Disease landscape

Diabetes clinical trials

Get alerts when Diabetes trials change

3,008 active trials 1,551 recruiting 151 Phase 3 1,376 sponsors 411 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-08-28

What changed in the last 30 days showing 61 of 411 changes on 20 trials

2026-08-27
Trial terminated
Trial terminated: Stopped for futility.
Primary completion moved earlier: 2027-12 → 2026-06-24
Completion moved earlier: 2027-12 → 2026-06-24
NCT05018585 A Phase III Study to Investigate if the Study Drug Diamyd Can Preserve Insulin Production… · Diamyd Medical AB · Phase 3
2026-08-28
Trial terminated
Trial terminated: Funding was terminated for the study.
Enrollment reduced: 353 → 37 participants
Primary completion moved earlier: 2028-03-31 → 2026-05-19
Completion moved earlier: 2028-05-31 → 2026-06-19
NCT05884775 Novel Digital Patient-Reported Outcomes Tool for Diabetes Management · NYU Langone Health
2026-08-27
Withdrawn before enrolling
Trial withdrawn: No funding
Enrollment reduced: 100 → 0 participants
NCT06445270 Lifestyle Interventions to Improve Glycemic Parameters and Reduce Gestational Diabetes in… · Indiana University
2026-08-21
Withdrawn before enrolling
Trial withdrawn: Lack of resources
Enrollment reduced: 1000 → 0 participants
NCT06596330 Integration of a Trained Language Model to Improve Glycemic Control With the My Heart… · Stanford University
2026-08-06
Withdrawn before enrolling
Trial withdrawn: Changed IRB number
Enrollment reduced: 70 → 0 participants
Primary completion moved earlier: 2028-08 → 2026-07-31
Completion moved earlier: 2028-08 → 2026-07-31
NCT05985135 Impact of Insulin Deprivation and Hyperglycemia on Plasma Protein Synthesis in People… · Mayo Clinic
2026-07-31
Trial terminated
Trial terminated: Recruitment.
Primary completion pushed: 2025-12 → 2026-07-20
Enrollment reduced: 100 → 33 participants
Completion pushed: 2025-12 → 2026-07-20
NCT06786130 Societal Burden Associated With Type 1 Diabetes in Canada · PeriPharm
2026-08-21
Primary completion pushed: 2026-12-23 → 2027-04-16
Trial sites expanded: 45 → 48 locations
Completion pushed: 2027-01-07 → 2027-04-30
NCT07340320 A Study of CX11 Tablets in Patients With Type 2 Diabetes Mellitus · Corxel Pharmaceuticals · Phase 2
2026-08-22
Primary completion pushed: 2026-02 → 2026-09
Enrollment closed, study ongoing
Completion pushed: 2026-06 → 2027-01
NCT05822544 Phase 1/1b Study of TLC-6740 in Healthy Subjects and Subjects With Obesity, With or… · OrsoBio, Inc · Phase 1
2026-08-28
Primary completion pushed: 2029-03-31 → 2029-06-30
Trial status changed: Recruiting → Not Yet Recruiting
Completion moved earlier: 2030-04-30 → 2029-12-31
NCT07495956 cfMSC Therapy for Diabetes · Shenzhen Geno-Immune Medical Institute · Phase 1/2
2026-08-28
Primary completion pushed: 2028-05 → 2029-02
Completion pushed: 2028-08 → 2030-02
NCT07325201 Mitigating DKA in Type 1 Diabetes for Safe Use of SGLT Inhibitors Using Dual Continuous… · HealthPartners Institute · Phase 2
2026-08-12
Primary completion pushed: 2026-08-04 → 2028-03-23
Completion moved earlier: 2028-08-31 → 2028-03-23
NCT07112339 A Research Study to See How Well Weekly Insulin Icodec Maintains Blood Sugar Levels… · Novo Nordisk A/S · Phase 4
2026-08-27
Primary completion pushed: 2025-12-01 → 2027-02-01
Trial status changed: Recruiting → Not Yet Recruiting
Completion pushed: 2026-05-01 → 2027-02-01
NCT07114822 HOPE Intervention for Fitness · University of California, Irvine
2026-08-07
Primary completion pushed: 2025-09-30 → 2026-03-14
Trial status changed: Not Yet Recruiting → Active, Not Recruiting
Trial sites expanded: 0 → 6 locations
Completion pushed: 2026-03-31 → 2026-12-24
NCT06587438 Effect of CGM on Glucose Control in Non-insulin-treated Patients With Type 2 Diabetes… · Sinocare
2026-08-06
Primary completion pushed: 2026-07-01 → 2027-02-01
Enrollment closed, study ongoing
Enrollment increased: 264 → 350 participants
Completion pushed: 2026-10-01 → 2027-10-01
NCT06267391 Safety and Effectiveness of Endoscopic Intestinal Re-Cellularization Therapy in… · Endogenex, Inc.
2026-08-05
Primary completion pushed: 2026-06 → 2026-12
Completion pushed: 2026-06 → 2026-12
NCT07187479 Outcomes of Physiologic Insulin Resensitization (PIR) in Patients With Chronic Kidney… · Well Cell Global
2026-08-26
Primary completion pushed: 2025-10 → 2028-12
Completion pushed: 2026-10 → 2029-12
NCT04326192 Brown Adipose Tissue Activation by Spinal Cord Stimulation · Oregon Health and Science University
2026-08-25
Primary completion pushed: 2026-01-15 → 2026-05-15
Trial completed
Completion pushed: 2026-04-15 → 2026-08-19
NCT07256613 Non-surgical Periodontal Therapy and Kidney Outcomes in Type 2 Diabetes Mellitus · Dow University of Health Sciences
2026-08-22
Primary completion pushed: 2026-06-01 → 2027-06-01
Trial status changed: Enrolling by Invitation → Recruiting
NCT07310849 Digital Care for Holistic Health in Older Adults With Diabetes and Multimorbidity · Chang Gung University of Science and Technology
2026-08-22
Primary completion pushed: 2026-06 → 2027-06
Enrollment closed, study ongoing
NCT04696159 Impact of Per Oral Pyloromyotomy (POP) on Glycemic Control in Diabetes · Matthew Allemang
2026-08-25
Primary endpoint(s) modified
NCT07187531 SAFety and Efficacy of Human Anti-thymocyte ImmunoGlobUlin SAB-142 ARresting Progression… · SAb Biotherapeutics, Inc. · Phase 2

New sponsor entrants, last 90 days sponsors with their first trial in this area

First postedTrialSponsorPhase
2026-08-26 NCT07787754 The Effect of Sea Buckthorn Extract in Patients With Type 1 Diabetes The First Affiliated Hospital of Guangzhou Medical University new
2026-08-26 NCT07788235 Diabetes and Permanent Disabilities Assuta Medical Center new
2026-08-25 NCT07785037 Omnipod 5 Implementation in Belgian Paediatric Diabetes Care Queen Fabiola Children's University Hospital new
2026-08-25 NCT07786064 Comparative Study of the Postprandial Glycemic Profile After Consumption of a High-fat… Konstantinos Makrilakis, MD new
2026-08-24 NCT07783451 Effectiveness of Combining Patient Follow-Up With an Educational Intervention on… Aysenur Aktemur new
2026-08-21 NCT07779928 An Innovative Proprioceptive Instrument for Upper Extremities National Cheng-Kung University Hospital new
2026-08-21 NCT07779343 OBESIAL: A Prospective Interventional Real-world Study of a Multidisciplinary Obesity… University of Health Sciences, Algeria new
2026-08-21 NCT07778147 Effects of Bedtime Snack Composition on Overnight Glucose in Children and Adolescents… Didem Güneş Kaya new
2026-08-21 NCT07779044 Mindfulness-Based Cognitive Behavioral Program for People With Diabetes Mellitus Center for Strategic Studies and Health Training, Syria new
2026-08-20 NCT07776314 Are There Any Clinical Benefits to Screening for Late -Onset Gestational Diabetes… Izmir Ataturk Training and Research Hospital new

Active trials by phase

Early Phase 1
42
Phase 1
91
Phase 1/2
37
Phase 2
169
Phase 2/3
20
Phase 3
131
Phase 4
155
Not charted: 2,363 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 3,008

NCT IDTitleSponsorStatusUpdated
Phase 4
NCT07771010 The Effect of Empagliflozin and Metformin on Oxidative Capacity and Microvascular… University Medical Centre Ljubljana Recruiting 2026-08-18
NCT05305287 Quantifying Hepatic Mitochondrial Fluxes in Humans The University of Texas Health Science Center at San Antonio Recruiting 2026-08-17
NCT07427251 The Postprandial Hypo-Avoid Study Steno Diabetes Center Copenhagen Recruiting 2026-08-13
NCT03883412 Effect of Exercise and/or Liraglutide on Vascular Dysfunction and Insulin Sensitivity in… University of Virginia Recruiting 2026-08-12
NCT07112339 A Research Study to See How Well Weekly Insulin Icodec Maintains Blood Sugar Levels… Novo Nordisk A/S Recruiting 2026-08-11
NCT07228195 SGLT2i Therapy in Islet Transplantation (SIT) University of Minnesota Recruiting 2026-07-22
NCT07719894 Cilostazol and Aspirin for Cardiovascular Event Prevention in Patients With Type 2… Seoul National University Bundang Hospital Recruiting 2026-07-22
NCT07711171 Efficacy and Safety of Canagliflozin in the Treatment of Type 2 Diabetes With Mild… Fudan University Recruiting 2026-07-17
NCT06003153 GLUCOSE-MGH: Genetic Links Understood Through Challenge With Oral Semaglutide Exposure at… Massachusetts General Hospital Recruiting 2026-07-08
NCT07307235 Efficacy and Safety of iGlarLixi Versus Standard of Care in a Real-world Adult China… Shanghai Zhongshan Hospital Recruiting 2026-07-07
NCT07017270 Glucagon-like-peptide-1 Receptor Agonists in Patients Receiving Maintenance Dialysis Unity Health Toronto Recruiting 2026-06-26
NCT06445946 DECIDE: A Comparative Effectiveness Trial of Metformin Versus Insulin for the Treatment… Ohio State University Recruiting 2026-06-25
NCT06699810 Modeling Ketosis-Prone Diabetes Remission Via Diverse Mechanisms of Glucotoxicity Emory University Recruiting 2026-06-15
NCT06291155 Mechanism of SGLT2 Inhibition in the Kidney University of Michigan Recruiting 2026-06-11
NCT07614230 SGLT2 Inhibitors on Coronary Atherosclerosis Progression Via Perivascular Adipose Tissue… Junjie Yang Recruiting 2026-05-29
NCT06478186 Knee Osteoarthritis Treatment With Zilretta vs. Kenalog in the Context of Type II Diabetes University of Kansas Medical Center Recruiting 2026-05-28
NCT07086443 Randomized Evaluation of Nonhealing Diabetic Foot Ulcers With Exclusive Wound Therapy Sequence LifeScience, Inc. Recruiting 2026-05-19
NCT07588438 Efficacy, Safety, and Tolerability of Tirzepatide in Real-World Conditions in Paraguay. Las Rías Medical Center Recruiting 2026-05-19
NCT07224893 Once-Daily vs Twice-Daily Insulin Glargine in Pregestational Diabetes Management Eastern Virginia Medical School Recruiting 2026-05-15
NCT07561541 Extended Oral Antibiotic Prophylaxis in Diabetic Fracture Patients Texas Tech University Health Sciences Center, El Paso Recruiting 2026-05-08
NCT05365425 Choline Fenofibrate and Carotid Atherosclerosis in Patients With Type 2 Diabetes and… Seoul National University Bundang Hospital Recruiting 2026-05-05
NCT05365438 Atmeg (Atorvastatin and Omega-3 Combination) and Carotid Atherosclerosis in Patients With… Seoul National University Bundang Hospital Recruiting 2026-05-05
NCT06399835 Enavogliflozin vs. Pioglitazone on Glucose and Atherosclerosis Seoul National University Bundang Hospital Recruiting 2026-05-05
NCT06402747 Clopidogrel Versus Cilostazol on Vessels Seoul National University Bundang Hospital Recruiting 2026-05-05
NCT06613854 Effect of Early Combination Antihyperglycemic Treatment on Metabolic Control in… University Medical Centre Ljubljana Recruiting 2026-04-30
See all 3,008 active Diabetes trials with filters →

Top sponsors by active trials in this area

Novo Nordisk A/S (28) · Assiut University (24) · Eli Lilly and Company (23) · University of Colorado, Denver (22) · University of Alabama at Birmingham (21) · Steno Diabetes Center Copenhagen (19) · Johns Hopkins University (18) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (18) · Medical College of Wisconsin (16) · National Taiwan University Hospital (16)

Get alerts when Diabetes trials change
Status changes, date slips, and new sponsor entrants: detected daily, delivered to your inbox.
Start monitoring free