Disease landscape

Type 1 Diabetes clinical trials

Get alerts when Type 1 Diabetes trials change

449 active trials 248 recruiting 22 Phase 3 284 sponsors 61 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-08-28

What changed in the last 30 days showing 43 of 61 changes on 19 trials

2026-08-27
Trial terminated
Trial terminated: Stopped for futility.
Primary completion moved earlier: 2027-12 → 2026-06-24
Completion moved earlier: 2027-12 → 2026-06-24
NCT05018585 A Phase III Study to Investigate if the Study Drug Diamyd Can Preserve Insulin Production… · Diamyd Medical AB · Phase 3
2026-08-06
Withdrawn before enrolling
Trial withdrawn: Changed IRB number
Enrollment reduced: 70 → 0 participants
Primary completion moved earlier: 2028-08 → 2026-07-31
Completion moved earlier: 2028-08 → 2026-07-31
NCT05985135 Impact of Insulin Deprivation and Hyperglycemia on Plasma Protein Synthesis in People… · Mayo Clinic
2026-07-31
Trial terminated
Trial terminated: Recruitment.
Primary completion pushed: 2025-12 → 2026-07-20
Enrollment reduced: 100 → 33 participants
Completion pushed: 2025-12 → 2026-07-20
NCT06786130 Societal Burden Associated With Type 1 Diabetes in Canada · PeriPharm
2026-08-28
Primary completion pushed: 2028-05 → 2029-02
Completion pushed: 2028-08 → 2030-02
NCT07325201 Mitigating DKA in Type 1 Diabetes for Safe Use of SGLT Inhibitors Using Dual Continuous… · HealthPartners Institute · Phase 2
2026-08-25
Primary endpoint(s) modified
NCT07187531 SAFety and Efficacy of Human Anti-thymocyte ImmunoGlobUlin SAB-142 ARresting Progression… · SAb Biotherapeutics, Inc. · Phase 2
2026-08-21
Primary completion pushed: 2025-11-30 → 2026-11-30
NCT05515939 Evaluating the InPen in Pediatric Type 1 Diabetes · Wayne State University
2026-08-19
Primary completion pushed: 2026-07-01 → 2027-07-01
NCT06057662 Personalized Comprehensive Diabetes Support for Children With Newly Diagnosed Type 1… · University of California, Davis
2026-08-18
Primary completion pushed: 2026-06-30 → 2026-10-30
Completion pushed: 2026-06-30 → 2026-10-30
NCT06640478 A 12-week Pilot Nutrition Intervention for Children With New Diagnosis of Stage 3 Type 1… · Milton S. Hershey Medical Center
2026-08-14
Primary completion pushed: 2026-06 → 2026-12
Enrollment closed, study ongoing
Completion pushed: 2026-06 → 2026-12
NCT07212790 REAL-Fam Feasibility Study for Youth Diabetes Management · University of North Carolina, Chapel Hill
2026-08-13
Primary completion pushed: 2026-08 → 2027-02
Completion pushed: 2026-08 → 2027-02
NCT07226583 Using a Personalized Decision Support Tool to Help People With Type 1 Diabetes Manage… · Stanford University
2026-08-13
Primary completion pushed: 2026-06 → 2026-12
Completion pushed: 2026-06 → 2026-12
NCT06908057 Accessing Care, Clinical Trials and Screening for Underserved Children and Adults With… · AdventHealth Translational Research Institute
2026-08-05
Primary completion pushed: 2026-08-25 → 2027-08-25
Completion pushed: 2026-09-25 → 2027-09-25
NCT07099482 "Ultrasound-Enhanced Propolis Therapy for Healing Diabetic Foot Wounds" · Sinai University
2026-08-28
Primary endpoint(s) modified
Trial completed
Completion moved earlier: 2026-04-30 → 2025-12-21
Results posted: 2026-08-27
NCT04506151 Sleep Optimization to Improve Glycemic Control in Adults With Type 1 Diabetes · University of Illinois at Chicago
2026-08-20
Primary endpoint(s) modified
NCT07325201 Mitigating DKA in Type 1 Diabetes for Safe Use of SGLT Inhibitors Using Dual Continuous… · HealthPartners Institute · Phase 2
2026-08-28
Recruitment opened
NCT07766811 Pilot Implementation Trial of Implementation Toolkits for Diabetes Coaching · Nemours Children's Clinic
2026-08-11
Recruitment opened
NCT06820281 Acute Metabolic Effects of Tirzepatide in Type 1 Diabetes · Victor Chang Cardiac Research Institute · Phase 2
2026-08-14
Recruitment opened
NCT07427251 The Postprandial Hypo-Avoid Study · Steno Diabetes Center Copenhagen · Phase 4
2026-08-12
Enrollment closed, study ongoing
NCT06305286 Safety, Tolerability, and Efficacy of Immunomodulation With A Monoclonal Antibody Against… · University of Chicago · Phase 1/2
2026-07-30
Enrollment closed, study ongoing
Primary completion moved earlier: 2027-06 → 2026-03-15
Completion pushed: 2027-12 → 2027-12-31
NCT03878459 Dapagliflozin Plus Pioglitazone in T1DM · The University of Texas Health Science Center at San Antonio · Phase 4
2026-08-15
Recruitment opened
NCT07560813 NOURISH - A Healthcare-community Partnership to Improve Nutrition for Optimal Glycemic… · Ohio State University

New sponsor entrants, last 90 days sponsors with their first trial in this area

First postedTrialSponsorPhase
2026-08-26 NCT07787754 The Effect of Sea Buckthorn Extract in Patients With Type 1 Diabetes The First Affiliated Hospital of Guangzhou Medical University new
2026-08-25 NCT07785037 Omnipod 5 Implementation in Belgian Paediatric Diabetes Care Queen Fabiola Children's University Hospital new
2026-08-25 NCT07786064 Comparative Study of the Postprandial Glycemic Profile After Consumption of a High-fat… Konstantinos Makrilakis, MD new
2026-08-21 NCT07778147 Effects of Bedtime Snack Composition on Overnight Glucose in Children and Adolescents… Didem Güneş Kaya new
2026-08-17 NCT07769138 Implementation of Networked Continuous Glucose Monitoring With Telemetry Within the… Imperial College Healthcare NHS Trust new
2026-08-04 NCT07745244 Evaluation of the Accuracy and Safety of a Continuous Glucose Monitoring System SiBionics, Co, Ltd new
2026-08-03 NCT07742306 Continuous Glucose Monitoring in High-Risk Children and Youth With Type 1 Diabetes in the… Life for a Child Program, Diabetes Australia new
2026-07-31 NCT07739342 Evaluating the Occurrence of DKA in People With Type I Diabetes Abbott Diabetes Care new
2026-07-27 NCT07728435 Cardiopulmonary Fitness and Health-Related Quality of Life in Children and Adolescents… Institut Saint Pierre new
2026-07-24 NCT07726680 GlycoQuest: An AI-Adaptive CGM-Integrated Serious Game for Pediatric Type 1 Diabetes Shifa International Hospital new

Active trials by phase

Early Phase 1
13
Phase 1
16
Phase 1/2
11
Phase 2
42
Phase 2/3
7
Phase 3
15
Phase 4
12
Not charted: 333 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 449

NCT IDTitleSponsorStatusUpdated
Phase 4
NCT07427251 The Postprandial Hypo-Avoid Study Steno Diabetes Center Copenhagen Recruiting 2026-08-13
NCT07086443 Randomized Evaluation of Nonhealing Diabetic Foot Ulcers With Exclusive Wound Therapy Sequence LifeScience, Inc. Recruiting 2026-05-19
NCT07293715 Permissive Versus Strict Intrapartum Glucose Management in Type 1 Diabetes (PRISM-T1D) Ohio State University Recruiting 2026-04-29
NCT07159282 A Multicenter, Prospective, Controlled Clinical Trial Evaluating the Efficacy of a Single… Applied Biologics, LLC Recruiting 2026-02-11
NCT05641753 Cholesterol Lowering and Residual Risk in Diabetes, Type 1 NYU Langone Health Recruiting 2025-12-29
NCT06021145 Effectiveness of Empagliflozin Added to Automated Insulin Delivery (AID) Systems in… McGill University Health Centre/Research Institute of the McGill University Health Centre Recruiting 2024-08-09
NCT03463564 Insulin Pump vs Multiple Daily Injections of Insulin and Glyco-metabolic Control in Type… University of Campania Luigi Vanvitelli Recruiting 2018-03-15
NCT03878459 Dapagliflozin Plus Pioglitazone in T1DM The University of Texas Health Science Center at San Antonio Active, Not Recruiting 2026-07-29
NCT06922656 Can the Addition of Pioglitazone to SGLT2 Inhibitor in Type 1 Diabetic Patients Amplify… Dasman Diabetes Institute Not Yet Recruiting 2025-08-29
NCT06600776 Mealtime or Post-meal Dosing of URLi in Medtronic 780G Hybrid Closed Loop System Tel-Aviv Sourasky Medical Center Not Yet Recruiting 2024-09-24
NCT06532682 Efficacy of Dapagliflozin in Early Diabetic Nephropathy in Type 1 Diabetes The First Affiliated Hospital with Nanjing Medical University Active, Not Recruiting 2024-08-01
NCT04698330 Effects Of Berberine Plus Inulin On Diabetes Care in Patients With LADA Second Xiangya Hospital of Central South University Not Yet Recruiting 2022-02-25
Phase 3
NCT07088068 A Study to Investigate Efficacy and Safety of Teplizumab Compared With Placebo in… Sanofi Recruiting 2026-08-10
NCT06217302 Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and… Alessandro Doria Recruiting 2026-03-24
NCT06832410 An Efficacy, Safety, and Tolerability Study of VX-880 in Participants With Type 1… Vertex Pharmaceuticals Incorporated Recruiting 2026-03-23
NCT07258394 Clinical Study for Dimethyl Fumarate in Preserving Islet β-Cell Function in Type 1… Nanjing Medical University Recruiting 2026-03-05
NCT06630585 GIP/GLP-1RA as Adjunctive to Automated Insulin Delivery in Adults With Type 1 Diabetes University of Bern Recruiting 2026-01-26
NCT06894784 A Clinical Trial to Evaluate The Effects of Semaglutide and Empagliflozin Combined to… McGill University Health Centre/Research Institute of the McGill University Health Centre Recruiting 2025-03-30
NCT06082063 Multifactorial Intervention to Reduce Cardiovascular Disease in Type 1 Diabetes Steno Diabetes Center Copenhagen Recruiting 2025-01-10
NCT07670650 PRISE (Personalized Response and Immunologic Surveillance of Endogenous C-Peptide… University of Florida Not Yet Recruiting 2026-06-26
NCT06914895 A Study of Tirzepatide (LY3298176) Compared With Placebo in Adults With Type 1 Diabetes… Eli Lilly and Company Active, Not Recruiting 2026-05-12
NCT00679042 Islet Transplantation in Type 1 Diabetic Patients Using the University of Illinois at… CellTrans Inc. Active, Not Recruiting 2026-04-06
NCT06962280 A Long-Term Study of Tirzepatide (LY3298176) in Adults With Type 1 Diabetes and Obesity… Eli Lilly and Company Active, Not Recruiting 2026-02-17
NCT01320345 The Fenofibrate And Microvascular Events in Type 1 Diabetes Eye. University of Sydney Active, Not Recruiting 2026-01-20
NCT04583462 Impact of Metformin on Peripheral Arterial Calcification in Type 1 Diabetes Assistance Publique - Hôpitaux de Paris Active, Not Recruiting 2025-11-24
See all 449 active Type 1 Diabetes trials with filters →

Top sponsors by active trials in this area

University of Colorado, Denver (10) · Sanofi (9) · Second Xiangya Hospital of Central South University (7) · Steno Diabetes Center Copenhagen (7) · Institut de Recherches Cliniques de Montreal (6) · University of Aarhus (6) · University of California, San Diego (6) · Vanderbilt University Medical Center (6) · City of Hope Medical Center (5) · Insulet Corporation (5)

Get alerts when Type 1 Diabetes trials change
Status changes, date slips, and new sponsor entrants: detected daily, delivered to your inbox.
Start monitoring free