Clinical Trial

The Association Between Gut Microbiota Diversity and Postpartum Depression

Completed
View on ClinicalTrials.gov →
Summary
This study aims to examine whether naturally occurring bacteria in the gastrointestinal tract are associated with mood changes following childbirth, including postpartum depression. Biological samples will be collected before and after delivery to determine whether specific patterns in gut bacterial composition are linked to emotional states. The purpose of the research is to improve understanding of whether such microbial changes can help identify individuals at higher risk for postpartum depression, enabling earlier recognition and intervention.
Protocol Amendment History 1 change
critical Trial completed 2026-06-09
Trial Details
NCT Number NCT07227753
Lead Sponsor Massachusetts General Hospital
Collaborators: National Institute on Aging (NIA)
Conditions Depression During Pregnancy
Enrollment 30 participants
Start Date 2025-11-17
Primary Completion 2026-04-08 (estimated)
Study Completion 2026-04-08 (estimated)
Updated on ClinicalTrials.gov 2026-06-08