Tourette Deep Brain Stimulation (DBS) Target Detection & Suppression

StatusActive, Not Recruiting
PhaseNot applicable
Started

Free. We email you which fields changed when ClinicalTrials.gov updates this record.

Track this trial
View on ClinicalTrials.gov ↗

Record History

See every version on ClinicalTrials.gov ↗

  1. Results posted: Sep 25, 2026
    • Primary completion date changed from estimate of Aug 31, 2026 to May 1, 2026
    • Study completion pushed from Aug 31, 2026 to Aug 31, 2027
    • Eligibility criteria expanded, about 31 words
  2. Trial status: Recruiting to Active, Not Recruiting
    • Eligibility criteria expanded, about 71 words
    • Study description expanded, about 118 words
    • Site details revised
    v8
  3. 5 versions Re-verified since Jun 2, 2022, no change to tracked fieldsv3-v7
  4. Start date: May 10, 2022 to Jun 20, 2022v2
  5. Study First Submitted
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The investigators will implant and monitor 8 research subjects with a subcortical closed-loop system for detection and suppression of tics in subjects with medically refractory debilitating Tourette Syndrome. The project will use the FDA-approved "Medtronic Percept PC" device, which is an implantable neurostimulator capable of recording neural signals. The study will target the CM nucleus of the thalamus and the aGPi in each brain hemisphere from each subject and we will connect the two leads placed in each brain hemisphere to two Percept devices.
Trial Details
NCT Number NCT05371041
Lead Sponsor University of Florida
Collaborators: National Institute of Neurological Disorders and Stroke (NINDS)
Conditions
(from sponsor)		 Tourette Syndrome
Related terms Tourette Syndrome
Enrollment 8 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov