Clinical Trial

Use Muscadine Wine Nutraceuticals to Improve Brain Health, Cognition, and Mental Health

Suspended
View on ClinicalTrials.gov →
Why the trial stopped
Funding for this study was discontinued by the sponsor after the first year.
Summary
Previous studies have shown that polyphenol-rich foods can positively affect cognitive functions, memory, and mood in humans. We hypothesize that both acute and chronic intake of muscadine wine polyphenols will improve cognitive performance and mood through regulating the HPA axis, alleviating inflammation and oxidative stress, and/or inhibiting monoamine oxidase activities
Protocol Amendment History 4 changes
critical Recruitment suspended 2026-08-11
critical Recruitment suspended: Funding for this study was discontinued by the sponsor after the first year. 2026-08-11
notable Primary completion pushed: 2026-12 -> 2028-12-31 2026-08-11
minor Completion pushed: 2026-12 -> 2028-12-31 2026-08-11
Trial Details
NCT Number NCT05541887
Lead Sponsor University of Florida
Conditions Cognitive Performance, Memory, Mood, Anxiety
Enrollment 25 participants
Start Date 2023-08-30
Primary Completion 2028-12-31 (estimated)
Study Completion 2028-12-31 (estimated)
Updated on ClinicalTrials.gov 2026-08-10