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An AI-Generated, Personalized Question Prompt List Intervention for Patients With Hematologic Cancers

StatusRecruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 4 months later Aug 31, 2026 → Dec 31, 2026
See other at-risk trials from Washington University School of Medicine

Record History

  1. Primary and study completion pushed from Aug 31, 2026 to Dec 31, 2026 Eligibility criteria expanded, about 12 words · Secondary endpoints: details revised at 4 of 4 entries Show 2 more changesShow less
    • Eligibility criteria expanded, about 12 words
    • Secondary endpoints: details revised at 4 of 4 entries
  2. Primary and study completion pushed from Apr 30, 2026 to Aug 31, 2026 Eligibility criteria expanded, about 30 wordsv4 Show 1 more changeShow less
    • Eligibility criteria expanded, about 30 words

    See this version in full on ClinicalTrials.gov ↗

  3. Eligibility criteria expanded, about 36 wordsv3 See this version in full on ClinicalTrials.gov ↗
  4. Trial status: Not Yet Recruiting to Recruiting Start date changed from estimate of Nov 28, 2025 to Dec 26, 2025 · Site details revisedv2 Show 2 more changesShow less
    • Start date changed from estimate of Nov 28, 2025 to Dec 26, 2025
    • Site details revised
  5. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The goal of this study is to evaluate the feasibility and preliminary efficacy of an artificial intelligence (AI)-generated personalized question prompt list (a list of suggested questions to ask during outpatient appointments) for patients with hematologic cancers. The intervention will involve tailoring a standardized prompt to patients' individual characteristics and concerns. This prompt will then be used to ask Washington University's (WashU) HIPAA compliant ChatGPT to generate personalized question lists for outpatient appointments. Analyses will assess the impact of personalized QPLs on patients' question-asking behavior; communicative self-efficacy; and self-reported amount and satisfaction with information obtained about their disease and its treatment. Sub-analyses will explore patterns in questions generated by WashU ChatGPT. Patients will also provide feedback pertaining to the perceived helpfulness and ease-of-use of WashU-ChatGPT-generated question lists, as well as their attitudes and intentions regarding use of AI chatbots and whether they would engage in pre-appointment AI-assisted question brainstorming independently in the future.
Trial Details
NCT Number NCT07226934
Lead Sponsor Washington University School of Medicine
Conditions Lymphoma, Multiple Myeloma
Enrollment 40 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov