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Dynamic Relationships Between Estrogen Fluctuations, Sleep, and Psychiatric Complexity Among Adolescent Females With ADHD

Name: Dynamic Relationships Between Estrogen Fluctuations, Sleep, and Psychiatric Complexity Among Adolescent Females With ADHD — clinical trial record (NCT07805382)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

Study acronym: DREAMS

StatusNot Yet Recruiting

PhaseNot specified

SponsorDuke University

Started2026-09

View on ClinicalTrials.gov ↗

Duke University

455 trials monitored

See 53 trials at risk

ADHD

385 trials monitored

See 19 trials at risk

The purpose of the study is to establish the feasibility of collecting estradiol (E2), Garmin-measured sleep, and ecological momentary assessments (EMA) of ADHD and related symptoms (mood, anxiety, executive functioning) across menstrual cycles among 20 peripubertal female adolescents aged 11-15 with ADHD, and to explore links between within-individual E2 variability, sleep, and EMA-derived outcomes.

Trial Details

NCT Number	NCT07805382
Lead Sponsor	Duke University
Conditions	ADHD
Enrollment	30 participants
Start Date	2026-09
Primary Completion	2027-08 (estimated)
Study Completion	2027-08 (estimated)
Updated on ClinicalTrials.gov	2026-09-21