Notable
Oral Low Dose Naltrexone for Vulvodynia
Primary endpoint(s) modified
University of FloridaPhase 2 NCT07862400 Registry history of NCT07862400 on ClinicalTrials.gov (opens the registry)
24 trials changed in the last 30 days: 0 stopped, 10 with notable changes, 14 with minor changes only.
Primary endpoint(s) modified
University of FloridaPhase 2 NCT07862400 Registry history of NCT07862400 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Aug 30, 2026 to Aug 30, 2027
Also in this update: Study completion pushed from Feb 28, 2027 to Feb 28, 2028
University of FloridaPhase 4 NCT06588595 Registry history of NCT06588595 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Sep 16, 2026 to Mar 16, 2027
Also in this update: Study completion pushed from Dec 7, 2026 to May 7, 2027
University of FloridaNot applicable NCT05910619 Registry history of NCT05910619 on ClinicalTrials.gov (opens the registry)
Phase changed: not applicable → Phase 2
Also in this update: Interventions modified
University of FloridaPhase 2 NCT07766980 Registry history of NCT07766980 on ClinicalTrials.gov (opens the registry)
Recruitment opened
University of FloridaNot applicable NCT07789314 Registry history of NCT07789314 on ClinicalTrials.gov (opens the registry)
Recruitment opened
Also in this update: Interventions modified
University of FloridaPhase 1 NCT07569263 Registry history of NCT07569263 on ClinicalTrials.gov (opens the registry)
Recruitment opened
University of FloridaNot applicable NCT07782398 Registry history of NCT07782398 on ClinicalTrials.gov (opens the registry)
Recruitment opened
University of FloridaNot applicable NCT07636447 Registry history of NCT07636447 on ClinicalTrials.gov (opens the registry)
Recruitment opened
Also in this update: Start date pushed from Sep 1, 2026 to Sep 15, 2026
University of FloridaNot applicable NCT07799805 Registry history of NCT07799805 on ClinicalTrials.gov (opens the registry)
Results posted: Sep 25, 2026
Also in this update: Primary completion date changed from estimate of Aug 31, 2026 to May 1, 2026; Study completion pushed from Aug 31, 2026 to Aug 31, 2027
University of FloridaNot applicable NCT05371041 Registry history of NCT05371041 on ClinicalTrials.gov (opens the registry)
Trial completed
Also in this update: Primary completion date changed from estimate of Jul 30, 2026 to Oct 15, 2026
University of FloridaNot applicable NCT07192757 Registry history of NCT07192757 on ClinicalTrials.gov (opens the registry)
Enrollment closed, study ongoing
Also in this update: Final enrollment: 11 participants (planned 30)
University of FloridaNot applicable NCT06465966 Registry history of NCT06465966 on ClinicalTrials.gov (opens the registry)
Enrollment closed, study ongoing
University of FloridaPhase 1 NCT06389591 Registry history of NCT06389591 on ClinicalTrials.gov (opens the registry)
Enrollment closed, study ongoing
University of FloridaPhase 1 NCT07492316 Registry history of NCT07492316 on ClinicalTrials.gov (opens the registry)
Enrollment closed, study ongoing
University of FloridaPhase 1 NCT05353530 Registry history of NCT05353530 on ClinicalTrials.gov (opens the registry)
Enrollment closed, study ongoing
University of FloridaPhase 1 NCT04837547 Registry history of NCT04837547 on ClinicalTrials.gov (opens the registry)
Enrollment closed, study ongoing
Also in this update: Primary completion moved earlier from Apr 30, 2028 to May 30, 2027
University of FloridaNot applicable NCT05903573 Registry history of NCT05903573 on ClinicalTrials.gov (opens the registry)
Trial completed
Also in this update: Final enrollment: 94 participants (planned 240); Primary completion date changed from estimate of Jun 2030 to Dec 1, 2025
University of FloridaNot specified NCT02114138 Registry history of NCT02114138 on ClinicalTrials.gov (opens the registry)
Trial completed
Also in this update: Final enrollment: 22 participants (planned 40); Study completion date changed from estimate of Jun 30, 2026 to Sep 30, 2026
University of FloridaNot applicable NCT05939336 Registry history of NCT05939336 on ClinicalTrials.gov (opens the registry)
Enrollment closed, study ongoing
Also in this update: Primary and study completion dates pushed to Mar 2027
University of FloridaNot applicable NCT07095920 Registry history of NCT07095920 on ClinicalTrials.gov (opens the registry)
Enrollment closed, study ongoing
Also in this update: Primary completion pushed from Aug 31, 2026 to Oct 31, 2026; Study completion pushed from Aug 31, 2026 to Aug 31, 2027
University of FloridaNot applicable NCT07557745 Registry history of NCT07557745 on ClinicalTrials.gov (opens the registry)
Trial completed
Also in this update: Primary completion date changed from estimate of Aug 2026 to Sep 30, 2026
University of FloridaNot applicable NCT05065008 Registry history of NCT05065008 on ClinicalTrials.gov (opens the registry)
Trial completed
Also in this update: Final enrollment: 37 participants (planned 158); Primary completion date changed from estimate of Dec 2026 to May 20, 2026
University of FloridaNot applicable NCT05913713 Registry history of NCT05913713 on ClinicalTrials.gov (opens the registry)
Primary and study completion pushed from Jul 22, 2026 to Dec 31, 2026
University of FloridaNot applicable NCT06224829 Registry history of NCT06224829 on ClinicalTrials.gov (opens the registry)
| First posted | Trial | Phase | Status |
|---|---|---|---|
| 2026-10-15 | NCT07875907 Repurposing Mefloquine for Pancreatic Cancer Treatment | Phase 1 | Not Yet Recruiting |
| 2026-10-07 | NCT07862400 A Pilot Study on the Efficacy of Oral Low Dose Naltrexone for Vulvodynia | Phase 2 | Not Yet Recruiting |
| 2026-09-28 | NCT07843264 PPI Dosing Per CYP2C19 Genotype | Phase 4 | Not Yet Recruiting |
| Early Phase 1 | 6 | |
| Phase 1 | 14 | |
| Phase 1/2 | 10 | |
| Phase 2 | 31 | |
| Phase 2/3 | 2 | |
| Phase 3 | 2 | |
| Phase 4 | 13 |
Heart Disease (14) · Glioma (13) · Breast Cancer (11) · Coronary Artery Disease (10) · Diabetes (8) · Glioblastoma (8) · Prostate Cancer (8) · Parkinson's Disease (7) · Obesity (6) · Dementia (5)