Asthma Ctrl SMART Trial

The primary objective is to examine the efficacy of an mHealth adherence intervention (Asthma Ctrl) on adherence to daily inhaled corticosteroids as measured by electronically monitored adherence in adolescents with asthma. The secondary objective is to compare the effectiveness of three intervention strategies: 1. asthma management app (control); 2. Asthma Ctrl; 3. Asthma Ctrl+ on adherence, lung function, and health care utilization at post-intervention and 1- and 6-month follow-up. The third objective is to explore and contrast different challenges and combinations of challenges to identify which are most impactful in determining response to the three intervention strategies.

NCT Number	NCT07512622
Lead Sponsor	Children's Hospital Medical Center, Cincinnati Collaborators: National Heart, Lung, and Blood Institute (NHLBI)
Conditions	Asthma in Children, Asthma Chronic
Enrollment	389 participants
Start Date	2026-05-30
Primary Completion	2030-01-01 (estimated)
Study Completion	2030-06-01 (estimated)
Updated on ClinicalTrials.gov	2026-05-11