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This After Market Study is Seeing if Dupilumab Plus Usual Standard of Care (SOC) is Better Than Usual Care Alone for Adult Participants After a Severe Chronic Obstructive Pulmonary Disease (COPD) Flare-Up Requiring Hospitalization

Study acronym: MISSION
StatusNot Yet Recruiting
PhasePhase 4
Started2026-06-30
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This study is researching a drug called dupilumab, referred to as "study drug". The study is focused on people diagnosed with COPD to determine if the study drug, in addition to standard of care treatment for COPD, might reduce the reoccurrence of a COPD exacerbation (a "flare-up") happening within the study treatment duration (around 90 days). The study is looking at another research question: • What side effects may happen from taking the study drug
Trial Details
NCT Number NCT07587658
Lead Sponsor Regeneron Pharmaceuticals
Collaborators: Sanofi
Conditions Chronic Obstructive Pulmonary Disease (COPD)
Enrollment 754 participants
Start Date 2026-06-30
Primary Completion 2028-07-30 (estimated)
Study Completion 2028-07-30 (estimated)
Updated on ClinicalTrials.gov 2026-05-14