Dominantly Inherited Alzheimer Network (DIAN)

Study acronym: DIAN
StatusRecruiting
PhaseNot specified
Started

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Trial flagged as At Risk
Primary completion moved at least 4 years 11 months later Sep 2026 → Sep 2031
See other at-risk trials from Washington University School of Medicine

Record History

See every version on ClinicalTrials.gov ↗

  1. Primary and study completion pushed from Sep 2026 to Sep 2031
  2. Eligibility criteria expanded, about 9 words
    • Study description expanded, about 10 words
    • Site details revised at 4 of 26 sites
    • Publications: details revised at 9 of 9 entries
  3. Primary and study completion moved earlier from Jul 2027 to Sep 2026v43
  4. Primary and study completion pushed from Jul 2026 to Jul 2027v42
  5. Site details revised at 9 of 26 sitesv41
Show 39 earlier versionsHide 39 earlier versions
  1. Primary completion date: Jul 2025 to Jul 2026
    • Study sites: 25 to 26
    v40
  2. Study completion date: Jul 2025 to Jul 2026
    • Site details revised at 5 of 25 sites
    v39
  3. Site details revised at 5 of 25 sitesv38
  4. Study sites: 24 to 25v37
  5. Primary and study completion dates: Jul 2024 to Jul 2025
    • Study sites: 23 to 24
    v36
  6. Eligibility criteria expanded, about 8 words
    • Study sites revised (23)
    v35
  7. Site details revised at 2 of 23 sitesv34
  8. Study sites: 20 to 23v33
  9. Study sites: 16 to 20
    • Study description expanded, about 66 words
    v32
  10. Primary and study completion dates: Jun 2019 to Jul 2024
    • Enrollment target: 600 to 700
    • Study sites revised (16)
    v31
  11. Site contacts updated at 3 of 16 sitesv30
  12. Enrollment target: 400 to 600v29
  13. Study sites: 15 to 16v28
  14. Site contacts updated at 1 of 15 sitesv27
  15. Site contacts updated at 1 of 15 sitesv26
  16. Study sites: 13 to 15
    • Eligibility criteria expanded, about 64 words
    • Study description expanded, about 84 words
    v25
  17. Study sites: 14 to 13v24
  18. Site contacts updated at 1 of 14 sitesv23
  19. Primary and study completion dates: Jun 2014 to Jun 2019
    • Site contacts updated at 1 of 14 sites
    v22
  20. Site contacts updated at 1 of 14 sitesv21
  21. Site contacts updated at 1 of 14 sitesv20
  22. Study sites: 13 to 14v19
  23. Re-verified, no change to tracked fieldsv18
  24. Site contacts updated at 3 of 13 sitesv17
  25. Study sites: 11 to 13v16
  26. Site contacts updated at 2 of 11 sitesv15
  27. Site contacts updated at 2 of 11 sitesv14
  28. Site details revised at 2 of 11 sites
    • Collaborators: 2 to 1
    v13
  29. Study sites: 10 to 11v12
  30. Site contacts updated at 1 of 10 sitesv11
  31. Site contacts updated at 1 of 10 sitesv10
  32. Study sites revised (10)v9
  33. Lead sponsor: National Institute on Aging (NIA) to Washington University School of Medicine
    • Collaborators: 1 to 2
    v8
  34. Site contacts updated at 1 of 10 sitesv7
  35. Site contacts updated at 2 of 10 sites
    • Collaborators expanded, about 1 word
    v6
  36. Site contacts updated at 1 of 10 sitesv5
  37. Collaborators shortened, about 1 wordv4
  38. Site contacts updated at 3 of 10 sitesv3
  39. Study description expanded, about 2 wordsv2
  1. Study First Submitted
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The purpose of this study is to identify potential biomarkers that may predict the development of Alzheimer's disease in people who carry an Alzheimer's mutation.
Trial Details
NCT Number NCT00869817
Lead Sponsor Washington University School of Medicine
Collaborators: National Institute on Aging (NIA)
Conditions
(from sponsor)		 Alzheimer's Disease
Related terms Alzheimer Disease, Alzheimer disease type 4, Alzheimer disease, familial, type 3
Enrollment 700 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov