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Washington University School of Medicine clinical trial pipeline

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363 active trials 209 recruiting 11 Phase 3 56 disease areas 88 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-09-05

What changed in the last 30 days showing 47 of 88 changes on 20 trials

2026-09-05
critical
Recruitment suspended
Recruitment suspended: Protocol amendment
NCT06968988 Zanzalintinib in Combination With Ipilimumab and Nivolumab in Patients With Metastatic… · Phase 1
2026-09-04
critical
Trial terminated
Trial terminated: Polaris decided to close to accrual.
NCT05813327 Neoadjuvant ADI-PEG 20 + Ifosfamide + Radiotherapy in Soft Tissue Sarcoma · Phase 1
2026-08-26
critical
Withdrawn before enrolling
Trial withdrawn: not a clinical trial
Enrollment reduced: 50 → 0 participants
NCT06562439 Testing the Sickle Cell Caregiver Collaboration for Child Development (SCCCD) Intervention
2026-08-08
critical
Trial status changed: Enrolling by Invitation → Terminated
Trial terminated: Funding discontinued
Enrollment reduced: 20 → 13 participants
Primary completion pushed: 2025-11 → 2025-12-03
Completion moved earlier: 2026-12 → 2025-12-03
NCT06061341 TruGraf Liver Gene Expression Serial Test
2026-09-04
notable
Primary completion pushed: 2032-10-07 → 2033-03-07
Completion pushed: 2032-10-07 → 2033-03-07
NCT05521997 Glutaminase Inhibition and Chemoradiation in Advanced Cervical Cancer · Phase 2
2026-09-03
critical
Primary completion pushed: 2025-04-30 → 2027-08-31
Completion pushed: 2026-04-30 → 2027-08-31
NCT06036524 Multi-modal Imaging of Myofascial Pain
2026-08-29
critical
Primary completion pushed: 2026-05-15 → 2026-09-30
Primary endpoint(s) modified
Completion pushed: 2026-05-15 → 2026-09-30
NCT02270814 Cisplatin, Nab-Paclitaxel, and Cetuximab (CACTUX) in Patients With Incurable Head and… · Phase 2
2026-08-29
critical
Primary completion pushed: 2027-07-31 → 2028-07-31
Completion pushed: 2029-07-31 → 2030-07-31
NCT06687772 CNS-Relapse Prevention in High-Risk Diffuse Large B-cell Lymphoma With Thiotepa-based… · Phase 2
2026-08-08
critical
Primary completion pushed: 2028-12-01 → 2029-04
Primary endpoint(s) modified
Trial sites expanded: 0 → 10 locations
Completion pushed: 2029-03-01 → 2029-04
NCT07569640 HFrEF Polypill in Sri Lanka RCT · Phase 3
2026-08-20
critical
Primary completion pushed: 2025-09-30 → 2027-09-30
Completion pushed: 2025-11-30 → 2028-11-30
NCT05111262 Symptom-driven ICS/LABA Therapy for Patients With Asthma Non-adherent to Daily… · Phase 1/2
2026-08-14
notable
Primary completion pushed: 2028-08-31 → 2028-11-30
Completion pushed: 2033-08-31 → 2033-11-30
NCT07552558 Ficerafusp Alfa, Pembrolizumab, and Stereotactic Body Radiotherapy (SBRT) for Head and… · Phase 1/2
2026-08-11
notable
Primary completion pushed: 2028-01-31 → 2028-05-31
Completion pushed: 2029-02-28 → 2029-06-30
NCT06240754 Enasidenib for Patients With Clonal Cytopenia of Undetermined Significance and Mutations… · Phase 2
2026-08-07
critical
Primary completion pushed: 2031-12-31 → 2032-06-30
Completion pushed: 2031-12-31 → 2032-06-30
NCT06483100 Measurable Residual Disease-Guided Post-Transplant Elranatamab Maintenance · Phase 2
2026-08-07
notable
Primary completion pushed: 2030-12-31 → 2031-04-30
Completion pushed: 2030-12-31 → 2031-04-30
NCT07101666 Total Neoadjuvant Therapy With Short Course Radiation Therapy in Gastric Cancer · Phase 2
2026-08-26
critical
Primary completion pushed: 2026-05 → 2027-05
Completion pushed: 2026-07 → 2027-07
NCT06168071 Transauricular Vagus Nerve Stimulation in Children
2026-08-20
critical
Primary completion pushed: 2026-03-31 → 2027-03-31
Enrollment closed, study ongoing
Completion pushed: 2026-03-31 → 2027-03-31
NCT04406818 Metabolic and Hemodynamic Reserve in Pediatric SCA
2026-08-13
critical
Primary completion pushed: 2026-08-31 → 2027-02-28
Completion pushed: 2026-08-31 → 2027-02-28
NCT07146568 Evaluating the Implementation and Effectiveness of the Pink and Pearl Campaign on Lung…
2026-08-13
notable
Primary completion pushed: 2027-12-31 → 2028-04-30
Completion pushed: 2027-12-31 → 2028-04-30
NCT07549139 Overcoming Racial Disparities in Screening Mammography
2026-08-11
critical
Primary completion pushed: 2026-03-31 → 2026-12-31
Completion pushed: 2026-07-01 → 2027-03-31
NCT06830096 Role of KATP Channel Loss in Type 2 Diabetes
2026-08-20
critical
Primary endpoint(s) modified
NCT07241117 CHEST: A Collaboration With Community HEalth Centers to Implement SmarT for Asthma · Phase 4

New trial filings, last 30 days

First postedTrialPhaseStatus
2026-09-02 NCT07800455 Amygdala-Prefrontal in Fear Extinction Recruiting
2026-09-02 NCT07800481 PET Imaging of Natriuretic Peptide Receptor C (NPR-C) in Carotid Atherosclerosis With… Early Phase 1 Recruiting
2026-08-24 NCT07781774 Improving Colorectal Cancer Screening Uptake Through Education and Stool-Based Testing… Not Yet Recruiting
2026-08-24 NCT07781800 Navigation Interventions for Patients With Breast Cancer and High-risk Social… Not Yet Recruiting
2026-08-20 NCT07776444 Cerebrovascular Reactivity Measurements With High-Density Diffuse Optical Tomography Recruiting
2026-08-20 NCT07776457 Substance Use in Pregnancy - Optimizing Retention in Treatment by Maximizing… Phase 2 Not Yet Recruiting
2026-08-20 NCT07777900 Glycated Albumin Monitoring Enrolling by Invitation
2026-08-18 NCT07771621 PET Imaging With [18F]Fluselenamyl in People With Cardiac Amyloidosis Phase 1 Enrolling by Invitation
2026-08-14 NCT07764432 Communication and Hospice Online With Optimal Support and Engagement Not Yet Recruiting
2026-08-11 NCT07758270 Brain Imaging and Immune Changes During Remibrutinib Treatment in Multiple Sclerosis. Recruiting

Active trials by phase

Early Phase 1
10
Phase 1
45
Phase 1/2
19
Phase 2
69
Phase 2/3
4
Phase 3
7
Phase 4
4
Not charted: 205 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 363

NCT IDTitleConditionStatusUpdated
Phase 4
NCT07241117 CHEST: A Collaboration With Community HEalth Centers to Implement SmarT for Asthma Moderate to Severe Asthma Recruiting 2026-08-19
NCT07177417 Characterizing the Human Airway Immune Response to FluMist Vaccination Healthy Young Adults Recruiting 2025-09-17
NCT07493460 Longitudinal Tracking of Bone Marrow Plasma Cell Responses to Licensed Human Vaccines Immunology Active, Not Recruiting 2026-07-01
NCT07280195 ZYNRELEF vs Continuous Catheter for Pain Management Following Shoulder Arthroplasty Total Shoulder Arthroplasty Enrolling by Invitation 2026-02-19
Phase 3
NCT07569640 HFrEF Polypill in Sri Lanka RCT Heart Failure With Reduced Ejection Fraction Recruiting 2026-08-28
NCT04966481 Palbociclib and Cetuximab Versus Cetuximab Monotherapy for Patients With CDKN2A-altered… HPV-unrelated Head and Neck Squamous Cell Carcinoma Recruiting 2026-05-19
NCT06969287 Mitigating Delirium With Fluvoxamine Treatment for Non-Cardiac Surgery Delirium Recruiting 2026-04-29
NCT05790252 Transdermal Patch for BupRenorphine Induction DurinG PrEgnancy (Patch BRIDGE) Opioid Use Disorder Recruiting 2025-10-14
NCT06391125 LIMIT Trial - Lidocaine With Intramuscular Injection of Benzathine Penicillin G for… Syphilis Infection Recruiting 2025-03-25
NCT06384573 DIAN-TU Amyloid Removal Trial (ART) in Dominantly Inherited Alzheimer's Disease Alzheimer's Disease Active, Not Recruiting 2026-07-27
NCT02181257 Extracorporeal Photopheresis for Medicare Recipients of Lung Allografts Bronchiolitis Obliterans Syndrome (BOS) Active, Not Recruiting 2026-04-06
Phase 2/3
NCT05552157 A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a… Alzheimers Disease Recruiting 2026-07-27
NCT06647498 A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a… Alzheimers Disease Recruiting 2026-07-27
NCT01760005 Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study… Alzheimers Disease Active, Not Recruiting 2026-07-27
NCT05269394 Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study… Alzheimers Disease Active, Not Recruiting 2026-07-27
Phase 2
NCT06687772 CNS-Relapse Prevention in High-Risk Diffuse Large B-cell Lymphoma With Thiotepa-based… Diffuse Large B Cell Lymphoma Recruiting 2026-08-28
NCT04318717 Pembrolizumab and Hypofractionated Radiation Therapy for the Treatment of Mucosal Melanoma Mucosal Melanoma of the Head and Neck Recruiting 2026-08-27
NCT06867549 Slow Wave Induction by Propofol to Eliminate Depression (SWIPED) Stage II Depression Recruiting 2026-08-27
NCT07174687 SGLT2 Inhibitors in Geographic Atrophy Retinal Degeneration Recruiting 2026-08-26
NCT07689162 Liposomal Bupivacaine vs Standard Bupivacaine for Post-Rhinoplasty Analgesia Pain, Postoperative Recruiting 2026-08-18
NCT06240754 Enasidenib for Patients With Clonal Cytopenia of Undetermined Significance and Mutations… Clonal Cytopenia of Undetermined Significance Recruiting 2026-08-10
NCT06483100 Measurable Residual Disease-Guided Post-Transplant Elranatamab Maintenance Multiple Myeloma Recruiting 2026-08-06
NCT02476786 Endocrine Treatment Alone for Elderly Patients With Estrogen Receptor Positive Operable… Breast Cancer Recruiting 2026-07-27
NCT06702033 The Minimalist Trial-2 HPV-Related Oropharynx Squamous Cell Carcinoma Recruiting 2026-07-24
NCT07392970 Motixafortide for MRD Sensitization in AML Acute Myeloid Leukemia Recruiting 2026-07-24

Disease areas by active trials, top 10 of 56

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