Sponsor pipeline

Sunnybrook Health Sciences Centre clinical trial pipeline

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Data updated daily from ClinicalTrials.gov, last refresh 2026-10-16

What changed in the last 30 days

2 trials changed in the last 30 days: 0 stopped, 0 with notable changes, 2 with minor changes only.

  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.

New trial filings, last 30 days

First postedTrialPhaseStatus
2026-09-18 NCT07828730 Sparrow App Guided Evaluation (SAGE) Vanguard Trial for Aortic Stenosis in Adults Aged… Not Yet Recruiting

Active trials by phase

Early Phase 1
1
Phase 1
12
Phase 1/2
1
Phase 2
16
Phase 2/3
1
Phase 3
10
Phase 4
4
Not charted: 108 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 153

NCT IDTitleConditionStatusUpdated
Phase 4
NCT06423716 Effect of peRiopErative duLoxetIne Administration on Opioid Consumption Following Total… Knee Osteoarthritis Recruiting 2026-08-12
NCT07245732 Oral Versus Intramuscular Steroid Use to Control Rheumatoid Arthritis Flares Rheumatoid Arthritis (RA) Recruiting 2026-04-13
NCT04289142 Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery Patients Delirium Recruiting 2025-12-01
NCT03480061 Dexmedetomidine to Reduce the Incidence of POCD After Open Cardiac Surgery Delirium Active, Not Recruiting 2024-12-24
Phase 3
NCT06781697 InTRavenous kEtAmine and immerSive virtUal Reality to Treat dEpression Treatment Resistant Depression Recruiting 2026-08-13
NCT05867472 Advancing Brain Outcomes in Pediatric Critically Ill Patients Sedated With Volatile… Intensive Care Units, Pediatric Recruiting 2026-02-04
NCT04516057 Nabilone for Agitation Blinded Intervention Trial Alzheimer Disease Recruiting 2026-01-28
NCT06055257 Combination Therapy: Hyperbaric Oxygen and PENTOCLO for Treatment of Osteoradionecrosis… Osteoradionecrosis Recruiting 2025-09-12
NCT06915857 Topical Betamethasone Versus Moisturizer in Preventing Radiation Dermatitis in… Breast Cancer Recruiting 2025-05-21
NCT03559114 PROphylaxis for Venous ThromboEmbolism in Severe Traumatic Brain Injury (PROTEST) Traumatic Brain Injury Recruiting 2024-09-19
NCT07191145 Eary Infusion of Eptinezumab for TreatmEnt of ACute Post-Traumatic Headaches (ELITE-ACT) Post Traumatic Headache Not Yet Recruiting 2026-08-13
NCT07454707 Testing a New Treatment Strategy to Improve Secondary Stroke Prevention for Older Adults… Stroke, Ischemic Not Yet Recruiting 2026-03-06
NCT04415060 SedAting With Volatile Anesthetics Critically Ill COVID-19 Patients in ICU: Effects On… Covid19 Active, Not Recruiting 2026-02-09
NCT02261415 The HeLiX (Hemorrhage During Liver Resection: traneXamic Acid) Trial Cancer Active, Not Recruiting 2022-10-26
Phase 2/3
NCT04654338 2 Ablative RadioTherapy Treatments for Prostate Cancer Prostate Cancer Recruiting 2023-06-27
Phase 2
NCT07764497 Hepatic Arterial Infusion Chemotherapy in Patients With Inoperable Colorectal Cancer… Colorectal Adenocarcinoma Metastatic in the Liver Recruiting 2026-08-14
NCT06014424 Cannabidiol Medication Intervention Trial Alzheimer Disease Recruiting 2026-07-31
NCT07477431 Levetiracetam for Persons at Risk for Alzheimer's Disease Hippocampal Hyperactivation Recruiting 2026-07-29
NCT06072898 A Randomized Neuroimaging Trial of Psilocybin in Depression Depressive Disorder Recruiting 2026-03-30
NCT07476794 Daily Temozolomide for Elderly Patients With Unmethylated MGMT- Promoter Newly Diagnosed… Glioblastoma Recruiting 2026-03-17
NCT07478289 A Phase II Trial Evaluating Radiation Boost to Painful Spinal Metastases Spine Metastasis Recruiting 2026-03-17
NCT06016387 Tucatinib, Trastuzumab and Capecitabine With Brain and/or Spinal Radiotherapy (XRT) in… HER2-positive Breast Cancer Recruiting 2026-02-23
NCT07279740 Combined Brain Stimulation and Methylphenidate Treatment for Apathy in Dementia Alzheimer s Disease Recruiting 2025-12-12
NCT07162246 Combined Gamma Knife/Linac Radiosurgery for Large Brain Tumors / Metastases Brain (Nervous System) Cancers Recruiting 2025-09-09
NCT06185972 Novel Magnetic Resonance Imaging-Guided Ultrasound-Stimulated Microbubble Radiation… Breast Cancer Recruiting 2024-09-27

Disease areas by active trials, top 10 of 32

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