Wake Forest University Health Sciences clinical trial pipeline

28 trials changed in the last 30 days: 1 stopped, 11 with notable changes, 16 with minor changes only.

1. Stopped

   Sage Guard for Oral Cavity Protection

   Withdrawn before enrolling

   Sponsor's reason: Funding constraints

   Also in this update: Primary completion pushed from Dec 2027 to Nov 2028; Start date pushed from Sep 2026 to Aug 2027

   Wake Forest University Health Sciences·Not applicable· NCT07806812· Registry history of NCT07806812 on ClinicalTrials.gov (opens the registry)

   Updated Sep 28, 2026

2. Notable

   GLOW · GLP-1s to Enhance Lasting Optimal Weight

   Primary completion pushed from Oct 30, 2026 to Oct 30, 2027

   Also in this update: Primary endpoint(s) modified; Study completion pushed from Dec 31, 2026 to Dec 31, 2027; and 1 more change in the last 30 days

   Wake Forest University Health Sciences·Phase 4· NCT06861439· Registry history of NCT06861439 on ClinicalTrials.gov (opens the registry)

   Updated Oct 2, 2026

3. Notable

   Lumbar Drain With Intrathecal Nicardipine in Aneurysmal…Lumbar Drain With Intrathecal Nicardipine in Aneurysmal Subarachnoid Hemorrhage

   Primary and study completion pushed from Mar 2027 to Mar 2028

   Wake Forest University Health Sciences·Phase 4· NCT07246629· Registry history of NCT07246629 on ClinicalTrials.gov (opens the registry)

   Updated Oct 1, 2026

4. Notable

   TNK-FLOW · Intra-Arterial Tenecteplase Following Endovascular…TNK-FLOW · Intra-Arterial Tenecteplase Following Endovascular Thrombectomy for Large Vessel Occlusion Stroke

   Primary completion pushed from Sep 2026 to Jun 2028

   Also in this update: Study completion pushed from Dec 2026 to Jun 2028

   Wake Forest University Health Sciences·Phase 2· NCT06781385· Registry history of NCT06781385 on ClinicalTrials.gov (opens the registry)

   Updated Sep 25, 2026

5. Notable

   ADAPT-MCH · ADAPTive Intervention to Improve Food Security and…ADAPT-MCH · ADAPTive Intervention to Improve Food Security and Maternal-Child Health

   Primary completion pushed from Nov 2026 to Aug 2027

   Also in this update: Study completion pushed from Feb 2027 to Nov 2027

   Wake Forest University Health Sciences·Not applicable· NCT06942598· Registry history of NCT06942598 on ClinicalTrials.gov (opens the registry)

   Updated Oct 2, 2026

6. Notable

   CARE-CP · Cardiovascular Ambulatory Rapid Evaluation · Chest Pain)

   Primary completion pushed from Sep 2026 to Sep 2027

   Also in this update: Study completion pushed from Sep 2027 to Sep 2028

   Wake Forest University Health Sciences·Not applicable· NCT05897632· Registry history of NCT05897632 on ClinicalTrials.gov (opens the registry)

   Updated Sep 30, 2026

7. Notable

   Mindfulness in Nonflaccid Facial Paralysis

   Primary and study completion pushed from Jan 2027 to Apr 2028

   Also in this update: Start date pushed from Sep 2026 to Apr 2027

   Wake Forest University Health Sciences·Not applicable· NCT07127016· Registry history of NCT07127016 on ClinicalTrials.gov (opens the registry)

   Updated Sep 30, 2026

8. Notable

   Intramedullary Calcium Sulfate Antibiotic Depot

   Enrollment reduced: 497 → 242 participants

   Wake Forest University Health Sciences·Phase 3· NCT05766670· Registry history of NCT05766670 on ClinicalTrials.gov (opens the registry)

   Updated Oct 14, 2026

9. Notable

   Pelashield vs Xeroform

   Recruitment opened

   Wake Forest University Health Sciences·Phase 4· NCT07734519· Registry history of NCT07734519 on ClinicalTrials.gov (opens the registry)

   Updated Oct 1, 2026

10. Notable

    CATSINDO Trial - Clinical and Translational Study in Newly…CATSINDO Trial - Clinical and Translational Study in Newly Diagnosed Osteosarcoma

    Recruitment opened

    Also in this update: Start date moved earlier from Oct 2026 to Sep 2026

    Wake Forest University Health Sciences·Phase 2· NCT07560826· Registry history of NCT07560826 on ClinicalTrials.gov (opens the registry)

    Updated Sep 25, 2026

11. Notable

    Pelvic Physical Therapy for Sexual Dysfunction in Gynecologic…Pelvic Physical Therapy for Sexual Dysfunction in Gynecologic Oncology Survivors

    Results posted: Sep 29, 2026

    Wake Forest University Health Sciences·Not applicable· NCT05242770· Registry history of NCT05242770 on ClinicalTrials.gov (opens the registry)

    Updated Sep 29, 2026

12. Notable

    UPBEAT · Understanding and Predicting Breast Cancer Events After…UPBEAT · Understanding and Predicting Breast Cancer Events After Treatment

    Primary and study completion moved earlier from Jul 31, 2034 to Jul 31, 2032

    Wake Forest University Health Sciences·Not applicable· NCT02791581· Registry history of NCT02791581 on ClinicalTrials.gov (opens the registry)

    Updated Sep 28, 2026

• Stopped: an ongoing trial was terminated, suspended or withdrawn.
• Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
• Minor: routine progress and housekeeping, such as sites added or enrollment closed.