University of British Columbia clinical trial pipeline

12 trials changed in the last 30 days: 0 stopped, 3 with notable changes, 9 with minor changes only.

1. Notable

   Buprenorphine/Naloxone Microdosing vs. Standard Dosing in Emergency…Buprenorphine/Naloxone Microdosing vs. Standard Dosing in Emergency Departments

   Primary completion pushed from Dec 2026 to Dec 2027

   Also in this update: Study completion pushed from Jun 2027 to Jun 2028

   University of British Columbia·Phase 2/3· NCT04893525· Registry history of NCT04893525 on ClinicalTrials.gov (opens the registry)

   Updated Sep 24, 2026

2. Notable

   OPTIMal AF-HF · Optimal PharmacoTherapy and Invasive Management…OPTIMal AF-HF · Optimal PharmacoTherapy and Invasive Management of Atrial Fibrillation · Heart Failure

   Primary endpoint(s) modified

   Also in this update: Phase changed: Phase 4 → Phase 3; Interventions modified

   University of British Columbia·Phase 3· NCT07238452· Registry history of NCT07238452 on ClinicalTrials.gov (opens the registry)

   Updated Oct 14, 2026

3. Notable

   Ivabradine for Heart Rate Reduction During Exercise in Healthy…Ivabradine for Heart Rate Reduction During Exercise in Healthy Adults

   Recruitment opened

   University of British Columbia·Early Phase 1· NCT07717710· Registry history of NCT07717710 on ClinicalTrials.gov (opens the registry)

   Updated Oct 9, 2026

• Stopped: an ongoing trial was terminated, suspended or withdrawn.
• Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
• Minor: routine progress and housekeeping, such as sites added or enrollment closed.