

    Sep 22, 2026

13. Notable

    Suprazygomatic Maxillary Nerve Block in Pediatric Tonsillectomy

    Recruitment opened

    Also in this update: Primary completion moved earlier from Dec 31, 2027 to Jun 30, 2027

    London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's·Not applicable· NCT07176533· Registry history of NCT07176533 on ClinicalTrials.gov (opens the registry)

    Sep 22, 2026

14. Notable

    Olfactory Outcomes of Dupilumab Treatment for Nasal Polyposis

    Primary completion date changed from estimate of Sep 1, 2025 to Sep 1, 2026

    Also in this update: Trial completed; Final enrollment: 15 participants (planned 27)

    London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's·Phase 4· NCT04869436· Registry history of NCT04869436 on ClinicalTrials.gov (opens the registry)

    Sep 22, 2026

15. Notable

    Pre-Op THA Modelling

    Enrollment increased: 80 → 180 participants

    Also in this update: Interventions modified; Trial arms changed: 2 → 3; and 2 more changes in the last 30 days

    London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's·Not applicable· NCT05221554· Registry history of NCT05221554 on ClinicalTrials.gov (opens the registry)

    Oct 7, 2026

• Stopped: an ongoing trial was terminated, suspended or withdrawn.
• Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
• Minor: routine progress and housekeeping, such as sites added or enrollment closed.