Disease Landscape

Dementia Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-08-16
666
Active Trials
373
Recruiting
28
Phase 3
410
Sponsors
78
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-08-15 NCT06112860
OTC Hearing Aid and MCI · Northwestern University
date change Completion pushed: 2026-12-31 -> 2027-03-30
2026-08-15 NCT07742189
Medication Collaboration Feasibility Study · Northwestern University
Recruitment opened
2026-08-15 NCT05617014
Alzheimer's Disease Neuroimaging Initiative 4 · University of Southern California
Trial sites expanded: 62 -> 65 locations
2026-08-14 NCT07213700
InRAD Observational Study · Stichting International Registry for Alzheimer's Disease and other Dementias Foundation
Trial sites expanded: 7 -> 11 locations
2026-08-14 NCT06064890
A Study to Evaluate the Safety and Effect of AVB-101, a Gene Therapy Product, in Subjects… · AviadoBio Ltd
date change Primary completion pushed: 2026-04-01 -> 2027-04-01
2026-08-13 NCT07370311
A Culturally Adapted Decision Aid Intervention to Support Chinese American Dementia… · Yaolin Pei
date change Primary completion moved earlier: 2027-07-31 -> 2027-06-30
2026-08-13 NCT06819852
Acute Hospital Care at Home for People Living With Dementia · Brigham and Women's Hospital
date change Primary completion pushed: 2028-05 -> 2029-04-01
2026-08-13 NCT06819852
Acute Hospital Care at Home for People Living With Dementia · Brigham and Women's Hospital
date change Completion pushed: 2028-05 -> 2029-04-01
2026-08-11 NCT06209515
Sociodemographic Factors and Criminal Behaviour Preceding Neurodegenerative Disease… · Kuopio University Hospital
date change Primary completion pushed: 2027-12-31 -> 2029-12-31
2026-08-11 NCT06209515
Sociodemographic Factors and Criminal Behaviour Preceding Neurodegenerative Disease… · Kuopio University Hospital
date change Completion pushed: 2027-12-31 -> 2029-12-31
2026-08-11 NCT07279103
Multisensory Environment-Based Occupational Therapy for Alzheimer's Patients · Hacettepe University
overall status: Enrolling by Invitation → Completed
2026-08-11 NCT07279103
Multisensory Environment-Based Occupational Therapy for Alzheimer's Patients · Hacettepe University
date change Primary completion pushed: 2025-06-01 -> 2025-07-10
2026-08-11 NCT07688213
A Study to Investigate the Safety and Effectiveness of SAR448851 in Participants With… · Sanofi
Recruitment opened
2026-08-11 NCT07210528
Safety Of Nrtis for Alzheimer's Therapeutic Advancement in Singapore Study · National University Hospital, Singapore
Enrollment closed, study ongoing
2026-08-11 NCT07210528
Safety Of Nrtis for Alzheimer's Therapeutic Advancement in Singapore Study · National University Hospital, Singapore
date change Primary completion pushed: 2026-03 -> 2026-09
2026-08-11 NCT07210528
Safety Of Nrtis for Alzheimer's Therapeutic Advancement in Singapore Study · National University Hospital, Singapore
date change Completion pushed: 2026-04 -> 2026-09
2026-08-11 NCT06467461
5-HT RBD REM Sleep Behavior Disorder · University of Minnesota
Enrollment closed, study ongoing
2026-08-11 NCT06467461
5-HT RBD REM Sleep Behavior Disorder · University of Minnesota
Enrollment increased: 60 -> 66 participants
2026-08-09 NCT07505095
Efficacy of Lecanemab at Different Therapeutic Doses for Alzheimer's Disease (AD) in… · Second Affiliated Hospital, School of Medicine, Zhejiang University
Sponsor changed: Second Affiliated Hospital, School of Medicine, Zhejiang University -> Second Affiliated Hospital, Zhejiang University, School of Medicine
2026-08-09 NCT07152418
Therapeutic Efficacy of Monoclonal Antibody Drugs for Alzheimer's Disease Based on PET… · Second Affiliated Hospital, School of Medicine, Zhejiang University
Sponsor changed: Second Affiliated Hospital, School of Medicine, Zhejiang University -> Second Affiliated Hospital, Zhejiang University, School of Medicine
Showing 20 of 78 changes detected in the last 30 days.
New Sponsor Entrants, Last 90 Days
First PostedTrialSponsorPhase
2026-08-13 NCT07763392 Establishing Normal Cognitive Test Scores for Adults Using a Voice-Enabled Digital… The Neurology Center of Southern California NEW
2026-08-11 NCT07757204 An Open-label Long-term Safety Study of Buntanetap in Participants With AD Annovis Bio Inc. NEW Phase 2/3
2026-08-11 NCT07758660 Alzheimer's Disease Research Center (ADRC) PET Component Study Patrick Lao NEW Phase 2
2026-08-10 NCT07755631 The BASIC-S Feasibility Study for Vascular Risk Reduction Andrew Appleton NEW
2026-08-05 NCT07747610 Effects of Lifestyle and Cognitive Play-Based Nursing Intervention on Dementia Risk Al-Zaytoonah University of Jordan NEW
2026-07-23 NCT07721701 Digital Dementia Registry Bavaria (digiDEM Bayern): a Multicentre, Prospective… University of Erlangen-Nürnberg Medical School NEW
2026-07-22 NCT07718906 Neuromodulation for Behavioral Changes in Neurological Disorders West Virginia University NEW
2026-07-14 NCT07700615 Mexidol® Efficacy and Safety in Treatment of VCIND in Older Adults Pharmasoft NEW Phase 4
2026-07-14 NCT07701161 Development of a Home Test for Measuring Blood P-tau217 in Alzheimer's Disease Using the… Neurogen Biomarking LLC NEW
2026-07-10 NCT07695194 Conectando Corazones Intervention in Family Caregivers of an Older Adult With Dementia Universidad de la Sabana NEW
Active Trials by Phase
Phase 4
11
Phase 3
18
Phase 2/3
10
Phase 2
36
Phase 1/2
18
Phase 1
13
Early Phase 1
6
Not specified
554
Active Trials — top 25 of 666
NCT IDTitleSponsorStatus
Phase 4
NCT06093126 Lemborexant for Insomnia in a Patient With Dementia: An N-of-1 Trial Nova Scotia Health Authority Recruiting
NCT05590637 Comparing Antipsychotic Medications in LBD Over Time The University of Texas Health Science Center at San Antonio Recruiting
NCT07284290 Elucidating the Role of Cholinergic Degeneration in Cognitive Fluctuations in Lewy Body… Virginia Commonwealth University Recruiting
NCT07485283 Recombinant Herpes Zoster Vaccine for Prevention of Cardiovascular Events and Dementia Tor Biering-Sørensen Recruiting
NCT07604896 Evaluating the Efficacy and Safety of Lecanemab in Alzheimer's Disease Through… First Affiliated Hospital of Wenzhou Medical University Recruiting
NCT04262206 Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults Duke University Recruiting
NCT06662526 Lithium for Prevention of Cognitive Declining in Mood Illnesses University of Chile Not Yet Recruiting
NCT05586750 Statins in Reducing Events in the Elderly Mind (STAREE-Mind) Imaging Substudy Monash University Active, Not Recruiting
NCT01453127 DaTSCAN Imaging in Aging and Neurodegenerative Disease Mayo Clinic Enrolling by Invitation
NCT00950430 Imaging of Brain Amyloid Plaques in the Aging Population Mayo Clinic Enrolling by Invitation
NCT05514106 MIBG in Aging and Neurologic Disorders Mayo Clinic Enrolling by Invitation
Phase 3
NCT03848312 Preventing Alzheimer's With Cognitive Training University of South Florida Recruiting
NCT07251023 Efficacy and Safety of DMB-I (INN: Latrepirdine) in Patients With Alzheimer Type Dementia Bigespas LTD Recruiting
NCT06534723 Phase 3 Clinical Trial of Wujia Yizhi Granules in the Treatment of Mild-to-moderate… Sichuan Jishengtang Pharmaceutical Co., Ltd. Recruiting
NCT05397639 Masupirdine for the Treatment of Agitation in Dementia of the Alzheimer's Type Suven Life Sciences Limited Recruiting
NCT07234695 LEvetiracetam to Prevent Seizures in Symptomatic Alzheimer's Disease in Adults With Down… Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau Recruiting
NCT07422857 Evaluate the Use of [18F]-APN-1607 PET in Subjects With AD-related Cognitive Impairment… JYAMS PET Research & Development Limited Recruiting
NCT07083154 GLP-1/GCG Dual Agonist in Type 2 Diabetes With Early Dementia (LIGHT-COG Study) The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School Recruiting
NCT07602582 A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM… Eli Lilly and Company Recruiting
NCT07724132 An Evaluation of Treatments for Sustained Clinical Response (18 Months) in Symptomatic… University College, London Recruiting
NCT03108846 Escitalopram for Agitation in Alzheimer's Disease JHSPH Center for Clinical Trials Active, Not Recruiting
NCT05470816 Tranexamic Acid to Reduce Delirium After Gastrointestinal Surgery: the TRIGS-D Trial Bayside Health Active, Not Recruiting
NCT03804229 Efficacy and Safety of Butylphthalide Soft Capsule for the Treatment of Vascular Dementia Capital Medical University Active, Not Recruiting
NCT07191028 Alzheimer's Disease THErapy With NEuroaid II Moleac Pte Ltd. Not Yet Recruiting
NCT05738486 A Study of Different Donanemab (LY3002813) Dosing Regimens in Adults With Early… Eli Lilly and Company Active, Not Recruiting
See all 666 active Dementia trials with filters →
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