Tirzepatide vs Semaglutide in Individuals at Cardiovascular Risk But Without Diabetes.

Investigators are building an empirical evidence base for real world data through large-scale emulation of randomized controlled trials. The investigators' goal is to understand for what types of clinical questions real world data analyses can be conducted with confidence and how to implement such studies.

NCT Number	NCT07619508
Lead Sponsor	Brigham and Women's Hospital
Conditions	Obesity, Overweight
Enrollment	100,000 participants
Start Date	2026-02-10
Primary Completion	2026-06-01 (estimated)
Study Completion	2026-06-01 (estimated)
Updated on ClinicalTrials.gov	2026-07-09