Drug Pipeline

Empagliflozin Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
71
Active Studies
42
Recruiting
18
Phase 3
10
Top Sponsors
13
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-06-12 NCT06531824
EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With…
Trial sites expanded: 459 -> 475 locations
2026-06-12 NCT07599345
Emulation of the EMPEROR-Reduced Trial Using Healthcare Claims Data
Primary endpoint(s) modified
2026-06-12 NCT07599293
Emulation of the EMPEROR-Preserved Trial Using Healthcare Claims Data
Primary endpoint(s) modified
2026-06-11 NCT07064473
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin…
Trial sites expanded: 1152 -> 1155 locations
2026-06-10 NCT07214818
SGLT2 Inhibitors in Adult Primary Nephrotic Syndrome
overall status: "Active Not Recruiting" → "Recruiting"
2026-06-05 NCT06674109
SAVE-Care (Sodium Glucose Cotransporter-2 Inhibitors [SGLT2i] As Novel Gout Care) Trial
Recruitment opened
2026-06-03 NCT06531824
EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With…
Trial sites expanded: 452 -> 459 locations
2026-06-03 NCT06935370
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps…
Trial sites reduced: 639 -> 635 locations
2026-06-02 NCT07572032
Delayed Initiation of ARNI and SGLT2i in Heart Failure With Corrected Aetiology…
Recruitment opened
2026-05-23 NCT06171802
EMPagliflozin After Aortic Valve Replacement
Trial completed
2026-05-21 NCT07594145
Precision T1D Platform - New Therapies for Cardio-Renal Complications
Primary endpoint(s) modified
2026-05-14 NCT06844669
HER2HEART-US: Prevention of Cardiotoxicity in Breast Cancer Patients Receiving…
Trial terminated
2026-05-14 NCT06844669
HER2HEART-US: Prevention of Cardiotoxicity in Breast Cancer Patients Receiving…
critical why stopped: null → "Futility"
New Trial Filings, Last 30 Days
First PostedTrialPhaseStatus
2026-06-05 NCT07628556 Antidiabetic Medications and Risk of Cancer Completed
2026-05-20 NCT07599293 Emulation of the EMPEROR-Preserved Trial Using Healthcare Claims Data Active, Not Recruiting
2026-05-20 NCT07599345 Emulation of the EMPEROR-Reduced Trial Using Healthcare Claims Data Active, Not Recruiting
2026-05-18 NCT07594145 Precision T1D Platform - New Therapies for Cardio-Renal Complications Phase 2 Not Yet Recruiting
2026-05-15 NCT07591077 SGLT2 Adjunct in T1D Phase 2/3 Completed
Active Studies by Phase
Phase 4
16
Phase 3
15
Phase 2/3
3
Phase 2
17
Phase 1/2
3
Phase 1
2
Early Phase 1
5
Not specified
10
Active Trials — top 25 of 71
NCT IDTitleConditionStatus
Phase 4
NCT05164263 Real World Safety & Efficacy Experience of Empagliflozin With or Without Metformin in… Type II Diabetes Mellitus Recruiting
NCT06625073 Randomized Trial of SGLT2i in Heart Transplant Recipients Heart Transplant Recruiting
NCT06055452 Effects of SGLT2 Inhibitors in Pre-heart Failure Populations With Hypertension Pre-Heart Failure Recruiting
NCT06013865 Empagliflozin Treatment in Kidney Transplant Recipients Kidney Transplant Recruiting
NCT06613854 Effect of Early Combination Antihyperglycemic Treatment on Metabolic Control in… Type 2 Diabetes Mellitus (T2DM) Recruiting
NCT05671991 Effect of Empagliflozin on Peritoneal and Kidney Function in End Stage Renal Disease End Stage Renal Disease on Dialysis Recruiting
NCT07572032 Delayed Initiation of ARNI and SGLT2i in Heart Failure With Corrected Aetiology… Heart Failure Due to Coronary Artery Disease Recruiting
NCT06674109 SAVE-Care (Sodium Glucose Cotransporter-2 Inhibitors [SGLT2i] As Novel Gout Care) Trial Gout and Hyperuricemia Recruiting
NCT07325435 Beta Cell Function in Type 2 Diabetes: Differential Effects of SGLT2 Inhibitors and… Type 2 Diabetes (T2DM) Active, Not Recruiting
NCT05426525 Use of Empagliflozin to Treat Prediabetes PreDiabetes Active, Not Recruiting
NCT07074418 Effect of Empagliflozin in Patients With eGFR Between 10 and 20 ml/Min/1.73m2 Chronic Kidney Diseases Not Yet Recruiting
NCT07365358 Evaluate the Efficacy and Safety of Empagliflozin or Glimepiride Combination Therapy in… Diabete Type 2 Not Yet Recruiting
NCT05147090 Effects of Empagliflozin on Fibrosis and Cirrhosis in Chronic Hepatitis B Patients Chronic Hepatitis b Active, Not Recruiting
NCT06851962 Impact of Pharmacogenetic-Guided Treatment on Type 2 Diabetes. Diabetes Mellitus Type 2 Active, Not Recruiting
NCT07547878 Rapid and Simultaneous Initiation of Four Guideline-Directed CKD Therapies (RAPID-CKD) Chronic Kidney Disease Not Yet Recruiting
NCT07228195 SGLT2i Therapy in Islet Transplantation (SIT) Partial Islet Function Not Yet Recruiting
Phase 3
NCT05669742 Empagliflozin Addition in Modulating Metabolic Disturbances Associated With Olanzapine in… Sodium-glucose Transport Protein Two Inhibitor (SGLT2),Metabolic Deficits Caused by Antipsychotics Recruiting
NCT05392764 Early Treatment With a Sodium-glucose Co-transporter 2 Inhibitor in High-risk Patients… Acute Heart Failure Recruiting
NCT06217302 Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and… Diabetic Nephropathies Recruiting
NCT07038356 Effects of Continued Administration of Empagliflozin in Patients With Heart Failure on… Acute Decompensated Heart Failure (ADHF) Recruiting
NCT04381936 Randomised Evaluation of COVID-19 Therapy Pneumonia Recruiting
NCT05715814 meChANisms and sAfety of SGLT2 Inhibition in peRitoneal dialYsis Peritoneal Dialysis Complication Recruiting
NCT06481891 A Study to Evaluate the Efficacy and Safety of Sotagliflozin in Symptomatic Obstructive… Obstructive Cardiomyopathy, Hypertrophic Recruiting
NCT06424288 A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With… Heart Failure Recruiting
NCT06935370 A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps… Heart Failure Recruiting
Sponsors Running Empagliflozin Trials
Disease Areas
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