Sponsor Pipeline

Eli Lilly and Company Clinical Trial Pipeline

Data updated daily from ClinicalTrials.gov — last refresh 2026-08-16
227
Active Trials
113
Recruiting
90
Phase 3
10
Disease Areas
57
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-08-15 NCT05869903
A Study of Orforglipron (LY3502970) in Adult Participants With Obesity or Overweight With…
Primary endpoint(s) modified
2026-08-13 NCT04527380
A Study of Ixekizumab (LY2439821) in Children With Juvenile Idiopathic Arthritis…
date change Completion pushed: 2028-04 -> 2029-01
2026-08-12 NCT04232553
A Long-term Extension Study of Mirikizumab (LY3074828) in Participants With Crohn's…
date change Completion pushed: 2027-04 -> 2028-03
2026-08-08 NCT03706365
A Study of Abiraterone Acetate Plus Prednisone With or Without Abemaciclib (LY2835219) in…
date change Completion pushed: 2026-06 -> 2026-12
2026-08-08 NCT07157774
Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated…
Trial sites expanded: 772 -> 785 locations
2026-08-08 NCT04280081
A Study of Selpercatinib (LY3527723) in Participants With Advanced Solid Tumors Including…
date change Completion pushed: 2027-11 -> 2028-11
2026-08-08 NCT06890598
Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With…
Trial sites expanded: 366 -> 370 locations
2026-08-07 NCT07353931
Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee…
Trial sites reduced: 161 -> 152 locations
2026-08-07 NCT07369011
A Study of Eloralintide (LY3841136) in Participants With Obstructive Sleep Apnea and…
Trial sites reduced: 129 -> 115 locations
2026-08-07 NCT07392190
A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are…
Trial sites expanded: 173 -> 188 locations
2026-08-07 NCT07174336
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in…
Trial sites expanded: 346 -> 353 locations
2026-08-07 NCT07287098
A Study of Imlunestrant (LY3484356) in Premenopausal Women With Estrogen…
Trial sites expanded: 78 -> 86 locations
2026-08-07 NCT07223593
Efficacy and Safety of Orforglipron in Participants With Peripheral Artery Disease
Trial sites expanded: 154 -> 157 locations
2026-08-06 NCT03952559
A Study of Baricitinib (LY3009104) in Children and Adolescents With Atopic Dermatitis
Trial completed
2026-08-01 NCT06993792
A Master Protocol for Orforglipron (LY3502970) in Participants With Obesity or Overweight…
Enrollment increased: 1200 -> 1400 participants
2026-07-31 NCT05882045
A Study of Retatrutide (LY3437943) in Participants With Obesity and Cardiovascular Disease
Trial completed
2026-07-31 NCT07533019
A Study of LY4005130 in Adult Participants With Non-Segmental Vitiligo
Enrollment increased: 60 -> 66 participants
2026-07-31 NCT07174336
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in…
Enrollment reduced: 920 -> 800 participants
2026-07-31 NCT07174336
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in…
Trial sites expanded: 338 -> 346 locations
2026-07-31 NCT05929079
A Study of Retatrutide (LY3437943) in Participants With Type 2 Diabetes Mellitus Who Have…
Trial completed
Showing 20 of 57 changes detected in the last 30 days.
New Trial Filings, Last 30 Days
First PostedTrialPhaseStatus
2026-08-14 NCT07765498 A Study of LY4355756 in Healthy Participants Phase 1 Not Yet Recruiting
2026-08-14 NCT07765511 A Study of Macupatide (LY3532226) in Participants With Obesity or Overweight Without Type… Phase 1 Not Yet Recruiting
2026-08-12 NCT07759245 A Study of Brenipatide (LY3537031) in Adult Participants With Moderate-to-Severe Chronic… Phase 2 Not Yet Recruiting
2026-07-31 NCT07738614 A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight Phase 1 Not Yet Recruiting
Active Trials by Phase
Phase 4
10
Phase 3
89
Phase 2/3
1
Phase 2
45
Phase 1/2
5
Phase 1
71
Not specified
6
Active Trials — top 25 of 227
NCT IDTitleConditionStatus
Phase 4
NCT06876649 A Master Protocol to Evaluate the Long-Term Safety of (LY3527727) Pirtobrutinib Chronic Lymphocytic Leukemia Recruiting
NCT06876662 A Study of (LY3527727) Pirtobrutinib in Participants With Previously Treated Chronic… Chronic Lymphocytic Leukemia Recruiting
NCT07438444 A Study of Tirzepatide (LY3298176) in Adult Participants in India With Either Type 2… Diabetes Mellitus, Type 2 Recruiting
NCT06857942 A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation… Psoriasis Recruiting
NCT06864026 A Study to Investigate Effectiveness of Tirzepatide Following Initiation of Ixekizumab in… Psoriatic Arthritis Recruiting
NCT07247084 A Study of Tirzepatide (LY3298176) Compared With Standard of Care in Adult Participants… Obesity Recruiting
NCT07218341 A Study of Pirtobrutinib (LY3527727) in Participants With Chronic Lymphocytic… Chronic Lymphocytic Leukemia Recruiting
NCT05433584 A Study of Tirzepatide Compared With Intensified Conventional Care in Adult Participants… Type 2 Diabetes Active, Not Recruiting
NCT07006792 A Study to See How Well Lebrikizumab Works in Adults and Adolescents With Moderate Atopic… Atopic Dermatitis Active, Not Recruiting
NCT07612267 A Study to Measure Mirikizumab Levels in Breast Milk of Lactating Participants Receiving… Lactation Not Yet Recruiting
Phase 3
NCT07142954 Epidemiology and Biomarker Study in Alzheimer's Disease Alzheimer Disease Recruiting
NCT07602582 A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM… Alzheimer Disease Recruiting
NCT07218380 A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract Carcinoma, Transitional Cell Recruiting
NCT05723198 A Study of Baricitinib (LY3009104) in Children From 6 Years to Less Than 18 Years of Age… Areata Alopecia Recruiting
NCT06119581 A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without… Carcinoma, Non-Small-Cell Lung Recruiting
NCT06672549 A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040) Obesity Recruiting
NCT06672939 A Study of Orforglipron (LY3502970) in Adolescent Participants With Obesity, or… Obesity Recruiting
NCT06338995 A Study of Lebrikizumab (LY3650150) in Participants With Chronic Rhinosinusitis and Nasal… Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) Recruiting
NCT06937086 Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With… Ulcerative Colitis Recruiting
NCT06937099 Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to… Crohn's Disease Recruiting
NCT07153471 A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and… Osteoarthritis Recruiting
NCT07165028 A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated… Metabolic Dysfunction-Associated Steatotic Liver Disease Recruiting
NCT07174336 A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in… Breast Neoplasms Recruiting
NCT07202884 A Study of Orforglipron in Female Participants With Stress Urinary Incontinence Who Have… Urinary Incontinence,Stress Recruiting
NCT07213804 A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With… Ovarian Neoplasms Recruiting
See all 227 active Eli Lilly and Company trials with filters →
Disease Areas
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