Sponsor Pipeline

Massachusetts General Hospital Clinical Trial Pipeline

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
329
Active Trials
167
Recruiting
7
Phase 3
10
Disease Areas
41
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-06-12 NCT03873610
Resiliency Training in Adolescents With NF1 and NF2
Trial completed
2026-06-12 NCT05962879
Development of a Transdiagnostic Intervention for Adolescents at Risk for Serious Mental…
date change Completion moved earlier: 2027-07-31 -> 2027-05-31
2026-06-09 NCT07227753
The Association Between Gut Microbiota Diversity and Postpartum Depression
Trial completed
2026-06-05 NCT06674109
SAVE-Care (Sodium Glucose Cotransporter-2 Inhibitors [SGLT2i] As Novel Gout Care) Trial
Recruitment opened
2026-06-04 NCT04496947
Pilot Study Evaluating the Impact of Stress Reduction on Atherosclerotic : Heart and Mind…
date change Primary completion pushed: 2026-01-31 -> 2027-01-01
2026-06-04 NCT04496947
Pilot Study Evaluating the Impact of Stress Reduction on Atherosclerotic : Heart and Mind…
date change Completion pushed: 2026-12-30 -> 2027-12-31
2026-06-04 NCT04430894
KRDI in Transplant-Eligible MM
date change Completion pushed: 2026-03-30 -> 2026-12-30
2026-06-03 NCT06878859
Preliminary Efficacy Trial of a Digital Intervention for Depression and Cannabis Use
date change Primary completion pushed: 2028-01 -> 2028-01-31
2026-06-03 NCT06878859
Preliminary Efficacy Trial of a Digital Intervention for Depression and Cannabis Use
date change Completion pushed: 2029-01 -> 2029-06-29
2026-05-30 NCT05881304
Switching Individuals in Treatment for Opioid Use Disorder Who Smoke Cigarettes to the…
date change Primary completion pushed: 2025-11-30 -> 2025-12-31
2026-05-29 NCT04824066
The Role of Wearable Devices in Predicting and Detecting Complications and Adverse Events
Primary endpoint(s) modified
2026-05-29 NCT04824066
The Role of Wearable Devices in Predicting and Detecting Complications and Adverse Events
Enrollment increased: 1200 -> 2400 participants
2026-05-27 NCT07312227
A Prospective Longitudinal Observational Cohort Study of Pregnant Women Residing at High…
overall status: "Active Not Recruiting" → "Recruiting"
2026-05-27 NCT07312227
A Prospective Longitudinal Observational Cohort Study of Pregnant Women Residing at High…
Enrollment increased: 22 -> 27 participants
2026-05-27 NCT06872346
Personalized Risk-based Follow-up of Cervical Cancer Screening in Practice, RCT
date change Primary completion pushed: 2028-04-15 -> 2028-06-15
2026-05-27 NCT07597239
Thromboelastography With Platelet Mapping to Guide Antiplatelet Therapy After Lower…
date change Primary completion pushed: 2024-10-30 -> 2026-02-17
2026-05-27 NCT06152627
Voice Therapy Per the Rehabilitation Treatment Specification System
Phase changed: [] -> ['NA']
2026-05-23 NCT05662423
Preventing Childbirth-Related PTSD With Expressive Writing
date change Primary completion pushed: 2026-05-31 -> 2026-07-20
2026-05-23 NCT05662423
Preventing Childbirth-Related PTSD With Expressive Writing
date change Completion pushed: 2026-05-31 -> 2026-07-31
2026-05-23 NCT07269808
Sedation During Endoscopy Using Remimazolam: Efficacy in a Novel Exploration
overall status: "Recruiting" → "Active Not Recruiting"
Showing 20 of 41 changes detected in the last 30 days.
New Trial Filings, Last 30 Days
First PostedTrialPhaseStatus
2026-06-11 NCT07641205 Cognitive-behavioral Therapy vs. Nutrition Counseling for Avoidant/Restrictive Food… Not Yet Recruiting
2026-06-10 NCT07639827 A Pilot Randomized Controlled Trial of a Mental Fitness Intervention for Anesthesiology… Not Yet Recruiting
2026-06-10 NCT07639840 An Open-label, Single Center Study Evaluating the Safety and Efficacy of Roflumilast Foam… Phase 2 Not Yet Recruiting
2026-05-29 NCT07613840 Personalizing Thromboprophylaxis for Patients With Peripheral Artery Disease Recruiting
2026-05-29 NCT07614893 Clinician Notification to Increase Aspirin Prophylaxis for Preeclampsia Prevention Not Yet Recruiting
2026-05-29 NCT07614906 Nitric Oxide Consumption as a Predictor of Vasospasm in Subarachnoid Hemorrhage Recruiting
2026-05-28 NCT07610928 Stress Management and Meditative Movements for Asian Americans With Depression and… Not Yet Recruiting
2026-05-22 NCT07600801 LEGACY: Lung Cancer Screening in Individuals With a Lung Cancer Family History-Protocol B Not Yet Recruiting
2026-05-22 NCT07604207 Multi-organ Imaging of Microvascular and Metabolic Function Early Phase 1 Not Yet Recruiting
2026-05-19 NCT07597239 Thromboelastography With Platelet Mapping to Guide Antiplatelet Therapy After Lower… Active, Not Recruiting
Active Trials by Phase
Phase 4
22
Phase 3
7
Phase 2
57
Phase 1/2
6
Phase 1
20
Early Phase 1
15
Not specified
202
Active Trials — top 25 of 329
NCT IDTitleConditionStatus
Phase 4
NCT07131592 Effect of Intravenous and Topical Tranexamic Acid on Drain Output in Breast Reduction… Drain Output After Breast Reduction Surgery Recruiting
NCT06584942 Evaluation of Suvorexant for Reduction of Brain Reactivity in Patients With Cannabis Use… Cue-reactivity Recruiting
NCT07346079 Purified Cortrophin® Gel Efficacy and Safety Study of 2 Dose Levels in Patients With… Gout Arthritis Recruiting
NCT04945707 Impact of Intravenous Iron Repletion On Mechanisms of Exercise InTolerance in HFpEF… Iron-deficiency Recruiting
NCT07199335 Long-acting Cabotegravir Injectable Pre-exposure Prophylaxis for People Who Inject Drugs HIV Recruiting
NCT06003153 GLUCOSE-MGH: Genetic Links Understood Through Challenge With Oral Semaglutide Exposure at… Genetic Predisposition Recruiting
NCT06558188 Combined Anabolic Therapy Osteoporosis, Postmenopausal Recruiting
NCT07166939 45th Multicenter Airway Research Collaboration Asthma Acute Recruiting
NCT04400266 Buspirone and Melatonin for Depression Following Traumatic Brain Injury Depression Recruiting
NCT05853627 Mismatch vs. Standard Intervention During Memory Reconsolidation Blockade With… Stress Disorders, Post-Traumatic Recruiting
NCT05850091 Polygenic Risk-based Detection of Subclinical Coronary Atherosclerosis and Intervention… Coronary Artery Disease Recruiting
NCT06201676 Low-Dose Short-Term Ketorolac to Reduce Chronic Opioid Use in Orthopaedic Polytrauma… Orthopaedic Trauma Recruiting
NCT06751992 Neurocognitive Function Changes With Extended-Release Tacrolimus Among Older Kidney… Kidney Transplant Recipients Recruiting
NCT06674109 SAVE-Care (Sodium Glucose Cotransporter-2 Inhibitors [SGLT2i] As Novel Gout Care) Trial Gout and Hyperuricemia Recruiting
NCT06436274 Efficacy of Human Papillomavirus (HPV) Vaccination to Prevent Infection Among Women… Human Papilloma Virus Active, Not Recruiting
NCT07145866 Varenicline and Accelerated Transcranial Magnetic Stimulation (TMS) for Quitting Nicotine… Nicotine Dependence Not Yet Recruiting
NCT07439042 Buspirone for Anxiety in Autistic Youth Anxiety Not Yet Recruiting
NCT05003648 Treating Leg Symptoms in Women With X-linked Adrenoleukodystrophy Adrenoleukodystrophy Active, Not Recruiting
NCT07010302 Rituximab Versus Ravulizumab, Inebilizumab, Satralizumab, and Eculizumab in NMOSD NMOSD Not Yet Recruiting
NCT05010590 Anabolic Therapy in Postmenopausal Osteoporosis Postmenopausal Osteoporosis Active, Not Recruiting
NCT07535411 Bupivacaine Liposome Suspension Administration to Decreasre Peri-procedural Pain in… Analgesia Assessment Not Yet Recruiting
NCT07342452 Randomized Trial of Combination Treatment With Sofwave and Sculptra Skin Aging Not Yet Recruiting
Phase 3
NCT06192615 Minimizing ICU Neurological Dysfunction With Dexmedetomidine-induced Sleep (MINDDS II) Delirium Recruiting
NCT06810167 Assessing Tenapanor as a Treatment of CF-related Constipation. Cystic Fibrosis Recruiting
NCT06533865 Romosozumab as an Adjunct to Physiologic Estrogen Replacement in Functional Hypothalamic… FHA (Functional Hypothalamic Amenorrhea) Recruiting
View all 329 active Massachusetts General Hospital trials with filters →
Disease Areas
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