Disease landscape

Chronic Kidney Disease clinical trials

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1,117 active trials 572 recruiting 74 Phase 3 623 sponsors 116 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-08-28

What changed in the last 30 days showing 49 of 116 changes on 19 trials

2026-08-22
Primary completion pushed: 2026-12 → 2027-12
Completion pushed: 2027-03 → 2028-03
NCT07006831 A Multicenter, Prospective Blood Collection Study in a Kidney Transplant Population · Devyser Inc.
2026-08-28
Primary completion pushed: 2028-05 → 2029-02
Completion pushed: 2028-08 → 2030-02
NCT07325201 Mitigating DKA in Type 1 Diabetes for Safe Use of SGLT Inhibitors Using Dual Continuous… · HealthPartners Institute · Phase 2
2026-08-18
Primary completion pushed: 2026-03 → 2026-07-24
Enrollment reduced: 244 → 210 participants
Trial completed
Trial sites reduced: 21 → 18 locations
Completion pushed: 2026-03 → 2026-07-24
NCT05489120 Low-Protein Diet With Low-Protein Foods Versus a LPD Without LP Foods in Patients With… · Dr. Schär AG / SPA
2026-07-31
Primary completion pushed: 2027-04-23 → 2027-07-23
Completion pushed: 2027-04-23 → 2027-07-23
NCT06734234 A Study to Evaluate the Safety, Tolerability, and Effects on Blood and Urine Markers of… · GlaxoSmithKline · Phase 1
2026-08-27
Primary completion pushed: 2025-12-30 → 2026-06-30
Primary endpoint(s) modified
Enrollment reduced: 60 → 20 participants
Trial completed
Completion moved earlier: 2026-12-30 → 2026-07-30
NCT04212923 eHealth Based Self-management Intervention for Chronic Kidney Disease Care in China · Leiden University Medical Center
2026-08-14
Primary completion pushed: 2024-12-02 → 2026-12-01
NCT04802395 Real World Evidence Clinical Utility Study of KidneyIntelX · Renalytix AI, Inc.
2026-08-05
Primary completion pushed: 2026-06 → 2026-12
Completion pushed: 2026-06 → 2026-12
NCT07187479 Outcomes of Physiologic Insulin Resensitization (PIR) in Patients With Chronic Kidney… · Well Cell Global
2026-07-30
Primary completion pushed: 2025-12 → 2027-07
Completion pushed: 2026-12 → 2028-12
NCT06329310 Xeltis Hemodialysis Access (aXess) Conduit: aXess-E Study · Xeltis
2026-08-20
Primary completion pushed: 2026-06-01 → 2026-09-01
Completion pushed: 2026-07-01 → 2026-11-01
NCT06430684 Feasibility Trial of Sodium-GLucose coTransporter 2 INhibitors in Pediatric Chronic… · Ann & Robert H Lurie Children's Hospital of Chicago · Early Phase 1
2026-08-22
Primary completion pushed: 2026-06-01 → 2027-06-01
Trial status changed: Enrolling by Invitation → Recruiting
NCT07310849 Digital Care for Holistic Health in Older Adults With Diabetes and Multimorbidity · Chang Gung University of Science and Technology
2026-08-12
Primary completion pushed: 2026-06 → 2026-10-30
NCT05705414 Oral Intradialytic Amino Acid Supplementation to Vitalize End-stage Kidney Disease… · The University of Texas Health Science Center at San Antonio · Early Phase 1
2026-08-13
Primary completion pushed: 2025-02-28 → 2025-12-01
Enrollment reduced: 720 → 556 participants
Trial completed
Completion pushed: 2025-12-01 → 2025-12-31
NCT06833541 Research on Gut Microbiota and Metabolomics in Diabetic Kidney Disease · The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine
2026-08-06
Primary completion pushed: 2026-08 → 2028-08
Completion pushed: 2026-08 → 2028-08
NCT06439862 Study of the Quality of Life in School Aged-children With Posterior Urethral Valves · Hospices Civils de Lyon
2026-08-14
Primary endpoint(s) modified
Trial sites expanded: 1 → 59 locations
NCT07481526 A Prospecitve Multicenter, Observational Registry Study · AstraZeneca
2026-08-25
Primary endpoint(s) modified
Enrollment reduced: 100 → 57 participants
Trial status changed: Enrolling by Invitation → Completed
Primary completion moved earlier: 2027-09 → 2024-06-19
Completion moved earlier: 2029-05 → 2024-06-19
NCT05530356 Renal Hemodynamics, Energetics and Insulin Resistance: A Follow-up Study · University of Colorado, Denver
2026-08-20
Primary endpoint(s) modified
NCT07325201 Mitigating DKA in Type 1 Diabetes for Safe Use of SGLT Inhibitors Using Dual Continuous… · HealthPartners Institute · Phase 2
2026-08-18
Primary endpoint(s) modified
NCT07729358 Evaluation of the Effect of Light Therapy on the Evolution of Self-reported Depressive… · Centre Hospitalier Annecy Genevois
2026-08-11
Enrollment reduced: 280 → 220 participants
NCT04634916 Post-market Surveillance Study of the BD® WavelinQ™ EndoAVF System · C. R. Bard
2026-08-14
Enrollment reduced: 200 → 96 participants
Phase changed: Phase 1 → Phase 2
Trial completed
Primary completion moved earlier: 2026-05-31 → 2026-04-04
Completion moved earlier: 2026-05-31 → 2026-04-04
NCT06203977 Inflammation REduction to Prevent cArdiovascular Injury in Renal Disease (REPAIR) · Hamilton Health Sciences Corporation · Phase 2
2026-07-31
Enrollment reduced: 60 → 18 participants
Enrollment closed, study ongoing
NCT05719714 Effect of Dapagliflozin on Metabolomics and Cardiac Mechanics in Chronic Kidney Disease · Northwestern University · Phase 1/2

New sponsor entrants, last 90 days sponsors with their first trial in this area

First postedTrialSponsorPhase
2026-08-26 NCT07788014 A Phase 1 Study of Single and Multiple Ascending Doses of GV-100 Gilva Therapeutics Inc. new Phase 1
2026-08-25 NCT07786025 DisTal Arterio-Venous Fistula Feasibility Distal Inc. new
2026-08-25 NCT07784452 Comparing Hepatitis B Vaccination Schedules in Patients on Hemodialysis Jinnah Hospital new
2026-08-25 NCT07786168 Roxadustat Versus Erythropoietin for Anaemia Treatment in Diabetic Nephropathy Hanzla Arshad new
2026-08-20 NCT07775482 Finerenone for AKI: a Multicenter, Randomized, Placebo-Controlled Feasibility Pilot Trial Jean-Maxime Côté new
2026-08-20 NCT07776925 Effects of Maqui Supplementation on Gut Microbiota, Inflammation, and Oxidative Stress in… Universidad Mayor new
2026-08-20 NCT07777523 Non-invasive Testing for End-Stage Chronic Kidney Disease Gisens Biotech new
2026-08-20 NCT07775846 QUARTET-DKD: Quadruple Therapy for Type 2 Diabetic Nephropathy Huijie Zhang new Phase 4
2026-08-19 NCT07772856 Liberalizing Potassium Restrictions in Patients Receiving Hemodialysis University of Ontario Institute of Technology new
2026-08-17 NCT07769073 Efficacy of Nalfurafine for Chronic Kidney Disease-Associated Pruritus in Twice-Weekly… Indonesia University new Phase 4

Active trials by phase

Early Phase 1
9
Phase 1
45
Phase 1/2
26
Phase 2
84
Phase 2/3
7
Phase 3
67
Phase 4
83
Not charted: 796 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 1,117

NCT IDTitleSponsorStatusUpdated
Phase 4
NCT07380113 Anrikefon vs Nalfurafine for Sleep Quality in Hemodialysis Patients With CKD-aP Zhujiang Hospital Recruiting 2026-08-25
NCT06110130 Effect of Empagliflozin on Podocyte Specific Proteins in African American Veterans With… Washington D.C. Veterans Affairs Medical Center Recruiting 2026-08-21
NCT07741292 Niaoduqing Granules in Older Adults With Impaired Kidney Function Huashan Hospital Recruiting 2026-08-03
NCT06396416 Obesity Management for Kidney TRANSPLANTation: OK-TRANSPLANT 2 Western University, Canada Recruiting 2026-06-29
NCT07017270 Glucagon-like-peptide-1 Receptor Agonists in Patients Receiving Maintenance Dialysis Unity Health Toronto Recruiting 2026-06-26
NCT06291155 Mechanism of SGLT2 Inhibition in the Kidney University of Michigan Recruiting 2026-06-11
NCT06291077 Comparison of the Effects of Belatacept and Anticalcineurins on Endothelial Function in… University Hospital, Rouen Recruiting 2026-06-09
NCT06860711 Safety of Short-course of NSAIDs in Pediatric Patients With CKD University of Colorado, Denver Recruiting 2026-06-08
NCT05671991 Effect of Empagliflozin on Peritoneal and Kidney Function in End Stage Renal Disease Yale University Recruiting 2026-05-22
NCT03862859 The Danish Warfarin-Dialysis Study - Safety and Efficacy of Warfarin in Patients With… Nicholas Carlson Recruiting 2026-05-19
NCT06560801 Dapagliflozin on Renal Morphology and Renal Perfusion in Patients One Year After Kidney… University of Erlangen-Nürnberg Medical School Recruiting 2026-05-06
NCT07405216 Efficacy and Safety of Sodium-Glucose Cotransporter-2 Inhibitors in Adolescents With… Centenario Hospital Miguel Hidalgo Recruiting 2026-04-27
NCT06013865 Empagliflozin Treatment in Kidney Transplant Recipients VA Office of Research and Development Recruiting 2026-04-21
NCT06625073 Randomized Trial of SGLT2i in Heart Transplant Recipients VA Office of Research and Development Recruiting 2026-01-22
NCT06256991 Potassium Correction for RAAS Optimization in Chronic Kidney Disease University Medical Center Groningen Recruiting 2025-12-19
NCT07259512 Single and Twice-daily Dosing of Ramipril on Renal Function in Chronic Kidney Disease… Evi Liliek Wulandari Recruiting 2025-12-10
NCT07271420 Blood Pressure Control With Thiazide Diuretics in Peritoneal Dialysis Patients Chinese University of Hong Kong Recruiting 2025-12-09
NCT07239570 A Biomarker-targeted Clinical Trial to Optimize Treatment for Patients With Chronic… Peter Rossing Recruiting 2025-11-20
NCT04381143 ASPIrin in Reducing Events in Dialysis ( ASPIRED ) Guangdong Provincial People's Hospital Recruiting 2025-11-18
NCT07187713 ACE Reno, Pico Cell Matrix and Its Effect on eGFR in Chronic Kidney Diseases Ace Cells Lab Limited Recruiting 2025-09-23
NCT07182422 AST-120 (Kremezin®) for the Renal Protection and Attenuation of Decline in Acute Kidney… Chang Gung Memorial Hospital Recruiting 2025-09-19
NCT07182942 The Effect and Mechanism of Xiqing Regulating Intestinal Homeostasis on Drug Efficacy of… Chujin Cao Recruiting 2025-09-19
NCT07030894 Nefecon and Ambrisentan in IgA Nephropathy The First Hospital of Jilin University Recruiting 2025-09-15
NCT07045155 Pegmolesatide Treatment for Anemia in Patients Undergoing Long-term Dialysis Chinese PLA General Hospital Recruiting 2025-09-12
NCT06701825 Effectiveness and Cost-effectiveness of a Pre-emptive Genotyping Strategy in Patients… Instituto de Investigación Hospital Universitario La Paz Recruiting 2025-09-11
See all 1,117 active Chronic Kidney Disease trials with filters →

Top sponsors by active trials in this area

Assiut University (22) · AstraZeneca (16) · VA Office of Research and Development (14) · Mayo Clinic (13) · Mario Negri Institute for Pharmacological Research (11) · Sohag University (11) · University of Colorado, Denver (11) · National Taiwan University Hospital (10) · Bayer (9) · Brigham and Women's Hospital (9)

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