Clinical Trial

LEGACY: Lung Cancer Screening in Individuals With a Lung Cancer Family History-Protocol B

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Summary
This research is being done to determine if an image-based deep learning model (Sybil) can accurately predict the likelihood of future lung cancer based on chest computed tomography (CT) imaging from individuals with a family history of lung cancer.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2026-05-14.
Trial Details
NCT Number NCT07600801
Lead Sponsor Massachusetts General Hospital
Conditions Family History of Lung Cancer
Enrollment 2,250 participants
Start Date 2026-06-15
Primary Completion 2033-12-31 (estimated)
Study Completion 2035-12-31 (estimated)
Updated on ClinicalTrials.gov 2026-05-27