Washington University School of Medicine clinical trial pipeline

29 trials changed in the last 30 days: 3 stopped, 13 with notable changes, 13 with minor changes only.

1. Stopped

   64Cu-LLP2A for Imaging Hematologic Malignancies

   Trial terminated

   Also in this update: Final enrollment: 21 participants (planned 42); Primary completion date changed from estimate of Mar 31, 2027 to Aug 28, 2026

   Washington University School of Medicine·Early Phase 1· NCT06636175· Registry history of NCT06636175 on ClinicalTrials.gov (opens the registry)

   Oct 8, 2026

2. Stopped

   Memory-Like Natural Killer Cells With Nivolumab and Relatlimab in…Memory-Like Natural Killer Cells With Nivolumab and Relatlimab in Advanced or Metastatic Melanoma After Progression on Checkpoint Inhibitors

   Recruitment suspended

   Washington University School of Medicine·Phase 1· NCT05629546· Registry history of NCT05629546 on ClinicalTrials.gov (opens the registry)

   Sep 22, 2026

3. Stopped

   Proton Beam Therapy · Esophageal Cancer

   Trial terminated

   Also in this update: Study completion date changed from estimate of Aug 9, 2026 to Sep 9, 2026

   Washington University School of Medicine·Not applicable· NCT03482791· Registry history of NCT03482791 on ClinicalTrials.gov (opens the registry)

   Oct 2, 2026

4. Notable

   Palbociclib and Cetuximab Versus Cetuximab Monotherapy…Palbociclib and Cetuximab Versus Cetuximab Monotherapy · CDKN2A-altered, HPV-unrelated Head and Neck Squamous Cell Carcinoma Who Experienced Disease Progression on a PD-1/L1 Inhibitor

   Primary and study completion pushed from Feb 28, 2028 to Feb 28, 2029

   Washington University School of Medicine·Phase 3· NCT04966481· Registry history of NCT04966481 on ClinicalTrials.gov (opens the registry)

   Sep 22, 2026

5. Notable

   BettER · Biomarker Driven Early Therapeutic Selection · HR+…BettER · Biomarker Driven Early Therapeutic Selection · HR+ HER2- Metastatic or Unresectable Breast Cancer

   Primary and study completion pushed from Sep 30, 2034 to Sep 30, 2035

   Also in this update: Primary endpoint(s) modified; Enrollment increased: 65 → 145 participants

   Washington University School of Medicine·Not applicable· NCT05977036· Registry history of NCT05977036 on ClinicalTrials.gov (opens the registry)

   Oct 9, 2026

6. Notable

   DIAN · Dominantly Inherited Alzheimer Network (DIAN)

   Primary and study completion pushed from Sep 2026 to Sep 2031

   Washington University School of Medicine·Not specified· NCT00869817· Registry history of NCT00869817 on ClinicalTrials.gov (opens the registry)

   Oct 5, 2026

7. Notable

   HTN2 · Hypertension Treatment in Nigeria: Hypertension Diabetes…HTN2 · Hypertension Treatment in Nigeria: Hypertension Diabetes Integration Study- Formative Aim 3

   Primary endpoint(s) modified

   Also in this update: Recruitment opened; Trial sites expanded: 0 → 10 locations

   Washington University School of Medicine·Not applicable· NCT07589387· Registry history of NCT07589387 on ClinicalTrials.gov (opens the registry)

   Oct 16, 2026

8. Notable

   Whole Genome Sequencing (ChromoSeq) as an Adjunct to Conventional…Whole Genome Sequencing (ChromoSeq) as an Adjunct to Conventional Genomic Profiling in MDS

   Primary endpoint(s) modified

   Also in this update: Enrollment increased: 60 → 100 participants; Trial arms changed: 2 → 3

   Washington University School of Medicine·Not applicable· NCT05434598· Registry history of NCT05434598 on ClinicalTrials.gov (opens the registry)

   Oct 13, 2026

9. Notable

   TRIDENT · RANKL Inhibition and Mammographic Breast Density

   Primary endpoint(s) modified

   Also in this update: Results posted: Oct 9, 2026; Study completion pushed from Aug 31, 2026 to Sep 30, 2027

   Washington University School of Medicine·Phase 2· NCT04067726· Registry history of NCT04067726 on ClinicalTrials.gov (opens the registry)

   Oct 9, 2026

10. Notable

    RESTORE Declined Livers Study

    Primary endpoint(s) modified

    Also in this update: Results posted: Sep 23, 2026; Trial completed

    Washington University School of Medicine·Not applicable· NCT04483102· Registry history of NCT04483102 on ClinicalTrials.gov (opens the registry)

    Sep 23, 2026

11. Notable

    PRIME-KS · Precision Imaging to Evaluate Kaposi Sarcoma

    Enrollment reduced: 300 → 180 participants

    Washington University School of Medicine·Not applicable· NCT06898203· Registry history of NCT06898203 on ClinicalTrials.gov (opens the registry)

    Sep 21, 2026

12. Notable

    HTN 2 · Hypertension Treatment in Nigeria 2.0

    Recruitment opened

    Also in this update: Trial sites expanded: 0 → 49 locations

    Washington University School of Medicine·Not applicable· NCT07351162· Registry history of NCT07351162 on ClinicalTrials.gov (opens the registry)

    Oct 14, 2026

13. Notable

    CCR2 PET Imaging Head and Neck Squamous Cell Carcinoma

    Recruitment opened

    Also in this update: Primary and study completion pushed from Mar 31, 2032 to May 31, 2032

    Washington University School of Medicine·Phase 2· NCT07659678· Registry history of NCT07659678 on ClinicalTrials.gov (opens the registry)

    Oct 7, 2026

14. Notable

    Whole Genome Sequencing (ChromoSeq®) for Acute Lymphoblastic…Whole Genome Sequencing (ChromoSeq®) for Acute Lymphoblastic Leukemia (ALL) Patients

    Recruitment resumed after suspension

    Also in this update: Interventions modified

    Washington University School of Medicine·Not specified· NCT07313592· Registry history of NCT07313592 on ClinicalTrials.gov (opens the registry)

    Oct 9, 2026

15. Notable

    Indocyanine Green With Near Infrared Imaging for Intraoperative…Indocyanine Green With Near Infrared Imaging for Intraoperative Visualization of Head and Neck Squamous Cell Carcinoma

    Recruitment opened

    Also in this update: Primary and study completion moved earlier from Apr 30, 2028 to Mar 31, 2028; Start date changed from estimate of Oct 31, 2026 to Sep 30, 2026

    Washington University School of Medicine·Not specified· NCT07825597· Registry history of NCT07825597 on ClinicalTrials.gov (opens the registry)

    Oct 9, 2026

16. Notable

    Using Personalized Rehabilitation to Reduce Disease and Increase…Using Personalized Rehabilitation to Reduce Disease and Increase Activity · Polymyalgia Rheumatica

    Recruitment opened

    Washington University School of Medicine·Not applicable· NCT07749547· Registry history of NCT07749547 on ClinicalTrials.gov (opens the registry)

    Oct 7, 2026

• Stopped: an ongoing trial was terminated, suspended or withdrawn.
• Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
• Minor: routine progress and housekeeping, such as sites added or enrollment closed.