168 active trials 107 recruiting 5 Phase 3 32 disease areas 32 changes in 30 days
16 trials changed in the last 30 days: 1 stopped, 4 with notable changes, 11 with minor changes only.
Trial terminated
Sponsor's reason: At the recommendation of the DSMB, the study was halted following an interim futility analysis, which determined that continued enrollment would not alter the study outcome.
Children's Hospital Medical Center, CincinnatiPhase 2 NCT05579639 Registry history of NCT05579639 on ClinicalTrials.gov (opens the registry)
Updated
Primary completion pushed from Mar 31, 2026 to Dec 31, 2027
Also in this update: Completion pushed from Mar 31, 2027 to Dec 31, 2028
Children's Hospital Medical Center, CincinnatiNot specified NCT04793867 Registry history of NCT04793867 on ClinicalTrials.gov (opens the registry)
Updated
Primary completion pushed from Aug 24, 2030 to Dec 24, 2031
Also in this update: Completion pushed from Aug 24, 2031 to Dec 24, 2032
Children's Hospital Medical Center, CincinnatiPhase 1/2 NCT02316379 Registry history of NCT02316379 on ClinicalTrials.gov (opens the registry)
Updated
Primary completion pushed from Sep 15, 2026 to Sep 15, 2028
Also in this update: Primary endpoint(s) modified; Completion pushed from Mar 15, 2027 to Mar 15, 2029
Children's Hospital Medical Center, CincinnatiNot applicable NCT06094504 Registry history of NCT06094504 on ClinicalTrials.gov (opens the registry)
Updated
Recruitment opened
Children's Hospital Medical Center, CincinnatiPhase 4 NCT07300956 Registry history of NCT07300956 on ClinicalTrials.gov (opens the registry)
Updated
Trial completed
Also in this update: Final enrollment: 47 participants (planned 64); Primary completion date changed from estimate of Sep 10, 2026 to May 1, 2026; and 2 more changes in the last 30 days
Children's Hospital Medical Center, CincinnatiPhase 4 NCT04259970 Registry history of NCT04259970 on ClinicalTrials.gov (opens the registry)
Updated
Trial status changed: Recruiting → Enrolling by Invitation
Children's Hospital Medical Center, CincinnatiNot applicable NCT06946355 Registry history of NCT06946355 on ClinicalTrials.gov (opens the registry)
Updated
Trial status changed: Enrolling by Invitation → Completed
Also in this update: Final enrollment: 81 participants (planned 73); Primary completion date changed from estimate of Dec 2028 to Feb 26, 2026
Children's Hospital Medical Center, CincinnatiNot specified NCT01902407 Registry history of NCT01902407 on ClinicalTrials.gov (opens the registry)
Updated
Trial completed
Also in this update: Primary completion date changed from estimate of Mar 2027 to Aug 13, 2026
Children's Hospital Medical Center, CincinnatiNot specified NCT07192887 Registry history of NCT07192887 on ClinicalTrials.gov (opens the registry)
Updated
Trial completed
Also in this update: Study completion date changed from estimate of Jun 30, 2026 to May 6, 2026
Children's Hospital Medical Center, CincinnatiPhase 2 NCT04567355 Registry history of NCT04567355 on ClinicalTrials.gov (opens the registry)
Updated
Enrollment closed, study ongoing
Also in this update: Primary completion pushed from Nov 1, 2028 to Dec 1, 2028; Final enrollment: 19 participants (planned 44)
Children's Hospital Medical Center, CincinnatiPhase 4 NCT05517655 Registry history of NCT05517655 on ClinicalTrials.gov (opens the registry)
Updated
Enrollment closed, study ongoing
Children's Hospital Medical Center, CincinnatiNot applicable NCT04715685 Registry history of NCT04715685 on ClinicalTrials.gov (opens the registry)
Updated
Primary completion pushed from Jul 2026 to Jan 2027
Children's Hospital Medical Center, CincinnatiPhase 2 NCT05538208 Registry history of NCT05538208 on ClinicalTrials.gov (opens the registry)
Updated
Completion pushed from Dec 31, 2025 to Dec 31, 2026
Children's Hospital Medical Center, CincinnatiNot applicable NCT04031716 Registry history of NCT04031716 on ClinicalTrials.gov (opens the registry)
Updated
Completion pushed from Jan 1, 2026 to Jan 1, 2027
Children's Hospital Medical Center, CincinnatiNot specified NCT04549077 Registry history of NCT04549077 on ClinicalTrials.gov (opens the registry)
Updated
Registry marked status Unknown (sponsor has not verified the record since Aug 2024); last known: Enrolling by Invitation
Children's Hospital Medical Center, CincinnatiNot applicable NCT05927194 Registry history of NCT05927194 on ClinicalTrials.gov (opens the registry)
Changed
| First posted | Trial | Phase | Status |
|---|---|---|---|
| 2026-09-29 | NCT07845942 Allogeneic Hematopoietic Cell Transplantation for Refractory Systemic Juvenile Idiopathic… | Recruiting | |
| 2026-09-16 | NCT07823010 Technical Development of Xe MRI | Phase 1/2 | Enrolling by Invitation |
| 2026-09-16 | NCT07823036 Assessing Pulmonary Changes in HSCT | Phase 1/2 | Recruiting |
| Early Phase 1 | 5 | |
| Phase 1 | 6 | |
| Phase 1/2 | 10 | |
| Phase 2 | 17 | |
| Phase 2/3 | 1 | |
| Phase 3 | 4 | |
| Phase 4 | 10 |
| NCT ID | Title | Condition | Status | Updated |
|---|---|---|---|---|
| Phase 4 | ||||
| NCT07300956 | Treating Young Children With Attention Deficit Hyperactivity Disorder | Attention-Deficit/Hyperactivity Disorder (ADHD) | Recruiting | 2026-09-14 |
| NCT04991389 | Improving Outcomes in Pediatric Obstructive Sleep Apnea With Computational Fluid Dynamics | Obstructive Sleep Apnea | Recruiting | 2026-01-07 |
| NCT04995562 | Use of Hyperpolarized 129Xe MR Lung Imaging in Infants | Lungs; Developmental Disorder | Recruiting | 2026-01-07 |
| NCT07177300 | Effectiveness of Nontraditional Hydroxyurea Algorithms: Novel and Clinical Evaluations… | Sickle Cell Anemia (HbSS) | Recruiting | 2025-09-16 |
| NCT05517655 | BEGIN Novel ImagiNG Biomarkers | Cystic Fibrosis | Active, Not Recruiting | 2026-09-22 |
| NCT07770152 | Semaglutide in Youth With Autism Spectrum Disorder | Autism Spectrum Disorder | Not Yet Recruiting | 2026-08-18 |
| NCT04219280 | Evaluating Treatment of ADHD in Children With Down Syndrome | Down Syndrome | Active, Not Recruiting | 2026-08-10 |
| NCT04128995 | Surgical or Medical Treatment | Diabetes Mellitus, Type 2 | Active, Not Recruiting | 2026-03-24 |
| NCT05659147 | Imaging Biomarkers of Pancreatic Function and Disease | Pancreatitis | Enrolling by Invitation | 2026-03-18 |
| NCT04467957 | Non-contrast Lung Perfusion Mapping Applied for New Insights in Cystic Fibrosis | Cystic Fibrosis | Active, Not Recruiting | 2026-01-28 |
| Phase 3 | ||||
| NCT04216927 | NO During CPB in Neonates to Reduce Risk of AKI | AKI | Recruiting | 2026-08-05 |
| NCT07146048 | A Non-Inferiority Trial of Stopping Penicillin in Early Rheumatic Heart Disease: GOAL-Stop | Rheumatic Heart Disease | Recruiting | 2026-06-22 |
| NCT07187206 | Safety and Efficacy of FETO in CDH Phase III | Congenital Diaphragmatic Hernia | Recruiting | 2025-09-22 |
| NCT07798232 | Penicillin to Prevent Early Rheumatic Heart Disease in School-Aged Children | Rheumatic Heart Disease in Children | Not Yet Recruiting | 2026-09-03 |
| Phase 2/3 | ||||
| NCT05660746 | Precise Infliximab Exposure and Pharmacodynamic Control | Crohn Disease | Recruiting | 2026-05-05 |
| Phase 2 | ||||
| NCT06153173 | Mirdametinib in Histiocytic Disorders | Langerhans Cell Histiocytosis (LCH) | Recruiting | 2026-09-21 |
| NCT05538208 | The Pediatric Lupus Nephritis Mycophenolate Mofetil (PLUMM) Study | Lupus Nephritis | Recruiting | 2026-09-14 |
| NCT02532452 | Third Party Viral Specific T-cells (VSTs) | Viral Infection | Recruiting | 2026-09-04 |
| NCT04230356 | Trial of Scheduled Versus Treatment Administration of Donor-Derived Viral Specific… | Allogeneic Stell Cell Transplant | Recruiting | 2026-09-04 |
| NCT06450925 | Vitamin A Supplementation in Allogeneic Stem Cell Transplantation. | Graft Vs Host Disease | Recruiting | 2026-08-24 |
| NCT07635056 | Haploidentical Donor Cytokine-Induced Memory-Like Natural Killer Cells (CIML-NK) for… | Neuroblastoma | Recruiting | 2026-08-24 |
| NCT04925375 | Abatacept for the Treatment of Common Variable Immunodeficiency With Interstitial Lung… | Interstitial Lung Disease | Recruiting | 2026-07-22 |
| NCT05501756 | Precision Alemtuzumab Dosing for Allogeneic Hematopoietic Cell Transplantation | Allogeneic Hematopoietic Cell Transplantation | Recruiting | 2026-06-12 |
| NCT05485155 | Zemaira Eosinophilic Esophagitis Pilot Study | Eosinophilic Esophagitis | Recruiting | 2025-12-17 |
| NCT02143830 | HSCT for Patients With Fanconi Anemia Using Risk-Adjusted Chemotherapy | Fanconi Anemia | Recruiting | 2025-11-12 |
Heart Disease (14) · Sickle Cell Disease (12) · Cystic Fibrosis (7) · ADHD (5) · Leukemia (5) · Obesity (5) · Crohn's Disease (4) · Depression (4) · Diabetes (4) · Migraine (4)