Sponsor Pipeline

Roche / Genentech Clinical Trial Pipeline

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
256
Active Trials
111
Recruiting
90
Phase 3
10
Disease Areas
82
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-06-12 NCT03194893
A Rollover Study of Alectinib in Patients With Anaplastic Lymphoma Kinase (ALK)-Positive…
Trial completed
2026-06-12 NCT03194893
A Rollover Study of Alectinib in Patients With Anaplastic Lymphoma Kinase (ALK)-Positive…
Enrollment reduced: 200 -> 50 participants
2026-06-12 NCT03194893
A Rollover Study of Alectinib in Patients With Anaplastic Lymphoma Kinase (ALK)-Positive…
date change Primary completion moved earlier: 2026-05-30 -> 2025-09-18
2026-06-12 NCT03194893
A Rollover Study of Alectinib in Patients With Anaplastic Lymphoma Kinase (ALK)-Positive…
date change Completion moved earlier: 2026-05-30 -> 2025-09-18
2026-06-12 NCT07567846
A Study Evaluating the Safety, Pharmacokinetics, and Preliminary Activity of GDC-1261 in…
Recruitment opened
2026-06-12 NCT05115110
A Study to Investigate the Safety and Efficacy of RO7204239 in Combination With Risdiplam…
date change Primary completion moved earlier: 2029-02-27 -> 2026-10-28
2026-06-12 NCT05115110
A Study to Investigate the Safety and Efficacy of RO7204239 in Combination With Risdiplam…
date change Completion moved earlier: 2029-02-27 -> 2026-10-28
2026-06-11 NCT07413939
RO7771950 Versus Tucatinib in Combination With Trastuzumab and Capecitabine in People…
Trial sites expanded: 4 -> 55 locations
2026-06-10 NCT06793215
A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus…
Trial sites expanded: 240 -> 251 locations
2026-06-10 NCT07368998
To Study the Effect of Inavolisib in Combination With Fulvestrant in Participants With…
Trial sites expanded: 19 -> 26 locations
2026-06-10 NCT06176352
A Study to Evaluate the Efficacy and Safety of Faricimab in Patients With Choroidal…
Trial completed
2026-06-10 NCT07448038
A Study to Evaluate the Efficacy, Safety, Pharmacodynamics (PD), and Pharmacokinetics…
Trial sites expanded: 6 -> 11 locations
2026-06-09 NCT06534983
A Study to Evaluate the Efficacy and Safety of Autogene Cevumeran With Nivolumab Versus…
Primary endpoint(s) modified
2026-06-09 NCT06534983
A Study to Evaluate the Efficacy and Safety of Autogene Cevumeran With Nivolumab Versus…
Enrollment reduced: 362 -> 62 participants
2026-06-09 NCT05271409
A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of…
overall status: "Recruiting" → "Active Not Recruiting"
2026-06-09 NCT05271409
A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of…
Trial sites reduced: 82 -> 54 locations
2026-06-09 NCT06819891
A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart…
Trial sites expanded: 173 -> 178 locations
2026-06-09 NCT06693908
A Study to Evaluate the Activity, and Safety of Vixarelimab in Participants With Moderate…
date change Primary completion pushed: 2026-06-09 -> 2026-07-09
2026-06-09 NCT05503264
A Study to Evaluate the Efficacy, Safety, Pharmacokinetics (PK), and Pharmacodynamics…
Enrollment reduced: 152 -> 120 participants
2026-06-09 NCT05503264
A Study to Evaluate the Efficacy, Safety, Pharmacokinetics (PK), and Pharmacodynamics…
date change Completion moved earlier: 2029-12-14 -> 2028-12-14
Showing 20 of 82 changes detected in the last 30 days.
New Trial Filings, Last 30 Days
First PostedTrialPhaseStatus
2026-06-05 NCT07629583 To Evaluate the Effects of Cevostamab in Participants With Systemic Lupus Erythematosus… Phase 1 Not Yet Recruiting
2026-06-04 NCT07626515 A Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Enicepatide in… Phase 1 Not Yet Recruiting
2026-06-02 NCT07620392 An Extension Study to Assess Long-Term Safety and Efficacy of Afimkibart in Participants… Phase 2 Not Yet Recruiting
2026-06-01 NCT07617337 AQUA07 in Patients With ALK-Positive Non-Small Cell Lung Cancer Phase 1 Not Yet Recruiting
2026-05-27 NCT07609719 A Study of Ocrelizumab Administered Subcutaneously in Participants With Multiple… Phase 4 Not Yet Recruiting
2026-05-20 NCT07598396 A Study to Evaluate Mosunetuzumab in Participants With Systemic Lupus Erythematosus With… Phase 2 Recruiting
2026-05-15 NCT07589686 A Dose-Finding Study of Petrelintide With Enicepatide (RO7795068) in Adults With Obesity… Phase 2 Not Yet Recruiting
2026-05-14 NCT07588100 A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of RO7663498… Phase 1 Not Yet Recruiting
Active Trials by Phase
Phase 4
11
Phase 3
86
Phase 2/3
4
Phase 2
52
Phase 1/2
27
Phase 1
52
Not specified
24
Active Trials — top 25 of 256
NCT IDTitleConditionStatus
Phase 4
NCT05861986 A Study Evaluating the Effectiveness and Safety of Risdiplam Administered as an Early… Muscular Atrophy, Spinal Recruiting
NCT04853251 A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related… Neovascular Age-related Macular Degeneration Recruiting
NCT07483450 A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of… Relapsing Multiple Sclerosis Recruiting
NCT06274515 A Study to Investigate Mechanisms of Resistance to Breast Cancer Therapies Breast Cancer Recruiting
NCT05861999 A Study Evaluating the Effectiveness and Safety of Risdiplam Administered in Pediatric… Muscular Atrophy, Spinal Recruiting
NCT05232929 Long-term Follow-up Study of Risdiplam in Participants With Spinal Muscular Atrophy (SMA) Spinal Muscular Atrophy Active, Not Recruiting
NCT05181618 A Study to Evaluate Overall Health, Physical Activity, and Joint Outcomes in Participants… Severe Hemophilia A Active, Not Recruiting
NCT06795048 A Study to Determine the Efficacy, Safety, and Durability of Faricimab in Participants… Neovascular Age-related Macular Degeneration (nAMD) Active, Not Recruiting
NCT07025811 A Study to Explore Signs, Symptoms, and Biomarkers in Dry Eye Disease Participants… Dry Eye Disease Active, Not Recruiting
NCT05224102 A Study to Investigate Faricimab Treatment Response in Treatment-Naive, Underrepresented… Diabetic Macular Edema Active, Not Recruiting
NCT07609719 A Study of Ocrelizumab Administered Subcutaneously in Participants With Multiple… Multiple Sclerosis Not Yet Recruiting
Phase 3
NCT06675955 An Extension Study to Assess Impact of Multiple Sclerosis (MS) on Physical Function and… Multiple Sclerosis Recruiting
NCT06094010 A Surveillance Study of Susceptibility to Baloxavir Marboxil in Pediatric Participants… Influenza Recruiting
NCT05797610 A Study to Evaluate the Efficacy and Safety of Sefaxersen (RO7434656) in Participants… Primary IgA Nephropathy Recruiting
NCT05862285 A Rollover Study for Participants Previously Enrolled in a Genentech and/or F. Hoffman-La… Cancer Recruiting
NCT07298421 A Study to Assess the Pharmacokinetics, Effectiveness and Safety of Afimkibart for… Moderately to Severely Active Crohns Disease Recruiting
NCT06998524 A Study to Assess the Efficacy and Safety of Emicizumab in Participants With Type 3 Von… Von Willebrand Disease, Type 3 Recruiting
NCT07158242 A Study to Evaluate the Pharmacokinetics, Safety and Efficacy of Afimkibart (RO7790121)… Moderately to Severely Active Ulcerative Colitis Recruiting
NCT06847542 A Study of 36-Week Refill Exchanges of Port Delivery System (PDS) With Ranibizumab in nAMD Neovascular Age-related Macular Degeneration Recruiting
NCT07351058 A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With… Obesity or Overweight Recruiting
NCT07555938 Cevostamab in Combination With Pomalidomide and Dexamethasone Versus Standard of Care in… Multiple Myeloma Recruiting
NCT05894239 A Study to Evaluate the Efficacy and Safety of Inavolisib in Combination With Phesgo… Metastatic Breast Cancer Recruiting
NCT07351045 A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With… Obesity or Overweight Recruiting
NCT05878769 A Study to Evaluate the Long-Term Safety of Astegolimab in Participants With Chronic… Chronic Obstructive Pulmonary Disease Recruiting
NCT06084936 A Study to Evaluate Glofitamab as a Single Agent vs. Investigator's Choice in… Lymphoma Recruiting
View all 256 active Roche / Genentech trials with filters →
Disease Areas
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