Sponsor pipeline

Duke University clinical trial pipeline

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319 active trials 190 recruiting 56 disease areas 62 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-10-02

What changed in the last 30 days showing 41 of 62 changes on 20 trials

2026-09-04
Withdrawn before enrolling
Trial withdrawn: Funding not obtained
NCT06327373 A Feasibility Study of Supplemental Oxygen to Improve Pulmonary Hypertension in People… · Phase 1/2
2026-09-12
Reclassified as terminated (was completed)
Trial terminated: Study was terminated at the completion of Aim 1 due to lack of time and funding to complete the more complex Aim 2.
Results posted: 2026-09-11
NCT05764564 External Body Pressure in Heart Failure With Preserved Ejection Fraction
2026-09-09
Trial status changed: Active, Not Recruiting → Suspended
Recruitment suspended: Study is suspended due to lack of funds. Will resume as soon as funding is secured.
Primary completion pushed: 2026-05 → 2027-12
Completion pushed: 2026-05 → 2027-12
NCT04544735 Improving Women's Function After Pelvic Radiation
2026-10-02
Primary completion pushed: 2026-09-30 → 2026-12-30
Completion pushed: 2026-09-30 → 2026-12-30
NCT05459077 Addressing Barriers to Anti-hypertensive Medication Adherence Among PLWH Who Have…
2026-09-22
Primary completion pushed: 2026-11 → 2027-09
Completion pushed: 2026-11 → 2027-09
NCT06041789 Effect of Acetylcholinesterase Inhibitors on Bone Metabolism · Phase 2
2026-09-23
Primary completion pushed: 2026-06-30 → 2027-06-30
Completion pushed: 2026-06-30 → 2027-06-30
NCT04874220 Neural Correlates of Real World Spatial Navigation in Humans
2026-09-04
Primary completion pushed: 2026-06-30 → 2027-06-30
Completion pushed: 2026-06-30 → 2027-06-30
NCT06759558 Allopregnanolone (Zuranolone) in Post-stroke Depression · Phase 2
2026-09-09
Primary completion pushed: 2026-07-01 → 2027-10-01
Completion pushed: 2026-08-01 → 2027-10-01
NCT07589764 Pilot Trial Utilizing β-hydroxy-β-methylbutyrate to Lower IGFBP7 Levels in People With ALS · Phase 1
2026-09-10
Primary completion pushed: 2026-12-31 → 2027-06-15
Completion pushed: 2026-12-31 → 2027-07-01
NCT04956978 Shared Decision Making to Address Racial Disparities in Oral Anticoagulation in NVAF
2026-09-09
Primary completion pushed: 2029-11 → 2030-04
Completion pushed: 2030-08 → 2031-01
NCT07647679 Lattice Radiotherapy for Adults With Large Tumors
2026-09-09
Primary completion pushed: 2028-08 → 2029-01-01
Recruitment opened
Completion pushed: 2028-10 → 2029-07-01
NCT07390773 Building Relationship, Improving Dialogue, and Growing Empathy (BRIDGE): An Intervention…
2026-09-04
Primary completion pushed: 2028-08 → 2029-09
Completion pushed: 2028-08 → 2029-09
NCT07685249 Rehabilitation and Sex Therapy to Optimize Recovery After Prostate Cancer Treatment
2026-09-04
Primary completion pushed: 2026-08-31 → 2029-07-31
Completion pushed: 2026-08-31 → 2029-07-31
NCT06703541 ADRC Clinical Cohort (Alzheimer's Disease)
2026-09-04
Primary completion pushed: 2027-01 → 2028-01
Completion pushed: 2027-01 → 2028-01
NCT03190837 A Long-term Follow-up Study of Gaucher Disease
2026-10-02
Primary endpoint(s) modified
NCT07811258 Improving Adherence to Chronic Disease Medication Regimens Among Patients With Recently…
2026-10-02
Enrollment reduced: 128 → 4 participants
Completion pushed: 2027-03-31 → 2027-06-30
NCT06229418 Developing and Testing Drone-Delivered AEDs for Cardiac Arrests In Rural America
2026-10-02
Enrollment reduced: 420 → 212 participants
NCT06906640 Implementation pRogram to Improve Screening and Management for CKD in Diabetes (IRIS-CKD)…
2026-10-02
Enrollment reduced: 750 → 500 participants
NCT06906627 Implementation pRogram to Improve Screening and Management for CKD in Diabetes (Program…
2026-09-30
Recruitment opened
NCT07603375 Upfront Chemotherapy With Radiation Therapy (CRT) Followed by Chemotherapy in Localized… · Phase 2
2026-09-30
Trial completed
Final enrollment: 137 participants (planned 80)
Primary completion confirmed: February 2026 (last estimated December 2026)
NCT06177977 SS-HH-OCT as a Novel Diagnostic Modality for Early-Onset Retinal Dystrophies (EORDs)

New trial filings, last 30 days

First postedTrialPhaseStatus
2026-09-25 NCT07843043 Feasibility of a Dyadic Music-based Intervention for Persons Living With Dementia and… Not Yet Recruiting
2026-09-23 NCT07836010 Suzetrigine Added to Multimodal Analgesia for Women Undergoing Minimally Invasive… Phase 4 Not Yet Recruiting
2026-09-17 NCT07824115 The Hear Clear Study Not Yet Recruiting
2026-09-17 NCT07825688 TxAccess and Dd-cfDNA for Improved Care of Patients With Delayed Graft Function Not Yet Recruiting
2026-09-11 NCT07815782 Tailored mHealth Coaching and Social Resource Support in Kidney Transplantation Not Yet Recruiting
2026-09-10 NCT07811258 Improving Adherence to Chronic Disease Medication Regimens Among Patients With Recently… Not Yet Recruiting
2026-09-09 NCT07810322 Pilot Testing of the emPath Platform to Improve Medication for Opioid Use Disorder (MOUD)… Recruiting
2026-09-08 NCT07807774 FlexED: National Substudy Recruiting
2026-09-04 NCT07805382 Dynamic Relationships Between Estrogen Fluctuations, Sleep, and Psychiatric Complexity… Not Yet Recruiting
2026-09-03 NCT07803536 Effect of Late Ripcord Removal From Glaucoma Drainage Device Not Yet Recruiting

Active trials by phase

Early Phase 1
3
Phase 1
7
Phase 1/2
6
Phase 2
18
Phase 3
4
Phase 4
25
Not charted: 256 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 319

NCT IDTitleConditionStatusUpdated
Phase 4
NCT06909565 Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb… Percutaneous Coronary Intervention Recruiting 2026-09-28
NCT07191873 Tirzepatide in Idiopathic Intracranial Hypertension Trial Idiopathic Intracranial Hypertension (IIH) Recruiting 2026-09-15
NCT04262206 Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults Cognitive Impairment, Mild Recruiting 2026-09-01
NCT07218211 Enhancing PrEP Uptake and Retention Among Latine TGW and GBM in the South Using… HIV Prevention Recruiting 2026-08-26
NCT07089901 Project DEDUCE: Digital Envirotyping to Develop Understanding of Cigarette Smoking and… Smoking Recruiting 2026-07-23
NCT07348614 Flex Appeal: Evaluating the Efficacy of Anesthetic Techniques for Manipulation of Knees… Knee Stiffness After Total Knee Arthroplasty Recruiting 2026-06-03
NCT06962306 Optimizing Perioperative Analgesia to Lower Pain Following Cleft Palate Surgery Cleft Palate Recruiting 2026-04-14
NCT04454203 Femoral Peri-arterial Local Anesthetic Injection Via Peri-arterial Perineural Catheter… Tourniquet Hypertension Recruiting 2026-03-23
NCT07158814 Safety of RSV Preventive Monoclonal Antibody Fever Recruiting 2026-03-16
NCT06576830 Optimization of Pediatric Tonsillectomy to IMprove AnaLgesia Pain, Postoperative Recruiting 2025-12-05
NCT07836010 Suzetrigine Added to Multimodal Analgesia for Women Undergoing Minimally Invasive… Postoperative Pain Not Yet Recruiting 2026-09-23
NCT07228039 ESP Blocks for Posterior Spinal Fusion Postoperative Pain Not Yet Recruiting 2026-08-27
NCT07444827 Targeted Nerve Injection to the Knee (Nerve to Vastus Medialis): Comparing Two Adductor… Anesthesia, Local Not Yet Recruiting 2026-08-27
NCT06854029 NOTRE: Optimizing Long-Acting Pre-Exposure Prophylaxis and Medications for Opioid Use… HIV Infections Not Yet Recruiting 2026-08-26
NCT06249165 VictORION-INCLUSION: Evaluating Inclisiran for Cholesterol Managment in Heart Disease Atherosclerotic Cardiovascular Disease Active, Not Recruiting 2026-07-29
NCT07566312 Study of QL Analgesic Response and Extent Acute Pain Not Yet Recruiting 2026-07-08
NCT07686692 IV Iron Therapy for Older Adults With Heart Failure With Preserved Ejection Fraction and… Heart Failure With Preserved Ejection Fraction Not Yet Recruiting 2026-07-07
NCT07429292 SPARK Study - Sympathetic Periarterial Radial Block in Healthy Volunteers Healthy Volunteers Not Yet Recruiting 2026-06-17
NCT07614802 Exparel and Dexamethasone Postoperative Pain Not Yet Recruiting 2026-06-03
NCT07390578 Upneeq vs. Lumify Ptosis Acquired Ptosis Not Yet Recruiting 2026-05-22
NCT05757167 Improving Neonatal Health Through Rapid Malaria Testing in Early Pregnancy With… Malaria,Falciparum Active, Not Recruiting 2026-05-07
NCT07560046 Combating Related Epidemics in HCV HIV - Human Immunodeficiency Virus Not Yet Recruiting 2026-05-05
NCT05127109 The PASTDUe Nutrition Ecosystem Project (PASTDUe) Diet, Healthy Active, Not Recruiting 2026-04-23
NCT03144206 Hyperbaric Oxygen Therapy for Soft Tissue Sarcoma Pilot Study Sarcoma Active, Not Recruiting 2026-03-27
NCT05634720 Hepatic Artery Chemotherapy for Patients With Localized Pancreas Cancer Pancreatic Ductal Adenocarcinoma Active, Not Recruiting 2026-01-26
See all 319 active Duke University trials with filters →

Disease areas by active trials, top 10 of 56

Breast Cancer (13) · Hypertension (11) · Heart Disease (10) · Epilepsy (9) · Heart Failure (9) · Dementia (8) · Depression (7) · Diabetes (7) · Obesity (7) · Chronic Kidney Disease (6)

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