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Pfizer clinical trial pipeline

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251 active trials 121 recruiting 85 Phase 3 51 disease areas 156 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-09-05

What changed in the last 30 days showing 62 of 156 changes on 20 trials

2026-08-19
Trial terminated
Trial terminated: The estimated benefit-risk profile of PF-07985631 is not anticipated to be favorable in the expected population to be t...
Enrollment reduced: 76 → 9 participants
Primary completion moved earlier: 2027-08-24 → 2026-07-16
Completion moved earlier: 2027-08-24 → 2026-07-16
NCT07235150 A Study to Learn How Different Amounts of the Study Medicine Called PF-07985631 Are… · Phase 1
2026-09-04
Primary completion pushed: 2026-01-12 → 2026-10-30
Trial sites expanded: 143 → 151 locations
Completion pushed: 2026-08-31 → 2026-10-30
NCT04657991 A Clinical Trial of Three Study Medicines (Encorafenib, Binimetinib, and Pembrolizumab)… · Phase 3
2026-09-03
Primary completion pushed: 2026-09-01 → 2027-03-24
Completion pushed: 2026-09-01 → 2027-03-24
NCT05548127 TACTIVE-U: A Study to Learn About the Study Medicine (Vepdegestrant) When Given With… · Phase 1/2
2026-08-26
Primary completion pushed: 2027-11-25 → 2031-07-29
Completion pushed: 2027-11-25 → 2031-07-29
NCT06698796 A Study to Understand How the Study Medicine Dazukibart Works in People With Idiopathic… · Phase 3
2026-08-14
Primary completion pushed: 2026-12-21 → 2028-03-19
Primary endpoint(s) modified
Enrollment reopened
Enrollment increased: 550 → 1330 participants
Trial sites expanded: 143 → 147 locations
Completion pushed: 2026-12-21 → 2028-03-19
Trial arms changed: 4 → 5
NCT06873945 A Study of 2 Doses of Ritlecitinib in People 12 Years of Age and Older With Alopecia… · Phase 3
2026-08-12
Primary completion pushed: 2026-07-13 → 2026-12-28
Trial sites reduced: 230 → 224 locations
NCT06551324 A Study to Learn About the Investigational Medicine Called PF-06821497 (Mevrometostat) in… · Phase 3
2026-08-25
Primary completion pushed: 2026-06-30 → 2027-05-13
Enrollment closed, study ongoing
Trial sites expanded: 38 → 41 locations
Completion pushed: 2026-06-30 → 2027-05-13
NCT06294925 A Study to Learn About the Effectiveness of Etrasimod in People With Ulcerative Colitis
2026-08-14
Primary completion pushed: 2025-07-07 → 2026-03-11
NCT05675449 A Clinical Trial of Four Medicines (Elranatamab Plus Carfilzomib and Dexamethasone or… · Phase 1
2026-08-22
Primary completion pushed: 2026-06-30 → 2026-09-30
Completion pushed: 2026-06-30 → 2026-09-30
NCT07494656 A Retrospective Observational Study of Epidemiology and Outcomes in Transthyretin Amyloid…
2026-08-15
Primary completion pushed: 2025-11-30 → 2026-05-29
Enrollment reduced: 1200 → 937 participants
Completed without a posted recruiting period
Trial sites expanded: 0 → 7 locations
Completion pushed: 2025-11-30 → 2026-05-29
NCT07089680 A Study to Learn About the Study Medicine Paxlovid (Nirmatrelvir + Ritonavir) in Adults…
2026-08-26
Primary endpoint(s) modified
Primary completion pushed: 2026-07-31 → 2026-09-30
Completion pushed: 2026-07-31 → 2026-09-30
NCT07251465 A Study to Learn How Effective is PCV20 to Help Stop Adults Who Have a Higher Chance of…
2026-08-18
Enrollment reduced: 54 → 48 participants
Trial completed
Primary completion moved earlier: 2026-09-18 → 2026-07-02
Completion moved earlier: 2026-09-18 → 2026-07-08
NCT07400679 A Study to Learn How the Study Medicine Called PF-08653944 is Taken up Into the Blood in… · Phase 1
2026-09-05
Recruitment opened
Interventions modified
Trial sites expanded: 0 → 3 locations
NCT07765888 A Study to Learn About the Study Medicine Called Tilrekimig in People With… · Phase 3
2026-09-05
Trial completed
NCT07594769 A Study to Compare the Blood Levels of Two Dosage Formulations of the Study Medicine in… · Phase 1
2026-09-05
Recruitment opened
NCT07792941 A Study to Learn About the Single Dose Pharmacokinetics of Study Medicine Called… · Phase 1
2026-09-02
Enrollment closed, study ongoing
Trial sites reduced: 71 → 67 locations
Final enrollment: 128 participants (planned 240)
Primary completion moved earlier: 2027-03-05 → 2026-12-08
Completion moved earlier: 2027-04-02 → 2027-01-05
NCT07228390 A 16-Week Study to Learn About the Study Medicine Called Ritlecitinib in Adults With Long… · Phase 2
2026-09-05
Enrollment closed, study ongoing
Final enrollment: 1 participants — under 1% of the 553 planned
NCT07459686 An Observational Study to Learn About Velsipity After Long Term Use in Patients With…
2026-09-02
Enrollment closed, study ongoing
Trial sites reduced: 83 → 66 locations
Final enrollment: 148 participants (planned 124)
Completion moved earlier: 2029-06-18 → 2027-08-31
NCT05538130 A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in… · Phase 1
2026-09-02
Enrollment closed, study ongoing
Final enrollment: 103 participants (planned 267)
Primary completion moved earlier: 2028-04-23 → 2027-08-31
Completion moved earlier: 2029-10-25 → 2027-08-31
NCT05355701 A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced… · Phase 1
2026-09-01
Trial completed
Enrollment increased: 15 → 30 participants
NCT07587697 A Study to Compare the Amount of Two Forms of Tafamidis in the Blood of Healthy Adults… · Phase 1

New trial filings, last 30 days

First postedTrialPhaseStatus
2026-08-31 NCT07794748 A Study to Assess the Safety, Tolerability, and Immunogenicity of 3 Lots of a Multivalent… Phase 3 Not Yet Recruiting
2026-08-31 NCT07794761 A Study to Learn About Safety and Effects of Once-weekly Treatment With Berobenatide in… Phase 3 Not Yet Recruiting
2026-08-31 NCT07794774 A Study to Learn About Safety and Effects of Once-monthly Treatment With Berobenatide in… Phase 3 Not Yet Recruiting
2026-08-28 NCT07792941 A Study to Learn About the Single Dose Pharmacokinetics of Study Medicine Called… Phase 1 Recruiting
2026-08-28 NCT07792954 A Study to Learn About the Study Medicine Called PF-08653944 Taken Once-Weekly Compared… Phase 3 Not Yet Recruiting
2026-08-24 NCT07782450 A Study to Learn About a Medicine Called PF-08154225 in Participants With Autoimmune… Phase 1/2 Not Yet Recruiting
2026-08-24 NCT07783425 A Study to Learn About the Study Medicine Called Tilrekimig in People With Moderate-to… Phase 3 Not Yet Recruiting
2026-08-21 NCT07779590 A Study to Learn About the Outcomes Between Study Medicines, Enzalutamide and… Not Yet Recruiting
2026-08-19 NCT07772921 A Study to Learn About the Study Medicine Called Tilrekimig in People With Severe Asthma Phase 3 Not Yet Recruiting
2026-08-17 NCT07768163 A Study to Learn About the Safety of PENBRAYA During Pregnancy Recruiting

Active trials by phase

Phase 1
46
Phase 1/2
13
Phase 2
34
Phase 2/3
5
Phase 3
80
Phase 4
9
Not charted: 64 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 251

NCT IDTitleConditionStatusUpdated
Phase 4
NCT06952660 Ocular Assessments in Patients Treated With Tivdak® in Recurrent or Metastatic Cervical… Cervical Cancer Recruiting 2026-09-04
NCT07609914 A Study to Learn About the Safety of Taking an Additional Dose of the Medicine Rimegepant… Acute Treatment of Migraine Recruiting 2026-08-24
NCT07685769 A Study to Find Out if the Medicine Called Rimegepant is Safe for Adults in India Acute Treatment of Migraine Recruiting 2026-08-21
NCT06057402 Elranatamab Post Trial Access Study for Participants With Multiple Myeloma (MM) Multiple Myeloma Recruiting 2026-07-01
NCT05203172 The FLOTILLA Study: Providing Continued Access to The Study Medicines Encorafenib and… Solid Tumors Recruiting 2026-04-07
NCT07768358 Tucatinib Continuation Study HER2-positive Breast Cancer Not Yet Recruiting 2026-08-28
NCT05144997 Lorlatinib Continuation Study Non-Small-Cell Lung Cancer Active, Not Recruiting 2026-08-26
NCT05295290 A Study to Learn About The COVID-19 (Study) Vaccine (Called COMIRNATY) in People That Are… Myocarditis Active, Not Recruiting 2026-05-07
NCT05160922 Crizotinib Continuation Clinical Study NSCLC Active, Not Recruiting 2026-03-30
Phase 3
NCT06807268 A Study of the Medicine Called Abrocitinib in Children 6 to Less Than 12 Years of Age… Eczema Recruiting 2026-09-04
NCT06807281 A Long-term Study of the Medicine Called Abrocitinib in Children Aged 2 Years and Older… Atopic Dermatitis Recruiting 2026-09-04
NCT07144280 A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel… Non-small Cell Carcinoma Recruiting 2026-09-04
NCT07595549 A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People… Obesity Recruiting 2026-09-04
NCT07765888 A Study to Learn About the Study Medicine Called Tilrekimig in People With… Atopic Dermatitis Recruiting 2026-09-04
NCT07660198 Study to Learn About Safety, Tolerability, and Immune Response of a Catch-up Pneumococcal… Pneumococcal Disease Recruiting 2026-08-31
NCT06698796 A Study to Understand How the Study Medicine Dazukibart Works in People With Idiopathic… Dermatomyositis Recruiting 2026-08-25
NCT07013474 A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are… COVID-19 Infection Recruiting 2026-08-25
NCT05020236 A Study to Learn About the Study Medicine Elranatamab Alone and With Daratumumab in… Multiple Myeloma Recruiting 2026-08-24
NCT05156398 Efficacy and Safety Study of Rimegepant for the Preventative Treatment of Migraine in… Migraine Recruiting 2026-08-24
NCT05623020 A Study to Learn About the Effects of the Combination of Elranatamab, Daratumumab and… Multiple Myeloma Recruiting 2026-08-24
NCT06152575 MagnetisMM-32: A Study to Learn About the Study Medicine Called Elranatamab in People… Multiple Myeloma Recruiting 2026-08-24
NCT06629779 A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic… Metastatic Castration-Resistant Prostate Cancer Recruiting 2026-08-24
NCT07160244 BEATRIX: A Study to Learn About a Group B Streptococcus Vaccine in Healthy Pregnant Women… Healthy Recruiting 2026-08-24
NCT07733765 A Study in Young People and Adults to Learn About the Medicine Ritlecitinib for Treatment… Alopecia Areata Recruiting 2026-08-24
NCT07222566 Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in… Advanced Non-Small Cell Lung Cancer Recruiting 2026-08-17
See all 251 active Pfizer trials with filters →

Disease areas by active trials, top 10 of 51

Breast Cancer (31) · Non-Small Cell Lung Cancer (NSCLC) (28) · Lung Cancer (21) · Migraine (13) · Atopic Dermatitis (12) · Obesity (12) · Multiple Myeloma (11) · Colorectal Cancer (10) · Prostate Cancer (10) · Bladder Cancer (7)

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