University of California, Irvine clinical trial pipeline

8 trials changed in the last 30 days: 0 stopped, 5 with notable changes, 3 with minor changes only.

1. Notable

   Genetically Engineered Natural Killer (NK) Cells With or Without…Genetically Engineered Natural Killer (NK) Cells With or Without Atezolizumab · Non-small Cell Lung Cancer Previously Treated With PD-1 and/or PD-L1 Immune Checkpoint Inhibitors

   Primary and study completion pushed from Jun 14, 2027 to Nov 30, 2028

   University of California, Irvine·Phase 1· NCT05334329· Registry history of NCT05334329 on ClinicalTrials.gov (opens the registry)

   Oct 6, 2026

2. Notable

   Resilience in Reentry: Cognitive-Behavioral Resilience Training for…Resilience in Reentry: Cognitive-Behavioral Resilience Training for Parolees With Adjustment Challenges

   Primary completion pushed from Sep 2026 to Apr 2027

   Also in this update: Study completion pushed from Dec 2026 to Jun 2027

   University of California, Irvine·Not applicable· NCT07167719· Registry history of NCT07167719 on ClinicalTrials.gov (opens the registry)

   Oct 8, 2026

3. Notable

   Project REACH · Exercise in Child Health

   Primary and study completion pushed from Jun 30, 2026 to Dec 31, 2027

   University of California, Irvine·Not applicable· NCT05359991· Registry history of NCT05359991 on ClinicalTrials.gov (opens the registry)

   Oct 2, 2026

4. Notable

   Nicotine · Using Nicotine to Reverse Age-related Auditory…Nicotine · Using Nicotine to Reverse Age-related Auditory Processing Deficits

   Primary endpoint(s) modified

   University of California, Irvine·Not applicable· NCT04971954· Registry history of NCT04971954 on ClinicalTrials.gov (opens the registry)

   Oct 19, 2026

5. Notable

   Empower LCS+ · Empowering Patients' Lung Cancer Screening Uptake…Empower LCS+ · Empowering Patients' Lung Cancer Screening Uptake (Empower LCS/Call+)

   Recruitment opened

   University of California, Irvine·Not applicable· NCT07711691· Registry history of NCT07711691 on ClinicalTrials.gov (opens the registry)

   Sep 21, 2026

• Stopped: an ongoing trial was terminated, suspended or withdrawn.
• Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
• Minor: routine progress and housekeeping, such as sites added or enrollment closed.