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A Study to Investigate Effectiveness of Tirzepatide Following Initiation of Ixekizumab in Participants With Active Psoriatic Arthritis and Overweight or Obesity in Clinical Practice (TOGETHER AMPLIFY-PsA)

StatusRecruiting
PhasePhase 4
Started2025-03-06
View on ClinicalTrials.gov ↗
The main purpose of this study is to assess the effectiveness of adding tirzepatide to ixekizumab therapy in standard clinical practice in participants with active PsA and obesity or overweight with at least 1 weight-related comorbidity. The study will last up to 12 months.

Amendment record

Amended 13 times since 2025-03-04; most recent filed 2026-06-09. Every amendment is listed below.

Dates here are the day the sponsor filed the amendment, not the day ClinicalTrials.gov published it. Version history last read from ClinicalTrials.gov on 2026-08-31.

2026-06-09
Amendment Study Status, Study Description, Contacts/Locations, References v13
2026-02-09
Amendment Study Status, Contacts/Locations v12
2025-12-23
Amendment Study Status, Contacts/Locations v11
2025-11-21
Amendment Study Status, Contacts/Locations v10
2025-10-08
Amendment Study Status, Contacts/Locations v9
2025-09-25
Amendment Study Status, Contacts/Locations v8
2025-08-25
Amendment Study Status, Contacts/Locations v7
2025-07-17
Amendment Study Status, Contacts/Locations v6
2025-06-18
Amendment Study Status, Contacts/Locations v5
2025-06-03
Amendment Study Status, Contacts/Locations v4
2025-04-17
Amendment Study Status, Contacts/Locations v3
2025-03-27
Amendment Not Yet Recruiting→Recruiting Study Status, Contacts/Locations v2
2025-03-13
Amendment Study Identification, Study Status, References v1
2025-03-04
Original filing
Trial Details
NCT Number NCT06864026
Lead Sponsor Eli Lilly and Company
Conditions Psoriatic Arthritis, Overweight or Obesity
Enrollment 200 participants
Start Date 2025-03-06
Primary Completion 2027-11 (estimated)
Study Completion 2027-11 (estimated)
Updated on ClinicalTrials.gov 2026-06-11