Sponsor Pipeline

Alliance for Clinical Trials in Oncology Clinical Trial Pipeline

Data updated daily from ClinicalTrials.gov — last refresh 2026-08-16
70
Active Trials
27
Recruiting
39
Phase 3
10
Disease Areas
18
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-08-06 NCT06661720
Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab)…
Trial sites expanded: 415 -> 421 locations
2026-08-06 NCT02523014
Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients…
Trial sites expanded: 780 -> 783 locations
2026-08-06 NCT07321652
Testing the Addition of Anti-Cancer Drug Sonrotoclax, to the Standard Treatment…
Trial sites expanded: 152 -> 182 locations
2026-08-06 NCT07200830
Testing Different Dosing Schedules of the Anti-cancer Drug, Lutetium 177Lu PSMA RLT and…
Trial sites expanded: 102 -> 112 locations
2026-08-06 NCT07143487
Family Communications After Genetic Testing
Trial sites expanded: 276 -> 299 locations
2026-08-06 NCT06632327
Comparing Impact of Treatment Before or After Surgery in Patients With Stage II-IIIB…
Trial sites expanded: 382 -> 415 locations
2026-08-06 NCT06876714
ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+…
Trial sites expanded: 671 -> 684 locations
2026-08-06 NCT06931340
Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy…
Trial sites expanded: 195 -> 200 locations
2026-08-06 NCT07283939
Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned…
Trial sites expanded: 344 -> 363 locations
2026-08-06 NCT05812807
Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a…
Trial sites expanded: 842 -> 846 locations
2026-08-06 NCT07215910
Testing Addition of an Anti-cancer Drug, Vorasidenib to Temozolomide, After Radiation for…
Trial sites expanded: 82 -> 97 locations
2026-08-06 NCT07293247
A Study of Targeted Post-Surgery Radiation Therapy for Non-Small Cell Lung Cancer With…
Trial sites expanded: 33 -> 74 locations
2026-08-02 NCT00899223
Collecting and Storing Blood, Bone Marrow, and Other Samples From Patients With Acute…
overall status: Active, Not Recruiting → Unknown
2026-07-31 NCT04939090
Olanzapine Versus Megestrol Acetate for the Treatment of Loss of Appetite Among Advanced…
date change Primary completion moved earlier: 2027-04-01 -> 2026-04-14
2026-07-31 NCT04939090
Olanzapine Versus Megestrol Acetate for the Treatment of Loss of Appetite Among Advanced…
date change Completion moved earlier: 2027-12-31 -> 2026-12-31
2026-07-24 NCT01901094
Comparison of Axillary Lymph Node Dissection With Axillary Radiation for Patients With…
date change Primary completion pushed: 2026-01-01 -> 2031-01-31
2026-07-24 NCT01901094
Comparison of Axillary Lymph Node Dissection With Axillary Radiation for Patients With…
date change Completion pushed: 2026-01-01 -> 2031-01-31
2026-07-23 NCT04114981
Single Fraction Stereotactic Radiosurgery Compared With Fractionated Stereotactic…
date change Primary completion moved earlier: 2026-09-01 -> 2025-12-14
Active Trials by Phase
Phase 3
35
Phase 2/3
4
Phase 2
17
Phase 1/2
1
Not specified
13
Active Trials — top 25 of 70
NCT IDTitleConditionStatus
Phase 3
NCT05379153 Testing Laser Therapy for Treatment of Vaginal Dryness in Survivors of Breast Cancer, The… Anatomic Stage 0 Breast Cancer AJCC v8 Recruiting
NCT06992427 High-dose Prophylactic Gabapentin (HOPE) vs. Placebo to Prevent Opioid Use for Oral… Head and Neck Squamous Cell Carcinoma Recruiting
NCT03150693 Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly… B Acute Lymphoblastic Leukemia Recruiting
NCT05008848 Reaching Rural Cancer Survivors Who Smoke Using Text-Based Program Cigarette Smoking-Related Carcinoma Recruiting
NCT05673148 Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for… Metastatic Colorectal Adenocarcinoma Recruiting
NCT05677490 mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced… Advanced Esophageal Adenocarcinoma Recruiting
NCT05812807 Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a… Anatomic Stage II Breast Cancer AJCC v8 Recruiting
NCT06632327 Comparing Impact of Treatment Before or After Surgery in Patients With Stage II-IIIB… Resectable Lung Non-Small Cell Carcinoma Recruiting
NCT06661720 Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab)… Clear Cell Renal Cell Carcinoma Recruiting
NCT06876714 ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+… Anatomic Stage I Breast Cancer AJCC v8 Recruiting
NCT06931340 Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy… Castration-Sensitive Prostate Carcinoma Recruiting
NCT07000084 Testing the Addition of an Anti-Cancer Drug, Gemcitabine, to Usual Treatment (BCG Alone)… Recurrent Non-Muscle Invasive Bladder Carcinoma Recruiting
NCT07200830 Testing Different Dosing Schedules of the Anti-cancer Drug, Lutetium 177Lu PSMA RLT and… Metastatic Castration-Resistant Prostate Carcinoma Recruiting
NCT07215910 Testing Addition of an Anti-cancer Drug, Vorasidenib to Temozolomide, After Radiation for… Astrocytoma, IDH-Mutant, Grade 3 Recruiting
NCT07321652 Testing the Addition of Anti-Cancer Drug Sonrotoclax, to the Standard Treatment… Chronic Lymphocytic Leukemia Recruiting
NCT05976763 Testing Continuous Versus Intermittent Treatment With the Study Drug Zanubrutinib for… Mantle Cell Lymphoma Recruiting
NCT00430183 Surgery With or Without Docetaxel and Leuprolide or Goserelin in Treating Patients With… Prostate Cancer Active, Not Recruiting
NCT02750826 Breast Cancer WEight Loss Study (BWEL Study) Breast Carcinoma Active, Not Recruiting
NCT04711109 Studying the Effect of Denosumab on Preventing Breast Cancer in Women With a BRCA1… BRCA1 Mutation Active, Not Recruiting
NCT04989504 Testing the Application of Mepitel Film During Radiation Therapy to Reduce Radiation… Breast Carcinoma Active, Not Recruiting
NCT04379570 Additional Support Program Via Text Messaging and Telephone-Based Counseling for Breast… Anatomic Stage I Breast Cancer AJCC v8 Active, Not Recruiting
NCT00887146 Radiation Therapy With Concomitant and Adjuvant Temozolomide Versus Radiation Therapy… Brain and Central Nervous System Tumors Active, Not Recruiting
NCT04455750 A Clinical Study Evaluating The Benefit of Adding Rucaparib to Enzalutamide for Men With… Castration-Resistant Prostate Carcinoma Active, Not Recruiting
NCT04340141 Testing the Use of the Usual Chemotherapy Before and After Surgery for Removable… Pancreatic Adenosquamous Carcinoma Active, Not Recruiting
NCT03414970 Hypofractionated Radiation Therapy After Mastectomy in Preventing Recurrence in Patients… Ductal Breast Carcinoma Active, Not Recruiting
See all 70 active Alliance for Clinical Trials in Oncology trials with filters →
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