| Detected | Trial | Change |
|---|---|---|
| 2026-08-15 | NCT07332481 A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or… · EMD Serono Research & Development Institute, Inc. |
Trial sites expanded: 13 -> 18 locations |
| 2026-08-14 | NCT05352919 An Extension Study to Learn More About the Long-Term Safety of Litifilimab (BIIB059)… · Biogen |
Trial sites expanded: 197 -> 203 locations |
| 2026-08-13 | NCT07203157 HEAL-SLE: Holistic Energy for Alleviating Lupus Symptoms · NYU Langone Health |
overall status: Not Yet Recruiting → Active, Not Recruiting |
| 2026-08-13 | NCT07203157 HEAL-SLE: Holistic Energy for Alleviating Lupus Symptoms · NYU Langone Health |
date change Primary completion pushed: 2026-03-31 -> 2026-10 |
| 2026-08-13 | NCT07203157 HEAL-SLE: Holistic Energy for Alleviating Lupus Symptoms · NYU Langone Health |
date change Completion pushed: 2026-09-20 -> 2026-10-31 |
| 2026-08-13 | NCT07694336 A Study of Quinacrine in Participants With Cutaneous Lupus Erythematosus · Victoria Werth |
Recruitment opened |
| 2026-08-12 | NCT06144710 SG301-SC Injection Safety Study in Subjects With Systemic Lupus Erythematosus · Hangzhou Sumgen Biotech Co., Ltd. |
Trial completed |
| 2026-08-12 | NCT06144710 SG301-SC Injection Safety Study in Subjects With Systemic Lupus Erythematosus · Hangzhou Sumgen Biotech Co., Ltd. |
date change Completion moved earlier: 2026-10-24 -> 2026-01-07 |
| 2026-08-11 | NCT07483346 IASO-782 in Systemic Lupus Erythematosus · Shanghai IASO Biotechnology Co., Ltd |
Recruitment opened |
| 2026-08-11 | NCT07483346 IASO-782 in Systemic Lupus Erythematosus · Shanghai IASO Biotechnology Co., Ltd |
Trial sites expanded: 0 -> 4 locations |
| 2026-08-11 | NCT06977724 A Study to Assess Adverse Events, How the Drug Moves Through the Body and Effectiveness… · AbbVie |
Trial arms changed: 6 -> 8 |
| 2026-08-11 | NCT06977724 A Study to Assess Adverse Events, How the Drug Moves Through the Body and Effectiveness… · AbbVie |
Trial sites expanded: 7 -> 11 locations |
| 2026-08-09 | NCT06677801 Immune Cell Subsets in SLE Patients Treated with Telitacicept · Second Affiliated Hospital, School of Medicine, Zhejiang University |
Sponsor changed: Second Affiliated Hospital, School of Medicine, Zhejiang University -> Second Affiliated Hospital, Zhejiang University, School of Medicine |
| 2026-08-09 | NCT06614270 Anti-CD19 IL-10/IL15 CAR-NK Cells in Refractory/Relapsed Autoimmune Diseases · Second Affiliated Hospital, School of Medicine, Zhejiang University |
Sponsor changed: Second Affiliated Hospital, School of Medicine, Zhejiang University -> Second Affiliated Hospital, Zhejiang University, School of Medicine |
| 2026-08-09 | NCT05916781 Effectiveness of Mycophenolate Mofetil Combined With Tacrolimus for Steroid Tapering in… · Chinese SLE Treatment And Research Group |
overall status: Recruiting → Unknown |
| 2026-08-08 | NCT04976322 A Study to Evaluate the Safety and Tolerability of Dapirolizumab Pegol in Study… · UCB Biopharma SRL |
Trial sites expanded: 118 -> 121 locations |
| 2026-08-08 | NCT07629583 To Evaluate the Effects of Cevostamab in Participants With Systemic Lupus Erythematosus… · Genentech, Inc. |
Recruitment opened |
| 2026-08-08 | NCT06617325 A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants… · UCB Biopharma SRL |
Trial sites expanded: 233 -> 236 locations |
| 2026-08-07 | NCT05039840 Efficacy and Safety of Frexalimab (SAR441344) in the Treatment of Systemic Lupus… · Sanofi |
date change Primary completion pushed: 2026-07-10 -> 2026-09-03 |
| 2026-08-07 | NCT05039840 Efficacy and Safety of Frexalimab (SAR441344) in the Treatment of Systemic Lupus… · Sanofi |
date change Completion pushed: 2026-10-02 -> 2026-11-24 |
| First Posted | Trial | Sponsor | Phase |
|---|---|---|---|
| 2026-08-12 | NCT07760155 A Phase 2 Study on the Safety and Efficacy of the Anti-BAFF-R Monoclonal Antibody… | Shanghai Escugen Biotechnology Co., Ltd NEW | Phase 2 |
| 2026-08-12 | NCT07760480 Assessing Residual Inflammation and Macrophage Presence in Lupus Nephritis After 3 Months… | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) NEW | Phase 4 |
| 2026-07-28 | NCT07732309 A Study of ATG-201 in Adult Participants With Autoimmune Diseases | Antengene Biologics Limited NEW | Phase 1 |
| 2026-07-22 | NCT07719140 Childhood-onset Lupus Nephritis Initial Glucocorticoid-dose Harmonization Trial (LIGHT… | Peking Union Medical College Hospital NEW | Phase 4 |
| 2026-07-22 | NCT07720310 Anti-CD19 CAR-T Cell Therapy for Patients With Refractory Systemic Lupus Erythematosus | N.N. Alexandrov National Cancer Centre NEW | |
| 2026-07-21 | NCT07716462 Home-Based High-Intensity Interval Training in Systemic Lupus Erythematosus | University of Alabama at Birmingham NEW | |
| 2026-07-20 | NCT07713940 Effect of Anti-inflammatory Diet in Systemic Lupus Erythematous | University of California, San Diego NEW | |
| 2026-07-16 | NCT07706998 Application of the AI Platform iLN Based on DeepSeek in the Teaching of Lupus Nephritis | Nanjing University NEW | |
| 2026-07-14 | NCT07700940 The Efficacy of Empagliflozin on Kidney Functions in Lupus Nephritis Population | Ahmed Yehia Ismail NEW | Phase 4 |
| 2026-07-09 | NCT07694336 A Study of Quinacrine in Participants With Cutaneous Lupus Erythematosus | Victoria Werth NEW | Phase 2 |
| NCT ID | Title | Sponsor | Status |
|---|---|---|---|
| Phase 4 | |||
| NCT05207358 | Minimizing Glucocorticoid Administration in Patients With Proliferative Lupus Nephritis | Institutul Clinic Fundeni | Recruiting |
| NCT07225387 | Safety and Efficacy of Combination Belimumab and Voclosporin in the Treatment of… | NephroNet, Inc. | Recruiting |
| NCT05559671 | Safety of the Herpes Zoster Subunit Vaccine in Lupus | NYU Langone Health | Recruiting |
| NCT07077486 | Effects of Telitacicept vs Cyclophosphamide on Lupus Related Interstitial Lung Disease | Tongji Hospital | Recruiting |
| NCT06875960 | A Study to Continue the Administration of Deucravacitinib in Participants With Systemic… | Bristol-Myers Squibb | Recruiting |
| NCT07323524 | Dapagliflozin in Active Lupus Nephritis | Brigham and Women's Hospital | Recruiting |
| NCT07611747 | Carotid Ultrasound-Based Strategy for Primary Prevention of Cardiovascular Events in… | Instituto de Investigación Marqués de Valdecilla | Recruiting |
| NCT06411249 | A Study Describing the Efficacy and Safety of Belimumab Administered in Adult… | GlaxoSmithKline | Recruiting |
| NCT03543839 | Trial of Belimumab in Early Lupus | Northwell Health | Recruiting |
| NCT07700940 | The Efficacy of Empagliflozin on Kidney Functions in Lupus Nephritis Population | Ahmed Yehia Ismail | Recruiting |
| NCT07087912 | Safety and Immunogenicity of the Live Attenuated Tetravalent Butantan-Dengue Vaccine in… | University of Sao Paulo General Hospital | Recruiting |
| NCT06594068 | Prospective Registry Investigating Maternal, Infant, and Lactation Outcomes in… | AstraZeneca | Recruiting |
| NCT07719140 | Childhood-onset Lupus Nephritis Initial Glucocorticoid-dose Harmonization Trial (LIGHT… | Peking Union Medical College Hospital | Recruiting |
| NCT07611214 | PRESERVE: LUPKYNIS in Combination With Belimumab, Obinutuzumab or Anifrolumab in Patients… | Aurinia Pharmaceuticals Inc. | Recruiting |
| NCT07760480 | Assessing Residual Inflammation and Macrophage Presence in Lupus Nephritis After 3 Months… | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | Recruiting |
| NCT06677801 | Immune Cell Subsets in SLE Patients Treated with Telitacicept | Second Affiliated Hospital, School of Medicine, Zhejiang University | Active, Not Recruiting |
| NCT06763783 | Vaccination Against Herpes Zoster in Patients With Inflammatory Rheumatic Diseases | Region Skane | Enrolling by Invitation |
| NCT07035834 | SGLT-2 Inhibitors on Albuminuria in Chronic Kidney Disease Patients With Lupus Nephritis… | Federico II University | Not Yet Recruiting |
| NCT05879419 | Recombinant Herpes Zoster Vaccine in Patients With Autoimmune Rheumatic Diseases | University of Sao Paulo General Hospital | Active, Not Recruiting |
| NCT07381465 | Efficacy and Safety of IL-1 Inhibitors in Mild to Moderate Systemic Lupus Erythematosus | Chinese SLE Treatment And Research Group | Active, Not Recruiting |
| Phase 3 | |||
| NCT06406205 | A Study of QLG1074 Combined With Background Therapy in Subjects With Active Lupus… | Qilu Pharmaceutical Co., Ltd. | Recruiting |
| NCT06904729 | Chimeric Antigen Receptors T Cells for Refractory/Recurrent Lupus Nephritis in Children | Guangzhou Women and Children's Medical Center | Recruiting |
| NCT04702256 | Induction Therapy for Lupus Nephritis With no Added Oral Steroids: A Trial Comparing Oral… | Assistance Publique - Hôpitaux de Paris | Recruiting |
| NCT07405970 | A Phase 3 Clinical Study of MIL62 in Systemic Lupus Erythematosus | Beijing Mabworks Biotech Co., Ltd. | Recruiting |
| NCT06133972 | Phase 3 Extension Study to Evaluate Long-term Safety of Ianalumab in Participants With… | Novartis Pharmaceuticals | Recruiting |