Sponsor Pipeline

National Institute of Mental Health (NIMH) Clinical Trial Pipeline

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
42
Active Trials
37
Recruiting
10
Disease Areas
What Changed in the Last 30 Days
First PostedNew Trial FilingPhaseStatus
2026-06-11 NCT07640802 Psychotherapy for Irritability in Youth: Comparing Active Treatment to Nonactive… Not Yet Recruiting
2026-06-04 NCT07625345 Evaluation of [11C]ZTP-1 to Image PDE4B Phase 1 Recruiting
Active Trials by Phase
Phase 2
4
Phase 1
11
Early Phase 1
1
Not specified
26
Active Trials — top 25 of 42
NCT IDTitleConditionStatus
Phase 2
NCT06511908 Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic… Suicide Recruiting
NCT00018057 Study of Neuro-Cognitive Correlates of Pediatric Anxiety Disorders Anxiety Disorders Recruiting
NCT06595953 Gaze-Contingent Music Therapy Augmentation of CBT for Pediatric Anxiety Psychiatric Disorders Recruiting
NCT02543983 Neurobiology of Suicide Healthy Volunteers Recruiting
Phase 1
NCT03973268 Mechanism of Action Underlying Ketamine's Antidepressant Effects: The AMPA Throughput… Depression Recruiting
NCT06920628 PET Imaging of Cyclooxygenase-1 in Participants With Neurological Manifestations of… Long COVID Recruiting
NCT04582916 PET Imaging of Cyclooxygenase in Participants With Major Depressive Disorder (MDD) Depression Recruiting
NCT04396873 PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease Parkinson's Disease Recruiting
NCT05703685 [18F]PF-06445974 to Image PDE4B in Major Depressive Disorder Using PET Depression Recruiting
NCT06795581 PET Imaging of Phosphodiesterase-4B (PDE4B) in Alcohol Use Disorder Alcohol Use Disorder Recruiting
NCT06874205 Assessment of 11C-JMJ-129 for Imaging PDE4D in Brain and Whole Body of Healthy Volunteers Healthy Recruiting
NCT07027839 Acute Effects of Alcohol on PET Imaging of Phosphodiesterase-4B (PDE4B) Alcohol Use Disorder Recruiting
NCT03065335 Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and… Healthy Volunteer Recruiting
NCT07169630 PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or… Alzheimer s Disease Recruiting
NCT07625345 Evaluation of [11C]ZTP-1 to Image PDE4B Healthy Recruiting
Early Phase 1
NCT06484088 Study Brain Mechanisms of Frustration With Magnetoencephalography in Healthy Volunteers Irritability Recruiting
Not specified
NCT05666726 State-dependent Interoception, Value-based Decision-making, and Introspection Stress Recruiting
NCT04798274 Role of GABAergic Transmission in Auditory Processing in Autism Spectrum Disorder Autism Spectrum Disorder Recruiting
NCT04631042 Developing Brain, Impulsivity and Compulsivity Typical Development Recruiting
NCT03388606 Characterization and Treatment of Adolescent Depression Depression Recruiting
NCT06462196 Natural History of Depression, Bipolar Disorder and Suicide Risk Behavioral Symptoms Recruiting
NCT05669703 NIMH Rhythms and Blues Study: A Prospective Natural History Study of Motor Activity, Mood… Bipolar Disorder Recruiting
NCT01617408 Brain Stimulation and Vision Testing fMRI Recruiting
NCT01434368 A Longitudinal Investigation of the Endocrine and Neurobiologic Events Accompanying… fMRI Recruiting
NCT00001360 Studies of Blood Flow to the Brain During Thought Healthy Volunteer Recruiting
View all 42 active National Institute of Mental Health (NIMH) trials with filters →
Disease Areas
Get alerts when National Institute of Mental Health (NIMH)'s trials change
Status changes, date slips, and new filings — detected daily, delivered to your inbox.
Start monitoring free