Disease landscape

Anxiety clinical trials

Get alerts when Anxiety trials change

1,528 active trials 761 recruiting 26 Phase 3 893 sponsors 260 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-08-28

What changed in the last 30 days showing 60 of 260 changes on 20 trials

2026-07-30
Withdrawn before enrolling
Trial withdrawn: This study does not meet the clinical trial definition under FDAAA 801 / NIH policy - participants aren't prospectively...
Enrollment reduced: 20 → 0 participants
NCT07714889 Development of an Accessible Cognitive Behavioral Therapy Digital Therapeutic for… · Toivoa Inc
2026-08-14
Trial terminated
Trial terminated: For logistical reasons at one study site.
Enrollment reduced: 60 → 41 participants
Primary completion pushed: 2024-12 → 2025-03-30
NCT06118606 Pilot Study of a Multidisciplinary Intervention in ICU Survivors at Risk for… · Region Stockholm
2026-08-19
Withdrawn before enrolling
Trial withdrawn: The collaborator has no intention to initiate the study at this moment.
Enrollment reduced: 200 → 0 participants
NCT06924814 Technology-Based Distractions for Minor Procedures · Stanford University
2026-08-14
Trial status changed: Recruiting → Withdrawn
Trial withdrawn: operational constraints beyond control of the study staff has forced the closure of the study.
Enrollment reduced: 40 → 0 participants
NCT07694934 Operation Calm: VR Nature-Based Mindfulness to Reduce Pediatric Surgical Anxiety · McGill University
2026-08-12
Trial terminated
Trial terminated: The study was terminated due to limited resources and the loss of key study personnel, which made completion of the pla...
Enrollment reduced: 60 → 14 participants
Primary completion moved earlier: 2028-04 → 2023-12-31
Completion moved earlier: 2028-12 → 2023-12-31
NCT05388110 SKY Breath Intervention · University of California, San Francisco
2026-08-11
Recruitment suspended
Recruitment suspended: Funding for this study was discontinued by the sponsor after the first year.
Primary completion pushed: 2026-12 → 2028-12-31
Completion pushed: 2026-12 → 2028-12-31
NCT05541887 Use Muscadine Wine Nutraceuticals to Improve Brain Health, Cognition, and Mental Health · University of Florida
2026-08-27
Primary completion pushed: 2025-10 → 2026-01-31
Completed without a posted recruiting period
Completion pushed: 2025-10 → 2026-01-31
NCT07081061 Clinical Outcomes of a Digital Mental Health Intervention for Moderate/Severe Depression… · Teladoc Health
2026-08-19
Primary completion pushed: 2027-06 → 2027-10-14
Trial sites reduced: 60 → 51 locations
Completion pushed: 2027-06 → 2027-10-14
NCT06701903 Study of ITI-1284 as Monotherapy Treatment in Patients With Generalized Anxiety Disorder · Intra-Cellular Therapies, Inc. · Phase 2
2026-08-21
Primary completion pushed: 2026-05-01 → 2026-08-30
Completion pushed: 2026-05-01 → 2026-08-30
NCT06708715 Stress Reduction After Use of a Haptic Vibrotactile Trigger Technology Patch: Analysis… · SuperPatch Limited LLC
2026-08-28
Primary completion pushed: 2026-08-31 → 2027-11-01
Completion pushed: 2026-08-31 → 2027-11-01
NCT07228299 Supporting Families in the ICU · Indiana University
2026-08-28
Primary completion pushed: 2025-06-30 → 2025-12-06
Trial completed
Enrollment increased: 220 → 260 participants
Completion pushed: 2025-06-30 → 2026-04-14
NCT04426461 Approach-Avoidance, Computational Framework for Predicting Behavioral Therapy Outcome… · Laureate Institute for Brain Research, Inc.
2026-08-27
Primary completion pushed: 2026-02-19 → 2027-03
Enrollment closed, study ongoing
Completion pushed: 2026-08 → 2027-03
NCT05559749 Collaborative Care for Anxiety and Depression in Epilepsy · Wake Forest University Health Sciences
2026-08-26
Primary completion pushed: 2025-09-30 → 2026-05-05
Enrollment reduced: 355 → 210 participants
Completed without a posted recruiting period
Trial sites expanded: 0 → 4 locations
Completion pushed: 2025-09-30 → 2026-05-05
NCT06600139 Screening to Identify Parents in Need of Mental Health Support: A Feasibility Study in… · Karolinska Institutet
2026-08-26
Primary completion pushed: 2026-04-30 → 2026-12-30
Completion pushed: 2026-04-30 → 2026-12-30
NCT07384923 The Effect of Vibration Devices on Pain and Discomfort During Local Anesthesia… · King Abdulaziz University
2026-08-26
Primary completion pushed: 2025-09-30 → 2026-05-05
Enrollment reduced: 290 → 155 participants
Completed without a posted recruiting period
Trial sites expanded: 0 → 6 locations
Completion pushed: 2025-09-30 → 2026-05-05
NCT06572865 Identifying Parents in Child Welfare Services Who Need Mental Health Support: Depression… · Karolinska Institutet
2026-08-15
Primary completion pushed: 2025-12 → 2027-12
NCT04014829 Evaluation of Central Sensitization, Fear-Avoidance, and Pain-Pressure Threshold With… · KK Women's and Children's Hospital
2026-08-08
Primary completion pushed: 2026-10 → 2027-12
Recruitment opened
NCT06929208 Heart Rate Variability and Music Listening · KK Women's and Children's Hospital
2026-08-08
Primary completion pushed: 2025-08-31 → 2026-08-31
Completion pushed: 2026-12-31 → 2027-12-31
NCT03226028 Perioperative Music Listening on Anxiety, Analgesia Use and Patient Satisfaction · KK Women's and Children's Hospital
2026-08-08
Primary completion pushed: 2025-12-31 → 2026-12-31
Completion pushed: 2026-12-31 → 2027-12-31
NCT03415620 Perioperative Music Listening on Anxiety, Pain, Analgesia Use and Patient Satisfaction · KK Women's and Children's Hospital
2026-08-08
Primary completion pushed: 2025-12-31 → 2026-12-31
Completion pushed: 2026-12-31 → 2027-12-31
NCT03408717 Evaluation And Risk Assessment For Persistent Postsurgical Pain After Breast Surgery · KK Women's and Children's Hospital

New sponsor entrants, last 90 days sponsors with their first trial in this area

First postedTrialSponsorPhase
2026-08-27 NCT07789808 Activating Voice Journaling for Mental Health With Voice Biomarkers Kintsugi Mindful Wellness, Inc. new
2026-08-27 NCT07790029 Passiflora Incarnata for Dental Extraction Anxiety Ömer faruk Kaygısız new
2026-08-27 NCT07790055 THE EFFECT OF MINDFULNESS IN INFLAMMATION MARKERS (IL-6, TNF-Α, CRP AND CORTISOL) AMONG… Natalia Dewi Wardani, MD new
2026-08-26 NCT07788495 The Effect of Simulation-Based Oxytocin Induction Training on Midwifery Students'… Melisa Gündeş new
2026-08-26 NCT07787000 Antenatal Bre-Lax Education for Perinatal Anxiety Reduction and Self-efficacy Among… Bahria University new
2026-08-25 NCT07785713 Effects of Online Laughter Yoga and Psychoeducation on Perceived Stress and Career… Okan University new
2026-08-24 NCT07782034 40-Hz Audiovisual Stimulation in Schizophrenia Spectrum Disorders National Cheng Kung University new
2026-08-24 NCT07782463 Effect of a Solution-Focused Intervention on Future Anxiety and Life Satisfaction in… Halic University new
2026-08-21 NCT07780331 The Effect of Using Virtual Reality Glasses and Gaming Cards on Fear, Anxiety, and… Bandırma Onyedi Eylül University new
2026-08-20 NCT07776236 Remote Group Cognitive Behavioral Skills Training for Mexican University Students With… Instituto Nacional de Psiquiatría Dr. Ramón de la Fuente new

Active trials by phase

Early Phase 1
9
Phase 1
7
Phase 1/2
4
Phase 2
49
Phase 2/3
6
Phase 3
20
Phase 4
22
Not charted: 1,411 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 1,528

NCT IDTitleSponsorStatusUpdated
Phase 4
NCT07542730 Diphenhydramine as an Adjunct to Moderate Sedation for Procedural First Trimester… University of Rochester Recruiting 2026-08-21
NCT07552246 Comparing Acupuncture With Medication to Reduce Depression, Anxiety and Comorbid Sleep… Duke Kunshan University Recruiting 2026-07-29
NCT07432815 Treatment of Psoriasis With Depression and/or Anxiety With Methotrexate vs Combined… Cairo University Recruiting 2026-05-05
NCT05895383 Self-Adjusted Nitrous Oxide: A Feasibility Study in the Setting of Vasectomy Beth Israel Deaconess Medical Center Recruiting 2026-02-06
NCT07182890 Efficacy of Clostridium Butyricum in Alleviating Anxiety and Depression in Patients With… Xijing Hospital of Digestive Diseases Recruiting 2026-01-05
NCT07187492 Efficacy of Bacillus Coagulans in Alleviating Anxiety and Depression in Patients With… Xijing Hospital of Digestive Diseases Recruiting 2026-01-05
NCT06853431 Determination of ED50 and ED95 With Clinical Efficacy of Intranasal Dexmedetomidine… Second Affiliated Hospital of Wenzhou Medical University Recruiting 2025-12-02
NCT06004115 Processes and Circuitry Underlying Threat Sensitivity as a Treatment Target for Co-morbid… Laureate Institute for Brain Research, Inc. Recruiting 2025-10-31
NCT07192367 Comparison of the Effectiveness Level of Virtual Reality Exposure Therapy With Sertraline… Emine Kanmaz Recruiting 2025-09-25
NCT07113080 Assessing the Efficacy of Lemongrass and Lavender Aromatherapy in Reducing Dental Anxiety… Hiba Ahmed Eltayeb Recruiting 2025-08-08
NCT06843044 Efficacy and Safety of Ranquilon in Patients With Anxiety Disorders Due to Neurasthenia… Valenta Pharm JSC Recruiting 2025-07-08
NCT06218030 Adjunctive Treatment With L-methylfolate for Treatment-Resistant Generalized Anxiety… Queen's University Recruiting 2025-05-25
NCT04221997 Trial With the Treatment of Sertraline in Youth With Generalized, Separation and/or… University of Cincinnati Recruiting 2024-11-01
NCT04245436 Acute and Long-Term Antidepressant Treatment Success in Adolescents With Anxiety (AtLAS-A) University of Cincinnati Recruiting 2024-08-29
NCT04623099 Pharmacogenetically-guided Escitalopram Treatment for Pediatric Anxiety: Aiming to… University of Cincinnati Recruiting 2024-08-29
NCT07753772 Dexmedetomidine-Esketamine Combination on Depression and Anxiety After Laparoscopic… Peking University First Hospital Not Yet Recruiting 2026-08-14
NCT06786429 Managing Hepatitis B (Hep. B) and Human Papilloma Virus (HPV) Related Cancers and Mental… Eunice Dube Not Yet Recruiting 2026-07-30
NCT07651956 Remimazolam Versus Dexmedetomidine for Sedation During Neuraxial Icahn School of Medicine at Mount Sinai Not Yet Recruiting 2026-07-28
NCT07439042 Buspirone for Anxiety in Autistic Youth Massachusetts General Hospital Not Yet Recruiting 2026-02-27
NCT06787976 Effect of Dolutegravir Compared With Darunavir/Cobicistat on the Severity of… Instituto Mexicano del Seguro Social Not Yet Recruiting 2025-06-26
NCT06896721 Effects of Nasal Administration of Dexmedetomidine on Pre-anesthesia Sedation… Fuzhou Hua Not Yet Recruiting 2025-03-26
NCT04751864 Brain Stimulation & Generalized Anxiety Study ProofPilot Active, Not Recruiting 2021-02-12
Phase 3
NCT07767903 A Trial of the Efficacy and Safety of a Fixed Dose of SEP-363856 in Adults With… Otsuka Pharmaceutical Development & Commercialization, Inc. Recruiting 2026-08-17
NCT07759128 A Trial of the Efficacy and Safety of Fixed Doses of SEP-363856 in Adults With… Otsuka Pharmaceutical Development & Commercialization, Inc. Recruiting 2026-08-12
NCT06752759 Nebulized Ketamine for the Treatment of Major Depressive Disorder Theresa Jacob, PhD, MPH Recruiting 2026-04-24
See all 1,528 active Anxiety trials with filters →

Top sponsors by active trials in this area

Massachusetts General Hospital (19) · Karolinska Institutet (14) · Istanbul University - Cerrahpasa (13) · University of California, Los Angeles (11) · The University of Hong Kong (10) · Cairo University (9) · Ohio State University (9) · Stanford University (9) · University of Regina (9) · VA Office of Research and Development (9)

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