Sponsor pipeline

University of North Carolina, Chapel Hill clinical trial pipeline

Get alerts when University of North Carolina, Chapel Hill's trials change

164 active trials 97 recruiting 24 disease areas 51 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-10-11

What changed in the last 30 days

24 trials changed in the last 30 days: 1 stopped, 11 with notable changes, 12 with minor changes only.

  7. Notable

    Reclassified as terminated (was completed)

    Sponsor's reason: Due to lack of resources the study was terminated.

    Also in this update: Results posted: Sep 28, 2026

    University of North Carolina, Chapel HillNot applicable NCT06979154 Registry history

    Updated

Show 12 trials with minor changes only
  2. Minor

    Completed without a posted recruiting period

    Also in this update: Final enrollment: 1750 participants (planned 1500); Primary completion date changed from estimate of Nov 30, 2026 to Aug 27, 2026

    University of North Carolina, Chapel HillNot applicable NCT07699198 Registry history

    Updated

  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.

New trial filings, last 30 days

First postedTrialPhaseStatus
2026-10-09 NCT07868536 Post-traumatic Estradiol Administration and Care Evaluation (PEACE) Phase 2 Not Yet Recruiting
2026-09-18 NCT07829133 Pilot HIV Self-Testing And Self-collected STI Testing Strategy for Sex Worker Empowerment… Not Yet Recruiting
2026-09-17 NCT07825792 Light Bulb Stimuli to Reduce Chronic Pain Not Yet Recruiting

Active trials by phase

Early Phase 1
1
Phase 1
6
Phase 1/2
1
Phase 2
11
Phase 3
2
Phase 4
13
Not charted: 130 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 164

NCT IDTitleConditionStatusUpdated
Phase 4
NCT07095361 Once Daily Intrapleural Enzyme Therapy in Complicated Parapneumonic Effusion or Empyema Pleural Infection Bacterial Recruiting 2026-09-29
NCT06312683 Rifaximin for the Secondary Prevention of Recurrent Pouchitis Pouchitis Recruiting 2026-08-03
NCT06158126 UNCPM 22314 - Pregnancy, Infant and Maternal Health Outcomes Study Pre-exposure Prophylaxis Recruiting 2026-05-05
NCT06841913 Woodsmoke Exposure, Influenza Infection, and Nasal Immunity Smoke Exposure Recruiting 2026-04-30
NCT05282277 Examining the Effects of Estradiol on Neural and Molecular Response to Reward Depression Recruiting 2026-04-29
NCT06864403 Mirikizumab in the Treatment of Chronic Inflammatory Conditions of the Pouch Pouchitis Recruiting 2026-01-30
NCT06263452 Beta-Blocker Influences on Inflammatory and Neural Responses to Stress Cardiovascular Disease Recruiting 2025-10-29
NCT06610305 Ovarian Hormone Withdrawal, Anhedonia, and Reward Sensitivity in Women With Premenstrual… Major Depressive Disorder Recruiting 2025-10-29
NCT06242795 Hypertonic Saline in NCFB Bronchiectasis Recruiting 2025-08-13
NCT07788742 Efficacy of Potassium-Competitive Acid Blockers in Barrett's Esophagus (PCAB BE Study) Barrett Esophagus Not Yet Recruiting 2026-08-26
NCT07544966 Teen Vulnerability to Irritability: Brain and Estrogen Changes Depression - Major Depressive Disorder Not Yet Recruiting 2026-08-24
NCT07756359 Tirzepatide for Ileal Pouch-anal Anastomosis (IPAA) and Chronic High Bowel Frequency… Pouch, Ileal Not Yet Recruiting 2026-08-10
NCT06352073 Dupilumab for Eosinophilic Esophagitis With Severe Strictures Eosinophilic Esophagitis Active, Not Recruiting 2026-04-29
Phase 3
NCT06179004 Supraclavicular Bupivacaine Vs. Supraclavicular Liposomal Bupivacaine for Orthopedic… Distal Radius Fractures Recruiting 2025-10-24
NCT06303739 Psilocybin-Assisted Therapy in Treatment-Resistant Depression Refractory Depression Active, Not Recruiting 2026-05-06
Phase 2
NCT07588568 A Trial of Upadacitinib for Non-responsive Eosinophilic Esophagitis EoE Recruiting 2026-10-06
NCT06636786 Prevention/Reduction of ASRs and PTSD to Sustain Civilian Performance With Sublingual… Acute Stress Reaction Recruiting 2026-09-01
NCT06059664 The EFfect of FinErenone in Kidney TransplantiOn Recipients: The EFFEKTOR Study Kidney Transplant; Complications Recruiting 2026-04-14
NCT06943404 BXCL501 After Stress to Increase Recovery Success Acute Stress Reaction Recruiting 2026-04-14
NCT07868536 Post-traumatic Estradiol Administration and Care Evaluation (PEACE) Chronic Musculoskeletal Pain Not Yet Recruiting 2026-10-09
NCT06853327 Oral Ketorolac for IUD Pain Reduction IUD Insertion Pain Enrolling by Invitation 2026-09-08
NCT06158113 Efficacy and Safety of Baricitinib in Oral Lichen Planus: a Proof-of-Concept Study Lichen Planus, Oral Active, Not Recruiting 2026-09-01
NCT05480995 Evaluation of Endometriosis With 18F-fluorofuranylnorprogesterone PET / MRI Endometriosis Active, Not Recruiting 2026-08-28
NCT07170540 UNC Cashew Sublingual Immunotherapy Cashew Nut Allergy Not Yet Recruiting 2026-04-14
NCT07526558 Mast Cell Treatment in Post-tick Bite Illness (PTBI) Post-tick Bite Illness Not Yet Recruiting 2026-04-13
See all 164 active University of North Carolina, Chapel Hill trials with filters →

Disease areas by active trials, top 10 of 24

Depression (13) · Obesity (9) · Diabetes (8) · Anxiety (6) · Cystic Fibrosis (5) · Type 2 Diabetes (5) · Crohn's Disease (4) · PTSD (4) · Dementia (3) · Type 1 Diabetes (3)

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