| Detected | Trial | Change |
|---|---|---|
| 2026-06-12 | NCT06814938 A Study of a Novel Precision Medicine Approach For Obesity |
overall status: "Recruiting" → "Active Not Recruiting" |
| 2026-06-12 | NCT07417631 Emulation of the REWIND Cardiovascular Outcomes Trial in Healthcare Claims Data. |
Primary endpoint(s) modified |
| 2026-06-12 | NCT07417631 Emulation of the REWIND Cardiovascular Outcomes Trial in Healthcare Claims Data. |
Enrollment increased: 30000 -> 300000 participants |
| 2026-06-12 | NCT07417631 Emulation of the REWIND Cardiovascular Outcomes Trial in Healthcare Claims Data. |
date change Primary completion pushed: 2026-03 -> 2026-06-15 |
| 2026-06-12 | NCT07417631 Emulation of the REWIND Cardiovascular Outcomes Trial in Healthcare Claims Data. |
date change Completion pushed: 2026-03 -> 2026-06-15 |
| 2026-06-12 | NCT06184568 A Study Comparing IBI362 vs Semaglutide in Chinese Adults With Early Type 2 Diabetes and… |
Trial completed |
| 2026-06-12 | NCT06184568 A Study Comparing IBI362 vs Semaglutide in Chinese Adults With Early Type 2 Diabetes and… |
date change Completion moved earlier: 2026-06-30 -> 2026-02-09 |
| 2026-06-11 | NCT07462663 SHAPE-ENDO: Pilot Randomized Trial of Multimodal Pre-Surgical Optimization Versus… |
Primary endpoint(s) modified |
| 2026-06-11 | NCT07462663 SHAPE-ENDO: Pilot Randomized Trial of Multimodal Pre-Surgical Optimization Versus… |
Trial arms changed: 1 -> 2 |
| 2026-06-11 | NCT07462663 SHAPE-ENDO: Pilot Randomized Trial of Multimodal Pre-Surgical Optimization Versus… |
date change Primary completion pushed: 2027-05 -> 2031-04 |
| 2026-06-11 | NCT07462663 SHAPE-ENDO: Pilot Randomized Trial of Multimodal Pre-Surgical Optimization Versus… |
date change Completion pushed: 2028-09 -> 2035-01 |
| 2026-06-06 | NCT07319286 Role of Glucagon-like Peptide-1 Receptor Agonists in Menstrual Irregularities in… |
date change Primary completion pushed: 2026-04 -> 2026-12 |
| 2026-06-06 | NCT07319286 Role of Glucagon-like Peptide-1 Receptor Agonists in Menstrual Irregularities in… |
date change Completion pushed: 2026-08 -> 2027-03 |
| 2026-06-06 | NCT05356104 GLP-1 Analogue in Preventing Progression of Small Vessel Disease (GAPP-SVD) |
date change Primary completion pushed: 2026-05 -> 2027-05 |
| 2026-06-06 | NCT05356104 GLP-1 Analogue in Preventing Progression of Small Vessel Disease (GAPP-SVD) |
date change Completion pushed: 2026-12 -> 2027-12 |
| 2026-05-30 | NCT07564414 A Research Study to Look at How Two Different Doses of CagriSema and One Dose of… |
Recruitment opened |
| 2026-05-29 | NCT07297238 Effect of GLP-1 on Intestinal Barrier Function in SBS-IF Patients: A Preliminary… |
date change Completion pushed: 2026-05-31 -> 2026-06-30 |
| 2026-05-28 | NCT05202353 A Study in People With Obesity to Test the Effects of BI 456906 Compared With Semaglutide… |
date change Completion pushed: 2026-12-01 -> 2027-01-01 |
| 2026-05-27 | NCT07221214 GLP-1 Receptor Agonists to Decrease Ethanol and CVD Risk in HIV |
date change Primary completion pushed: 2029-07-31 -> 2029-10-31 |
| 2026-05-27 | NCT07221214 GLP-1 Receptor Agonists to Decrease Ethanol and CVD Risk in HIV |
date change Completion moved earlier: 2030-07-31 -> 2030-01-31 |
| First Posted | Trial | Phase | Status |
|---|---|---|---|
| 2026-06-11 | NCT07642635 Glucagon-Like Peptide-1 Receptor Agonists to Attenuate Metabolic Risk in Individuals With… | Phase 1/2 | Not Yet Recruiting |
| 2026-06-10 | NCT07639021 A Research Study Comparing Different Ways of Increasing the Dose of NNC0662-0419 in… | Phase 2 | Not Yet Recruiting |
| 2026-06-05 | NCT07628556 Antidiabetic Medications and Risk of Cancer | Completed | |
| 2026-06-05 | NCT07628985 BALANCE-DM2 Study of Bofanglutide in Adults With Type 2 Diabetes | Phase 3 | Not Yet Recruiting |
| 2026-06-04 | NCT07627074 Weight Loss in Adults Using Semaglutide (Real-world Study) | Recruiting | |
| 2026-06-04 | NCT07627191 GLP-1 RA Plus SOC Treatment in First-line, Metastatic Pancreatic, Colorectal, or… | Early Phase 1 | Not Yet Recruiting |
| 2026-06-03 | NCT07622810 BALANCE-OBS: Bofanglutide (GZR18) Versus Semaglutide in Latin American Adults With… | Phase 3 | Not Yet Recruiting |
| 2026-06-02 | NCT07619495 Injectable Semaglutide vs Dulaglutide in Individuals at Cardiovascular Risk | Active, Not Recruiting | |
| 2026-06-02 | NCT07619508 Tirzepatide vs Semaglutide in Individuals at Cardiovascular Risk But Without Diabetes. | Active, Not Recruiting | |
| 2026-06-02 | NCT07621419 Study of Adult Patients Residing in Argentina Diagnosed With Type 2 Diabetes Treated With… | Recruiting |
| NCT ID | Title | Condition | Status |
|---|---|---|---|
| Phase 4 | |||
| NCT05702931 | Semaglutide Treatment for Hyperglycaemia After Renal Transplantation | Hyperglycemia | Recruiting |
| NCT07314684 | GLP1-RAs Effects on Inflammatory and Endothelial Biomarkers in T2DM | T2DM (Type 2 Diabetes Mellitus) | Recruiting |
| NCT07242534 | Effect of Semaglutide on Embryo Quality in Overweight and Obese Patients Undergoing In… | Infertility | Recruiting |
| NCT06132477 | Impact GLP-1 Agonists Following Bariatric | Morbid Obesity | Recruiting |
| NCT07136714 | Does Semaglutide Improve Depressive Symptoms in Patients With Major Depressive Disorder… | Major Depressive Disorder | Recruiting |
| NCT07401992 | Effects of Semaglutide on Clinical Outcomes and Metabolic Inflammation in Psoriasis | Psoriasis (PsO) | Recruiting |
| NCT06396416 | Obesity Management for Kidney TRANSPLANTation: OK-TRANSPLANT 2 | Obesity | Recruiting |
| NCT07213466 | Individualized Pharmacological Approach to Obesity in Patients With Bipolar Disorder | Bipolar I Disorder | Recruiting |
| NCT05119179 | Pharmacogenetics of the Response to GLP-1 in Mexican-Americans With Prediabetes | PreDiabetes | Recruiting |
| NCT07272343 | The Impact of Semaglutide Compared to Energy Restriction on Type 2 Diabetes | Type 2 Diabetes Mellitus (T2DM) | Recruiting |
| NCT06003153 | GLUCOSE-MGH: Genetic Links Understood Through Challenge With Oral Semaglutide Exposure at… | Genetic Predisposition | Recruiting |
| NCT05390892 | PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes | Type2Diabetes | Recruiting |
| NCT06706284 | Glycemic and Weight Loss Effects of GLP-1R Agonist Therapy in Subjects With Spinal Cord… | Spinal Cord Injuries | Recruiting |
| NCT05482789 | Exenatide Pharmacokinetics and Pharmacodynamics in Gestational Diabetes | Gestational Diabetes | Recruiting |
| NCT06613854 | Effect of Early Combination Antihyperglycemic Treatment on Metabolic Control in… | Type 2 Diabetes Mellitus (T2DM) | Recruiting |
| NCT07558863 | Effect of GLP-1RA on Cardiac Autonomic Neuropathy in Type 2 Diabetes | Type 2 Diabetes | Recruiting |
| NCT06324461 | GLP-1 Receptor Agonist for Reduction of Myocardial Injury After Non-cardiac Surgery | Myocardial Injury | Recruiting |
| NCT07178145 | Epicardial Adipose Tissue Composition and Heart Failure With Preserved Ejection Fraction | Heart Failure Preserved Ejection Fraction | Recruiting |
| NCT06801015 | Effects of Long-Acting GLP-1 (Glucagon-like Peptide-1) or Dual Incretin (GLP-1 and GIP… | Obesity | Active, Not Recruiting |
| NCT07325435 | Beta Cell Function in Type 2 Diabetes: Differential Effects of SGLT2 Inhibitors and… | Type 2 Diabetes (T2DM) | Active, Not Recruiting |
| NCT06042153 | DIALYSIS-TIR Study | Type 2 Diabetes | Active, Not Recruiting |
| NCT06977438 | Promoting Healthy Children and Youth | Obesity, Childhood | Not Yet Recruiting |
| NCT07389941 | Semaglutide PrIor to CathEeter Ablation in Patients With Atrial Fibrillation | Atrial Fibrillation (AF) | Not Yet Recruiting |
| NCT06851962 | Impact of Pharmacogenetic-Guided Treatment on Type 2 Diabetes. | Diabetes Mellitus Type 2 | Active, Not Recruiting |
| NCT07483801 | DECODE - Haemodynamic Effects Of Semaglutide and Tirzepatide - a Series of Pilot Studies | Cardiovascular Diseases | Not Yet Recruiting |