Track this trial free. DataLookout checks ClinicalTrials.gov daily and emails you which fields changed on NCT06853431 (status, enrollment, completion dates, endpoints, sites) when this record is updated. Free accounts track up to 5 trials.

Track this trial

Determination of ED50 and ED95 With Clinical Efficacy of Intranasal Dexmedetomidine Combined With Esketamine for Preoperative Sedation in Pediatric General Anesthesia

StatusRecruiting
PhasePhase 4
Started
View on ClinicalTrials.gov ↗

Record History

See every version on ClinicalTrials.gov ↗

  1. Re-verified, no change to tracked fieldsv4
  2. Primary completion date: Jun 30, 2025 to Nov 30, 2025
    • Study completion date: Aug 1, 2025 to Nov 30, 2025
    • Secondary endpoints: 5 to 4
    • Study description expanded, about 39 words
    v3
  3. Trial status: Not Yet Recruiting to Recruiting
    • Study sites: 1 to 2
    v2
  4. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
For pediatric patients undergoing general anesthesia, poor anesthesia induction compliance often has adverse effects on individual behavior in the early postoperative period. Dexmedetomidine can reduce the cardiovascular responses and postoperative mental adverse reactions caused by esketamine anesthesia induction \[6\]. This study aims to explore the ED50 and ED95 and clinical effects of the combination of dexmedetomidine and esketamine nasal drops for preoperative sedation in children of different ages undergoing general anesthesia, providing a theoretical basis for the combined use of dexmedetomidine and esketamine for preoperative sedation in children undergoing general anesthesia.
Trial Details
NCT Number NCT06853431
Lead Sponsor Second Affiliated Hospital of Wenzhou Medical University
Conditions
(from sponsor)		 Preoperative Anxiety, Preoperative Sedation, Children, Dexmedetomidine, Esketamine, ED95, ED50, Preoperative Sedation of Children
Enrollment 80 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov