Sponsor Pipeline

National Institute of Mental Health (NIMH) Clinical Trial Pipeline

Data updated daily from ClinicalTrials.gov — last refresh 2026-08-16
47
Active Trials
41
Recruiting
10
Disease Areas
4
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-08-14 NCT05669703
NIMH Rhythms and Blues Study: A Prospective Natural History Study of Motor Activity, Mood…
date change Primary completion pushed: 2026-07-31 -> 2027-07-31
2026-08-14 NCT05669703
NIMH Rhythms and Blues Study: A Prospective Natural History Study of Motor Activity, Mood…
date change Completion pushed: 2026-07-31 -> 2027-07-31
2026-08-13 NCT05172271
Transcranial Electric Stimulation Therapy (TEST) for Treatment Resistant Depression (TRD)
date change Primary completion moved earlier: 2027-07-31 -> 2025-12-04
2026-07-30 NCT07640802
Psychotherapy for Irritability in Youth: Comparing Active Treatment to Nonactive…
Enrollment increased: 300 -> 410 participants
New Trial Filings, Last 30 Days
First PostedTrialPhaseStatus
2026-08-14 NCT07764536 Augmenting Parent Management Training for Child Temper Outbursts Using a Digital Tool Not Yet Recruiting
Active Trials by Phase
Phase 2
4
Phase 1/2
1
Phase 1
12
Early Phase 1
1
Not specified
29
Active Trials — top 25 of 47
NCT IDTitleConditionStatus
Phase 2
NCT06511908 Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic… Suicide Recruiting
NCT02543983 Neurobiology of Suicide Healthy Volunteers Recruiting
NCT00018057 Study of Neuro-Cognitive Correlates of Pediatric Anxiety Disorders Anxiety Disorders Recruiting
NCT06595953 Gaze-Contingent Music Therapy Augmentation of CBT for Pediatric Anxiety Psychiatric Disorders Recruiting
Phase 1/2
NCT05608434 Development of Virtual Reality-based Interventions to Strengthen Cognitive Skillsets… Attention Deficit Hyperactivity Disorder Recruiting
Phase 1
NCT03973268 Mechanism of Action Underlying Ketamine's Antidepressant Effects: The AMPA Throughput… Depression Recruiting
NCT04396873 PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease Parkinson's Disease Recruiting
NCT04582916 PET Imaging of Cyclooxygenase in Participants With Major Depressive Disorder (MDD) Depression Recruiting
NCT05703685 [18F]PF-06445974 to Image PDE4B in Major Depressive Disorder Using PET Depression Recruiting
NCT06795581 PET Imaging of Phosphodiesterase-4B (PDE4B) in Alcohol Use Disorder Alcohol Use Disorder Recruiting
NCT06874205 Assessment of 11C-JMJ-129 for Imaging PDE4D in Brain and Whole Body of Healthy Volunteers Healthy Recruiting
NCT06920628 PET Imaging of Cyclooxygenase-1 in Participants With Neurological Manifestations of… Long COVID Recruiting
NCT07027839 Acute Effects of Alcohol on PET Imaging of Phosphodiesterase-4B (PDE4B) Alcohol Use Disorder Recruiting
NCT07625345 Evaluation of [11C]ZTP-1 to Image PDE4B Healthy Recruiting
NCT03065335 Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and… Healthy Volunteer Recruiting
NCT07169630 PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or… Alzheimer s Disease Recruiting
NCT07686393 PET Imaging of Noradrenergic Transmission in the Brain Healthy Recruiting
Early Phase 1
NCT06484088 Study Brain Mechanisms of Frustration With Magnetoencephalography in Healthy Volunteers Irritability Recruiting
Not specified
NCT04877977 Long-term Observation of Participants With Mood Disorders Depression Recruiting
NCT04950309 Characterization of an Optically Pumped Magnetometer (OPM) Magnetoencephalography (MEG)… Normal Physiology Recruiting
NCT04798274 Role of GABAergic Transmission in Auditory Processing in Autism Spectrum Disorder Autism Spectrum Disorder Recruiting
NCT04639830 Electrophysiologic Sleep Phenotyping and Sleep-Dependent Neuro-maturation in Clinical and… Healthy Children Recruiting
NCT00271622 The Neurodevelopmental and Behavioral Phenotyping Screening Protocol Neurologic Disorders Recruiting
NCT05666726 State-dependent Interoception, Value-based Decision-making, and Introspection Stress Recruiting
NCT01266577 Development of Magnetic Resonance Spectroscopic Imaging Techniques for Imaging… Brain Mapping Recruiting
See all 47 active National Institute of Mental Health (NIMH) trials with filters →
Disease Areas
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