Sponsor pipeline

Regeneron Pharmaceuticals clinical trial pipeline

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116 active trials 70 recruiting 37 Phase 3 10 disease areas 51 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-08-28

What changed in the last 30 days showing 45 of 51 changes on 20 trials

2026-08-18
Trial terminated
Trial terminated: Unfavorable benefit-risk assessment
Enrollment reduced: 72 → 1 participants
Primary completion moved earlier: 2028-06-28 → 2026-07-21
Completion moved earlier: 2028-06-28 → 2026-07-21
NCT07218770 A Study of REGN7041 for Active Noninfectious Uveitis in Adult Participants · Phase 1/2
2026-08-15
Primary completion pushed: 2029-01-23 → 2031-04-30
Primary endpoint(s) modified
Enrollment increased: 470 → 580 participants
Completion pushed: 2029-01-23 → 2031-04-30
NCT06149286 A Trial to Find Out if Odronextamab Combined With Lenalidomide is Safe and Works Better… · Phase 3
2026-08-13
Primary completion pushed: 2027-10-16 → 2029-05-31
Recruitment opened
Completion pushed: 2028-06-30 → 2029-09-20
NCT07675811 A Study to Evaluate the Efficacy and Safety of Fel d 1 Monoclonal Antibodies in Adult and… · Phase 3
2026-07-30
Primary completion pushed: 2027-11-29 → 2028-07-31
Trial sites expanded: 218 → 223 locations
Completion pushed: 2032-05-21 → 2033-04-09
NCT06541704 A Study Investigating Subcutaneously Administered Pozelimab in Combination With… · Phase 3
2026-08-11
Primary completion pushed: 2026-04-20 → 2026-08-24
NCT06161441 A Trial to Learn if the Combination of Fianlimab, Cemiplimab, and Chemotherapy is Safe… · Phase 2
2026-08-08
Primary completion pushed: 2026-05-21 → 2026-08-21
Completion pushed: 2026-05-21 → 2026-08-21
NCT05568459 A Trial That Evaluates Disease Characteristics in Hemophilia B Adult Male Participants…
2026-08-26
Recruitment opened
Trial sites expanded: 0 → 8 locations
NCT07626411 Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation · Phase 3
2026-08-25
Enrollment closed, study ongoing
Trial sites reduced: 50 → 47 locations
NCT06465329 A Study of Cemiplimab Plus Chemotherapy Versus Cemiplimab Plus Chemotherapy Plus Other… · Phase 2
2026-08-26
Recruitment opened
Enrollment increased: 64 → 88 participants
Primary completion moved earlier: 2027-05-27 → 2027-02-08
Completion moved earlier: 2027-05-27 → 2027-02-08
NCT07526116 A First in Human Study to Assess Safety, Tolerability and Pharmacokinetics of a Single… · Phase 1
2026-08-21
Recruitment opened
Trial sites expanded: 0 → 5 locations
NCT07685808 Study of Olatorepatide in Adult Participants Living With Overweight or Obesity Without… · Phase 2
2026-07-30
Trial completed
Completion moved earlier: 2026-11-03 → 2026-07-09
NCT06548100 A Study of the Safety of Mibavademab in Pediatric and Adult Participants Switching From… · Phase 3
2026-08-06
Recruitment opened
Primary completion pushed: 2030-09-20 → 2030-10-27
Trial sites expanded: 0 → 4 locations
Completion pushed: 2030-09-20 → 2030-10-27
NCT07594106 REGN15505 (PSMAx4-1BB) Alone or in Combination With Cemiplimab or REGN4336 (PSMAxCD3) in… · Phase 1/2
2026-07-30
Recruitment opened
NCT07609940 Adult Outpatient Linvoseltamab With Tocilizumab Prophylaxis to Mitigate the Risk of… · Phase 4
2026-08-13
Enrollment closed, study ongoing
NCT06693531 A U.S. Registry of Eosinophilic Esophagitis Pediatric, Adolescent and Adult Patients…
2026-08-13
Enrollment increased: 220 → 297 participants
Primary completion moved earlier: 2028-10-30 → 2028-06-30
Completion moved earlier: 2028-10-30 → 2028-06-30
Trial arms changed: 5 → 6
NCT06787612 Investigation of Ubamatamab Combination Therapy in Adult Participants With… · Phase 2
2026-08-21
Trial sites expanded: 172 → 178 locations
NCT06091865 A Study to Compare How Well Odronextamab Combined With Chemotherapy Works and How Safe it… · Phase 3
2026-08-22
Trial sites expanded: 32 → 35 locations
NCT06769698 A Study to See if Giving Fianlimab and Cemiplimab Together is Better Than Cemiplimab… · Phase 2
2026-08-20
Trial sites expanded: 13 → 17 locations
NCT07318610 Reducing Adverse Vascular Outcomes With Factor XI Inhibition in Adult Participants With… · Phase 3
2026-08-21
Trial sites expanded: 24 → 28 locations
NCT04590326 A Study to Find Out How Safe REGN5668 is and How Well it Works In Adult Women When Given… · Phase 1/2
2026-08-21
Trial sites expanded: 74 → 77 locations
NCT07175428 Safety in Adult Participants With Atrial Fibrillation Who Are Treated With Anticoagulation · Phase 2

New trial filings, last 30 days

First postedTrialPhaseStatus
2026-08-21 NCT07780110 Compassionate Use of Vonsetamig Available
2026-08-12 NCT07759167 Study of 3 Monoclonal Antibodies (REGN9933, REGN7508, and REGN9533) in Adult Participants… Phase 1 Not Yet Recruiting
2026-08-07 NCT07753148 Safety and Tolerability of REGN17235 in Adult Participants With Clonal Cytopenia of… Phase 1 Not Yet Recruiting

Active trials by phase

Phase 1
17
Phase 1/2
22
Phase 2
25
Phase 2/3
2
Phase 3
35
Phase 4
4
Not charted: 11 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 116

NCT IDTitleConditionStatusUpdated
Phase 4
NCT07609940 Adult Outpatient Linvoseltamab With Tocilizumab Prophylaxis to Mitigate the Risk of… Relapsed/Refractory Multiple Myeloma (RRMM) Recruiting 2026-08-20
NCT07142343 A Study to Test the Safety of Pozelimab in Pediatric Participants 1 to 5 Years of Age… CHAPLE Disease Recruiting 2026-04-13
NCT06572228 Efficacy of Dupilumab Added to Medium Dose Inhaled Corticosteroid/Long-acting… Asthma Active, Not Recruiting 2026-05-22
NCT07587658 This After Market Study is Seeing if Dupilumab Plus Usual Standard of Care (SOC) is… Chronic Obstructive Pulmonary Disease (COPD) Not Yet Recruiting 2026-05-14
Phase 3
NCT06541704 A Study Investigating Subcutaneously Administered Pozelimab in Combination With… Age-related Macular Degeneration (AMD) Recruiting 2026-08-25
NCT07626411 Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation Atrial Fibrillation (AF) Recruiting 2026-08-25
NCT06091865 A Study to Compare How Well Odronextamab Combined With Chemotherapy Works and How Safe it… Diffuse Large B-cell Lymphoma (DLBCL) Recruiting 2026-08-20
NCT07112378 A Study of Dupilumab in Small Children With an Allergic Condition of the Esophagus (Food… Eosinophilic Esophagitis (EoE) Recruiting 2026-08-20
NCT07410117 REGN7508 in Adult Participants for Prevention of Cancer-Associated Thrombosis Cancer-Associated Thrombosis (CAT) Recruiting 2026-08-20
NCT06246916 A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants… Melanoma Recruiting 2026-08-19
NCT07213778 REGN7508 Versus Acetylsalicylic Acid (ASA) for Venous Thromboprophylaxis After Total Knee… Symptomatic Venous Thromboembolism (VTE) Recruiting 2026-08-19
NCT07318610 Reducing Adverse Vascular Outcomes With Factor XI Inhibition in Adult Participants With… Peripheral Artery Disease (PAD) Recruiting 2026-08-19
NCT07493304 Treatment and Secondary Prevention of Venous Thromboembolism (VTE) in Adult Participants… Venous Thromboembolism (VTE) Recruiting 2026-08-19
NCT07220785 Efficacy and Safety of Mibavademab in Adult and Pediatric Patients With Generalized… Generalized Lipodystrophy Recruiting 2026-08-18
NCT07393282 A Study to Compare Linvoseltamab and Daratumumab Treatment in High-Risk Smoldering… High Risk Smoldering Multiple Myeloma (HR-SMM) Recruiting 2026-08-18
NCT06585410 Study of Intralesional Cemiplimab in Adult Patients With Early Stage Cutaneous Squamous… Cutaneous Squamous Cell Carcinoma (CSCC) Recruiting 2026-08-17
NCT06149286 A Trial to Find Out if Odronextamab Combined With Lenalidomide is Safe and Works Better… Relapsed/Refractory Follicular Lymphoma Recruiting 2026-08-14
NCT07675811 A Study to Evaluate the Efficacy and Safety of Fel d 1 Monoclonal Antibodies in Adult and… Allergic Conjunctivitis Recruiting 2026-08-12
NCT06091254 A Trial to Learn if Odronextamab is Safe and Well-Tolerated and How Well it Works… Follicular Lymphoma (FL) Recruiting 2026-08-10
NCT07154745 A Study to Evaluate How Pozelimab + Cemdisiran Combination Therapy Works in Adult… Paroxysmal Nocturnal Hemoglobinuria Recruiting 2026-08-05
NCT05744921 A Study in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) to Evaluate How… Paroxysmal Nocturnal Hemoglobinuria Recruiting 2026-07-30
NCT07015905 REGN7508 Versus Apixaban and Enoxaparin for Thromboprophylaxis After Total Knee… Venous Thromboembolism (VTE) Recruiting 2026-07-13
NCT07222761 A Study to Compare Linvoseltamab Monotherapy and Linvoseltamab + Carfilzomib Combination… Relapsed and/or Refractory Multiple Myeloma (RRMM) Recruiting 2026-07-01
NCT07309432 Study of Bet v1 Antibodies Effect on Eye Allergy Symptoms in Adolescents and Adults With… Allergic Conjunctivitis Recruiting 2026-06-23
NCT07430956 Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation… Atrial Fibrillation (AF) Recruiting 2026-06-23
See all 116 active Regeneron Pharmaceuticals trials with filters →

Disease areas by active trials

Multiple Myeloma (11) · Non-Small Cell Lung Cancer (NSCLC) (10) · Lung Cancer (9) · Melanoma (6) · Obesity (5) · Ovarian Cancer (4) · Prostate Cancer (4) · Chronic Kidney Disease (4) · Atopic Dermatitis (3) · Non-Hodgkin Lymphoma (3)

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