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NCT07787754 · ClinicalTrials.gov record · last posted 2026-08-26

The Effect of Sea Buckthorn Extract in Patients With Type 1 Diabetes

Study acronym: SBTT1D
StatusCompleted
PhaseNot applicable
Started2020-01-01
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from the ClinicalTrials.gov record
Type 1 diabetes (T1D) is an autoimmune disease characterized by the destruction of insulin-producing β-cells by autoreactive T cells. Sea buckthorn (SBT), a traditional Chinese medicine homologous to food, confers beneficial effects on the autoimmune system. Whether SBT regulates the glucose metabolism and immune microenvironment in T1D remains unknown. This study aims to investigate the impact of SBT on glycemic control and T-cell balance in patients with T1D. Patients with T1D consumed 10g of SBT extracts daily for 12 weeks. Clinical and experimental data were analyzed at the baseline and after 12 weeks of SBT treatment. Healthy controls were enrolled with no treatment. Side adverse effects will be recorded in this study.
Trial Details
NCT Number NCT07787754
Lead Sponsor The First Affiliated Hospital of Guangzhou Medical University
Conditions Type 1 Diabetes
Enrollment 30 participants
Start Date 2020-01-01
Primary Completion 2023-12-31 (estimated)
Study Completion 2023-12-31 (estimated)
Updated on ClinicalTrials.gov 2026-08-26