154 active trials 89 recruiting 40 disease areas 12 changes in 30 days
7 trials changed in the last 30 days: 0 stopped, 3 with notable changes, 4 with minor changes only.
Primary completion pushed from Dec 2026 to Dec 2027
Also in this update: Recruitment opened; Completion pushed from Dec 2026 to Jun 2028
Imperial College LondonNot applicable NCT06611306 Registry history of NCT06611306 on ClinicalTrials.gov (opens the registry)
Updated
Primary endpoint(s) modified
Imperial College LondonNot specified NCT07057466 Registry history of NCT07057466 on ClinicalTrials.gov (opens the registry)
Updated
Phase changed: not specified → not applicable
Also in this update: Completed without a posted recruiting period; Final enrollment: 7200 participants (planned 8400)
Imperial College LondonNot applicable NCT06144580 Registry history of NCT06144580 on ClinicalTrials.gov (opens the registry)
Updated
Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Not Yet Recruiting
Imperial College LondonNot specified NCT06619223 Registry history of NCT06619223 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Recruiting
Imperial College LondonNot applicable NCT06091475 Registry history of NCT06091475 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Sep 2023); last known: Not Yet Recruiting
Imperial College LondonNot specified NCT06063304 Registry history of NCT06063304 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Active, Not Recruiting
Imperial College LondonNot applicable NCT02487654 Registry history of NCT02487654 on ClinicalTrials.gov (opens the registry)
Changed
Registry verification sweep
Changed
| First posted | Trial | Phase | Status |
|---|---|---|---|
| 2026-10-08 | NCT07865364 Coronary Sinus Reducer Objective Impact on SymptoMs, Ischaemia and miCrovascular… | Not Yet Recruiting | |
| 2026-09-22 | NCT07833488 Exploring Factors Linked to Worsening Over Time in People With Early-stage Knee… | Not Yet Recruiting |
| Early Phase 1 | 1 | |
| Phase 1 | 4 | |
| Phase 1/2 | 1 | |
| Phase 2 | 15 | |
| Phase 3 | 3 | |
| Phase 4 | 1 |
| NCT ID | Title | Condition | Status | Updated |
|---|---|---|---|---|
| Phase 4 | ||||
| NCT05735639 | THRomboprophylaxis in Individuals Undergoing Superficial endoVEnous Treatment (THRIVE) | Venous Thromboembolism | Recruiting | 2026-06-04 |
| Phase 3 | ||||
| NCT05889507 | Cooling in Mild Encephalopathy | Neonatal Encephalopathy | Recruiting | 2026-02-06 |
| NCT05395195 | Erythropoietin for Neonatal Encephalopathy in LMIC (EMBRACE Trial) | Encephalopathy | Recruiting | 2024-03-19 |
| NCT05085028 | A Randomised Open-label Phase III Trial of REduced Frequency Pembrolizumab immuNothErapy… | Lung Cancer, Nonsmall Cell | Recruiting | 2024-03-07 |
| Phase 2 | ||||
| NCT07682233 | Role of a Mitochondrial Receptor in Blood Sugar Regulation | Heathly Volunteers | Recruiting | 2026-07-02 |
| NCT06355583 | Intestinal Microbiota Transplant Prior to Allogeneic Stem Cell Transplant (MAST) Trial | Acute Lymphoblastic Leukaemia | Recruiting | 2025-04-17 |
| NCT04319367 | A Randomised Placebo Controlled Trial of ART Plus Dual Long-acting HIV-specific Broadly… | HIV/AIDS and Infections | Recruiting | 2024-04-17 |
| NCT07737522 | Myocardial Metabolic Flux in Pulmonary Arterial Hypertension | Pulmonary Arterial Hypertension | Not Yet Recruiting | 2026-07-30 |
| NCT05109169 | METformin and FINGER Intervention to Prevent Cognitive Impairment and Disability in Older… | Cognitive Decline | Active, Not Recruiting | 2026-07-10 |
| NCT06230354 | Explore the Efficacy and Mechanism of Action of Tezepelumab in Eosinophilic… | EGPA - Eosinophilic Granulomatosis With Polyangiitis | Active, Not Recruiting | 2026-04-29 |
| NCT07112352 | Healthy Ageing: a Feasibility Study to Evaluate Digitally-enabled Ways to Support Healthy… | Frailty | Active, Not Recruiting | 2026-03-25 |
| NCT07389031 | Maralixibat for Intrahepatic Cholestasis of Pregnancy | Intrahepatic Cholestasis of Pregnancy | Not Yet Recruiting | 2026-02-05 |
| NCT06232564 | A Study of Etoposide-carboplatin in Combination With Pembrolizumab and Lenvatinib… | Neuroendocrine Tumors | Active, Not Recruiting | 2026-01-14 |
| NCT07295834 | Modafinil For Fatigue in IBD: A Feasibility Randomised Controlled Trial | Crohn Disease (CD) | Not Yet Recruiting | 2025-12-22 |
| NCT07191821 | TSPO Modulation in AD | Alzheimer s Disease | Enrolling by Invitation | 2025-10-01 |
| NCT07200622 | Oral Semaglutide in Patients With Alzheimer's Disease | Alzheimer Disease | Not Yet Recruiting | 2025-10-01 |
| NCT07172815 | PDE5 Inhibitor for Alzheimer's Disease | Alzheimer Disease | Not Yet Recruiting | 2025-09-15 |
| NCT03763253 | Additional Treatments to the Local Tumour for Metastatic Prostate Cancer: Assessment of… | Prostate Cancer | Active, Not Recruiting | 2025-02-07 |
| NCT05318794 | Neoadjuvant Systemic and Peritoneal Chemotherapy for Advanced Gastric Cancer | Gastric Cancer | Not Yet Recruiting | 2023-09-13 |
| Phase 1/2 | ||||
| NCT03991780 | Fostamatinib in the Treatment of Chronic Active Antibody Mediated Rejection | Renal Transplant Rejection | Active, Not Recruiting | 2024-11-25 |
| Phase 1 | ||||
| NCT07397455 | Development of a Controlled Human Infection Model for Assessment of SARS-CoV-2 Omicron… | SARS-CoV-2 (COVID-19) | Recruiting | 2026-07-17 |
| NCT05178693 | Lutathera and ASTX727 in Neuroendocrine Tumours | Neuroendocrine Tumors | Recruiting | 2025-11-24 |
| NCT07697183 | TSPO Endothelial - EMPATHY | PAH | Enrolling by Invitation | 2026-07-13 |
| NCT05646082 | Preliminary Assessment of Safety and Tolerability of Dostarlimab in Combination… | Refractory HIV Associated Kaposi Sarcoma | Active, Not Recruiting | 2026-03-31 |
| Early Phase 1 | ||||
| NCT06798636 | PsiloIMAGINE: A Psychedelic-augmented Mental Imagery-based Intervention for Young People… | Self Harm | Recruiting | 2025-12-05 |
Diabetes (11) · Colorectal Cancer (9) · Heart Disease (8) · Esophageal Cancer (7) · Gastric Cancer (7) · Hypertension (6) · Prostate Cancer (6) · Type 2 Diabetes (6) · Alzheimer's Disease (5) · Coronary Artery Disease (5)