Disease landscape

Coronary Artery Disease clinical trials

Get alerts when Coronary Artery Disease trials change

1,224 active trials 625 recruiting 44 Phase 3 625 sponsors 149 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-09-16

What changed in the last 30 days showing 53 of 149 changes on 20 trials

2026-09-03
Trial status changed: Recruiting → Withdrawn
Trial withdrawn: Death of lead PI
Primary completion confirmed: April 2025 (last estimated April 2027)
NCT06994624 Clinical and Biochemical Effects of a Defined Plant-Based Diet on Heart Disease · Georgia State University
2026-09-12
Primary completion pushed: 2026-12-31 → 2027-06-30
Trial sites expanded: 1 → 14 locations
Completion pushed: 2027-06-30 → 2027-12-30
NCT07048808 Investigational Trial to Evaluate XC001 Delivered Via an Cardiac Catheter in Subjects… · XyloCor Therapeutics, Inc. · Phase 2
2026-09-15
Primary completion pushed: 2030-04-30 → 2030-10-01
Completion pushed: 2030-04-30 → 2030-10-01
NCT07491107 Brazilian Prospective Registry of the Inspiron EVO Drug-Eluting Stent in Complex Coronary… · Scitech Produtos Medicos SA
2026-09-16
Primary completion pushed: 2026-12 → 2027-12
Completion pushed: 2027-09 → 2028-09
NCT07080684 Short-Term Dual Antiplatelet Therapy With Early Transi-tion to Low-dose Antiplatelet… · University of Messina · Phase 4
2026-09-05
Primary completion pushed: 2026-03 → 2026-12
Enrollment increased: 150 → 335 participants
Completion pushed: 2026-04 → 2027-02
NCT06481943 A Prospective Research Investigation of Ischemia Using MCG · SB Technology, Inc.
2026-09-15
Primary completion pushed: 2026-07-01 → 2026-12-01
Completion pushed: 2026-07-01 → 2026-12-01
NCT01932411 Factors Affect Outcomes in Cardiovascular Surgery · University of California, Davis
2026-09-15
Primary completion pushed: 2026-06-30 → 2027-06-30
Completion pushed: 2026-06-30 → 2027-06-30
NCT06814587 Hyperpolarized 13C Pyruvate-MRI and FDG-PET in a Single Exam for the Prognosis of… · University of Texas Southwestern Medical Center
2026-08-27
Primary completion pushed: 2024-09 → 2026-01-06
Trial status changed: Unknown → Completed
Completion pushed: 2025-02 → 2026-01-06
NCT06009757 GUIDEX® Versus Launcher™ Guiding Catheter in Percutaneous Coronary Intervention (PCI)… · Tianjin Demax Medical Technology Co., Ltd
2026-08-26
Primary completion pushed: 2026-08-01 → 2026-11-01
Completion pushed: 2026-11-01 → 2027-03-01
NCT07407738 ShockFast Intravascular Lithotripsy Device for Treatment of Calcified Coronary Lesions · Shunmei Medical
2026-09-09
Primary completion pushed: 2026-07 → 2027-05
Completion pushed: 2026-12 → 2028-05
NCT05427786 A Study to Evaluate the Impact of Pre-procedural Intracoronary Nicorandil Injection to… · Korea University Anam Hospital · Phase 4
2026-09-12
Primary completion pushed: 2026-06-15 → 2027-01-20
Recruitment opened
Completion pushed: 2026-10-15 → 2027-05-20
NCT07371806 EFFETCS OF MİNDFULNESS-BASED STRESS REDUCTION İN WOMEN WİTH CORONARY ARTERY DİSEASE · TC Erciyes University
2026-09-10
Primary completion pushed: 2026-03 → 2027-10-31
Interventions modified
Completion pushed: 2026-10 → 2029-06-29
NCT06600178 Study Targeting Myocardial Perfusion and Symptom Relief in Women With SGLT2 Inhibitors… · University of Virginia · Phase 1
2026-09-12
Primary completion pushed: 2026-06-30 → 2027-06-30
Completion pushed: 2026-06-30 → 2027-06-30
NCT06047028 Prognostic Value of Hyperpolarized 13C MRI for Clinical Myocardial Viability · University of Texas Southwestern Medical Center
2026-09-10
Primary completion pushed: 2026-08 → 2027-06
Completion pushed: 2026-08 → 2027-12
NCT05111288 Influence of Pulse Electromagnetic Field Therapy on Myocardial Ischemia · Mayo Clinic
2026-09-09
Primary completion pushed: 2026-08-01 → 2026-12-01
Completion pushed: 2026-08-01 → 2026-12-01
NCT06091319 Florbetaben for Imaging of Vascular Amyloid · Ottawa Heart Institute Research Corporation
2026-09-09
Primary completion pushed: 2026-10 → 2031-09
Primary endpoint(s) modified
Enrollment increased: 100000 → 123000 participants
Completion pushed: 2026-10 → 2031-09
NCT07382414 Electronic Letters to Improve Patient Activation in IHD: The NUDGE-IHD Trial · Tor Biering-Sørensen
2026-08-21
Primary completion pushed: 2025-08 → 2026-03-31
Enrollment closed, study ongoing
NCT06495177 European Survey of Cardiovascular Disease Prevention, Diabetes and Chronic Kidney Disease… · European Society of Cardiology
2026-08-19
Primary completion pushed: 2027-07-31 → 2028-08-31
Completion pushed: 2027-07-31 → 2028-08-31
NCT07031531 Effectiveness of an AI-Enabled Stratified Management System for Premature Coronary Artery… · China National Center for Cardiovascular Diseases
2026-09-11
Primary endpoint(s) modified
Phase changed: not specified → Phase 4
Sponsor changed: [Redacted] → Amgen
Trial status changed: Withheld → Not Yet Recruiting
Enrollment changed: None → 308
Interventions modified
Trial arms changed: 0 → 2
NCT07803679 A Trial Assessing the Effectiveness of Evolocumab in Reducing the Plaque Burden in… · Amgen · Phase 4
2026-09-05
Primary completion pushed: 2026-07-30 → 2027-07-30
Completion pushed: 2026-07-30 → 2027-07-30
NCT01719016 Improvement Assessment of Coronary Flow Dysfunction Using Fundamental Fluid Dynamics · University of Cincinnati

New sponsor entrants, last 90 days sponsors with their first trial in this area

First postedTrialSponsorPhase
2026-09-15 NCT07820800 NMR Metabolomics-Based Risk Assessment and Stratified Digital Health Interventions in… University of Eastern Finland new
2026-09-09 NCT07810621 Post-Induction Low Cardiac Output Syndrome in Coronary Artery Bypass Graft Surgery Ataturk University new
2026-09-09 NCT07808593 Artificial Intelligence - Based Opportunistic Coronary Artery Calcium Scoring on Routine… University of Cologne new
2026-09-09 NCT07811102 Hospital-to-Home Transitional Cardiac Rehabilitation After Cardiac Surgery Cheng-Hsin General Hospital new
2026-09-09 NCT07810686 Smartphone AI Assistance for Prehospital ECG Interpretation École Supérieure de Soins Ambulanciers - College of Higher Education in Prehospital Care new
2026-09-09 NCT07811024 First-in-Human Study Using the SiroMax™ Sirolimus-Coated Balloon Catheter as a… Tonic Medical, Inc. new
2026-09-03 NCT07803471 Yiqi Fumai Lyophilized Injection for Chronic Heart Failure Caused by Coronary Heart… China Academy of Chinese Medical Sciences new
2026-09-02 NCT07799376 Self-Management Support for Acute Coronary Syndrome Patients After Hospital Discharge Nanfang Hospital, Southern Medical University new
2026-09-02 NCT07800741 Flow-Controlled vs. Pressure-Controlled Ventilation in CABG: Effects on Lung Aeration and… Koşuyolu Kartal Heart Training and Research Hospital new
2026-09-01 NCT07797179 Effect of Cold Application on Pain, Ecchymosis, and Comfort After Transradial Coronary… Bezmialem Vakif University new

Active trials by phase

Early Phase 1
4
Phase 1
7
Phase 1/2
3
Phase 2
23
Phase 2/3
4
Phase 3
40
Phase 4
103
Not charted: 1,040 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 1,224

NCT IDTitleSponsorStatusUpdated
Phase 4
NCT07405671 Flecainide Safety in Patients With Coronary Artery Disease and Atrial Fibrillation Universitaire Ziekenhuizen KU Leuven Recruiting 2026-09-15
NCT05427786 A Study to Evaluate the Impact of Pre-procedural Intracoronary Nicorandil Injection to… Korea University Anam Hospital Recruiting 2026-09-08
NCT07572032 Delayed Initiation of ARNI and SGLT2i in Heart Failure With Corrected Aetiology… Kyungsub Song Recruiting 2026-09-02
NCT07796217 Comparison of Clopidogrel-based Antiplatelet Agent Treatment and Aspirin Plus Low Dose… Seoul National University Bundang Hospital Recruiting 2026-09-02
NCT05418556 Tailored Versus Conventional AntiPlaTelet Strategy Intended After OPTIMIZEd Drug Eluting… Asan Medical Center Recruiting 2026-08-31
NCT04416581 Potassium-Competitive Acid Blocker Versus pROton-Pump Inhibitor for GastroproTECTion… Duk-Woo Park, MD Recruiting 2026-08-28
NCT06578234 Hyperemic mYocardial Perfusion by adEnosine at diffeRent Doses Region Skane Recruiting 2026-08-13
NCT05638867 NOAC Therapy Guided by PARIS Risk Score and D-dimer in Patients With ACS After PCI China National Center for Cardiovascular Diseases Recruiting 2026-08-11
NCT07753200 Net Clinical Benefit of Edoxaban Versus Apixaban in Patients With Atrial Fibrillation and… Samsung Medical Center Recruiting 2026-08-10
NCT07362966 Precision Colchicine Intervention to Suppress Atherosclerosis in TET2 Clonal Hematopoiesis Shenyang Northern Hospital Recruiting 2026-06-30
NCT04695106 Dual Antithrombotic Therapy With Dabigatran and Ticagrelor in Patients With ACS and… Medical University of Gdansk Recruiting 2026-06-16
NCT07612774 CAPRA-EVO: a Randomized Serial PCCT Trial of Early Evolocumab After ACS West China Hospital Recruiting 2026-06-09
NCT07614230 SGLT2 Inhibitors on Coronary Atherosclerosis Progression Via Perivascular Adipose Tissue… Junjie Yang Recruiting 2026-05-29
NCT06821191 Comparison of Dual Antiplatelet Therapy De-escalation by Dose Reduction Versus Switching… University of Florida Recruiting 2026-05-12
NCT07225842 The Bridging Antiplatelet Therapy With Cangrelor 2 Study University of Florida Recruiting 2026-05-05
NCT07471867 Effect of ZaStaprazan on Platelet Reactivity of Clopidogrel After PercuTaneous CoronAry… Yonsei University Recruiting 2026-04-24
NCT05618353 The Peri-OPerative COlchicine to Reduce Negative Events (POPCORN) Trial VA Office of Research and Development Recruiting 2026-04-22
NCT07511257 Multicenter Trial of Antithrombotic Strategies in Acute Coronary Syndrome With Coronary… Instituto Nacional de Cardiologia Ignacio Chavez Recruiting 2026-04-09
NCT07476859 Effect of Intravenous Iron on Quality of Life in Older Patients With Acute Coronary… Fundación para la Investigación del Hospital Clínico de Valencia Recruiting 2026-03-24
NCT06451198 IndObufen Versus asPirin After Coronary Drug-eluting Stent implantaTION in Elderly… Shanghai Zhongshan Hospital Recruiting 2026-03-12
NCT07116343 Intrapleural Ropivacaine Infusion in Cardiac Surgery Saint Petersburg State University, Russia Recruiting 2026-03-10
NCT05681702 Tailoring Bleeding Reduction Approaches in Patients Undergoing PCI University of Florida Recruiting 2026-03-09
NCT06916520 Prasugrel Monotherapy Reduced Dose in Acute and Chronic Coronary Syndrome Patients After… J.P.S Henriques Recruiting 2026-03-04
NCT06588595 The Switching Antiplatelet-9 (SWAP-9) Study University of Florida Recruiting 2026-02-25
NCT06543082 MACT (Mono Antiplatelet and Colchicine Therapy) Prospective Multicenter Study CHA University Recruiting 2026-02-18
See all 1,224 active Coronary Artery Disease trials with filters →

Top sponsors by active trials in this area

China National Center for Cardiovascular Diseases (40) · Fundación EPIC (22) · Beijing Anzhen Hospital (18) · Samsung Medical Center (18) · Yonsei University (18) · Nanjing First Hospital, Nanjing Medical University (16) · Seung-Jung Park (15) · Shanghai Zhongshan Hospital (15) · Assiut University (13) · Second Affiliated Hospital, School of Medicine, Zhejiang University (10)

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