| Detected | Trial | Change |
|---|---|---|
| 2026-06-04 | NCT07574723 Tirzepatide Titration to Reduce Side Effects in Individuals With Obesity |
Primary endpoint(s) modified |
| 2026-06-04 | NCT06162715 GLP-1 Receptor Agonists Post-Bariatric Surgery (GRABS) Pilot Trial |
Primary endpoint(s) modified |
| 2026-05-30 | NCT07154719 GLP-1R Actions on Muscle and the Skeleton |
date change Primary completion pushed: 2026-12-01 -> 2027-02-01 |
| 2026-05-30 | NCT07154719 GLP-1R Actions on Muscle and the Skeleton |
date change Completion pushed: 2026-12-01 -> 2027-05-01 |
| 2026-05-23 | NCT06635057 A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes During Ramadan |
Trial completed |
| 2026-05-23 | NCT06635057 A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes During Ramadan |
Enrollment increased: 130 -> 166 participants |
| 2026-05-21 | NCT07559500 Tirzepatide s Dopaminergic Effects in Alcohol Use Disorders (AUD) |
Recruitment opened |
| 2026-05-20 | NCT07299084 A Study to Evaluate the Effect of Fasting Duration and Tirzepatide Withholding on the… |
overall status: "Recruiting" → "Active Not Recruiting" |
| 2026-05-20 | NCT06162715 GLP-1 Receptor Agonists Post-Bariatric Surgery (GRABS) Pilot Trial |
date change Primary completion moved earlier: 2027-05 -> 2027-01-01 |
| 2026-05-20 | NCT07588438 Efficacy, Safety, and Tolerability of Tirzepatide in Real-World Conditions in Paraguay. |
Recruitment opened |
| 2026-05-19 | NCT06803888 Bariatric Surgery vs. Semaglutide vs. Tirzepatide |
overall status: "Recruiting" → "Active Not Recruiting" |
| 2026-05-15 | NCT07463846 A Study to Evaluate ALN-2232 in Participants With Obesity |
date change Primary completion moved earlier: 2028-02-01 -> 2027-04-27 |
| 2026-05-15 | NCT06143956 A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in… |
Enrollment increased: 1217 -> 1481 participants |
| 2026-05-15 | NCT06143956 A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in… |
Trial arms changed: 5 -> 6 |
| 2026-05-15 | NCT06143956 A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in… |
date change Primary completion pushed: 2026-06 -> 2027-09 |
| 2026-05-15 | NCT06143956 A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in… |
date change Completion pushed: 2026-09 -> 2028-02 |
| 2026-05-14 | NCT07417618 INcreTin-based thERapies for Cardiovascular Event PrevenTion in Patients With and Without… |
Primary endpoint(s) modified |
| 2026-05-14 | NCT07417618 INcreTin-based thERapies for Cardiovascular Event PrevenTion in Patients With and Without… |
date change Primary completion pushed: 2026-03 -> 2026-05-22 |
| 2026-05-14 | NCT07417618 INcreTin-based thERapies for Cardiovascular Event PrevenTion in Patients With and Without… |
date change Completion pushed: 2026-03 -> 2026-05-22 |
| 2026-05-14 | NCT06588296 Ixekizumab Concomitantly Administered With Tirzepatide in Adults With Psoriatic Arthritis… |
Trial completed |
| First Posted | Trial | Phase | Status |
|---|---|---|---|
| 2026-06-10 | NCT07640139 Estimating the Impact of Obesity Medications on Clinical and Economic Outcomes | Enrolling by Invitation | |
| 2026-06-05 | NCT07630454 Tirzepatide on Atrial Fibrillation Recurrence After Catheter Ablation in Patients With… | Phase 4 | Not Yet Recruiting |
| 2026-06-02 | NCT07619508 Tirzepatide vs Semaglutide in Individuals at Cardiovascular Risk But Without Diabetes. | Active, Not Recruiting | |
| 2026-05-22 | NCT07602699 Multi-Site Trial of Tirzepatide for Smoking Cessation | Phase 2 | Recruiting |
| 2026-05-22 | NCT07605247 Tirzepatide in the Treatment of Endometrial Cancer | Phase 2 | Not Yet Recruiting |
| 2026-05-15 | NCT07588984 GLP-1 Medication & Behavioral Health Programs on Weight & Metabolic Outcomes: FLOURISH… | Not Yet Recruiting | |
| 2026-05-14 | NCT07588438 Efficacy, Safety, and Tolerability of Tirzepatide in Real-World Conditions in Paraguay. | Phase 4 | Recruiting |
| NCT ID | Title | Condition | Status |
|---|---|---|---|
| Phase 4 | |||
| NCT07423247 | Tirzepatide (Spartina) in Obese Kidney Transplant Recipients | Tirzepatide | Recruiting |
| NCT05681299 | Effects of GH and Lirglutide on AgRP | Healthy | Recruiting |
| NCT06774079 | Glucagon-like Peptide-1 Receptor Agonist (GLP-1 RA) and Diet in Inflammatory Bowel… | Crohn Disease | Recruiting |
| NCT07247084 | A Study of Tirzepatide (LY3298176) Compared With Standard of Care in Adult Participants… | Obesity | Recruiting |
| NCT06657209 | Normal-weight Diabetes: Adipocyte-directed Therapy With Pioglitazone or Tirzepatide | Diabetes Mellitus, Type 2 | Recruiting |
| NCT07096908 | Tirzepatide Use in People With Obesity and Type 1 Diabetes | Type1diabetes | Recruiting |
| NCT04575844 | Effects of Exercise and GLP-1 Agonism on Muscle Microvascular Perfusion and Insulin… | Metabolic Syndrome | Recruiting |
| NCT06721507 | 2024 Tirzepatide-Bariatric Surgery | Obesity and Obesity-related Medical Conditions | Recruiting |
| NCT07438444 | A Study of Tirzepatide (LY3298176) in Adult Participants in India With Either Type 2… | Diabetes Mellitus, Type 2 | Recruiting |
| NCT07588438 | Efficacy, Safety, and Tolerability of Tirzepatide in Real-World Conditions in Paraguay. | Obesity | Recruiting |
| NCT07154719 | GLP-1R Actions on Muscle and the Skeleton | Musculoskeletal Abnormalities | Recruiting |
| NCT06857942 | A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation… | Psoriasis | Recruiting |
| NCT07218445 | The Effect of Tirzepatide on Menopausal Vasomotor Symptoms and Biological Aging in… | Obesity | Recruiting |
| NCT06864026 | A Study to Investigate Effectiveness of Tirzepatide Following Initiation of Ixekizumab in… | Psoriatic Arthritis | Recruiting |
| NCT06801015 | Effects of Long-Acting GLP-1 (Glucagon-like Peptide-1) or Dual Incretin (GLP-1 and GIP… | Obesity | Active, Not Recruiting |
| NCT07257484 | Tirzepatide's Role in Postmenopausal HR+ Breast Cancer Survivors | Obesity (Disorder) | Not Yet Recruiting |
| NCT07483801 | DECODE - Haemodynamic Effects Of Semaglutide and Tirzepatide - a Series of Pilot Studies | Cardiovascular Diseases | Not Yet Recruiting |
| NCT07555730 | AI-assisted Multi-domain Lifestyle Versus Tirzepatide for Weight Loss Maintenance in… | Overweight or Obesity; Type 2 Diabetes | Not Yet Recruiting |
| NCT02944500 | Saxenda: Underlying Mechanisms and Clinical Outcomes | Obesity | Active, Not Recruiting |
| NCT03856632 | Liraglutide Effect in Atrial Fibrillation | Atrial Fibrillation | Active, Not Recruiting |
| NCT07554638 | Incretin Therapies in Obesity-related HFpEF | Heart Failure, Diastolic | Not Yet Recruiting |
| NCT06803888 | Bariatric Surgery vs. Semaglutide vs. Tirzepatide | Obesity and Obesity-related Medical Conditions | Active, Not Recruiting |
| NCT07630454 | Tirzepatide on Atrial Fibrillation Recurrence After Catheter Ablation in Patients With… | Atrial Fibrillation | Not Yet Recruiting |
| Phase 3 | |||
| NCT06630585 | GIP/GLP-1RA as Adjunctive to Automated Insulin Delivery in Adults With Type 1 Diabetes | Type 1 Diabetes (T1D) | Recruiting |
| NCT06246799 | Comparative Effectiveness of Two Initial Combination Therapies in Patients With Recent… | Type 2 Diabetes (Adult Onset) | Recruiting |