Disease landscape

Hemophilia clinical trials

Get alerts when Hemophilia trials change

177 active trials 90 recruiting 40 Phase 3 87 sponsors 25 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-08-28

What changed in the last 30 days

2026-08-14
Trial terminated
Trial terminated: Sangamo declared Chapter 11 Bankruptcy on 23Jun2026 and terminated the study on 21Jul2026.
Primary completion moved earlier: 2030-01-01 → 2026-06-17
Completion moved earlier: 2030-01-01 → 2026-06-17
NCT04628871 Long Term Follow-up (LTFU) of Subjects Who Received SB-318, SB-913, or SB-FIX · Sangamo Therapeutics
2026-08-27
Primary completion pushed: 2027-05-31 → 2028-05-31
Trial status changed: Recruiting → Not Yet Recruiting
Completion pushed: 2028-06-01 → 2028-12-31
NCT03961243 Lentiviral FIX Gene Therapy · Shenzhen Geno-Immune Medical Institute · Phase 1
2026-08-08
Primary completion pushed: 2026-05-21 → 2026-08-21
Completion pushed: 2026-05-21 → 2026-08-21
NCT05568459 A Trial That Evaluates Disease Characteristics in Hemophilia B Adult Male Participants… · Regeneron Pharmaceuticals
2026-08-18
Primary completion pushed: 2027-09 → 2028-02
Primary endpoint(s) modified
Completion pushed: 2027-09 → 2028-02
NCT07719647 Ultrasound Assessment of Joint Health in Patients With Mild Hemophilia (Factor Levels… · Assistance Publique - Hôpitaux de Paris
2026-08-13
Enrollment closed, study ongoing
NCT06922045 Phase III Clinical Trial of STSP-0601 for Injection in Hemophilia Patients · Jiangsu BioJeTay Biotechnology Co., Ltd. · Phase 3
2026-08-12
Trial completed
Primary completion moved earlier: 2029-05-29 → 2026-07-23
Completion moved earlier: 2029-10-25 → 2026-07-23
NCT03307980 Long-term Safety and Efficacy Study and Dose-Escalation Substudy of PF 06838435 in… · Pfizer · Phase 2
2026-08-04
Completed without a posted recruiting period
NCT07516730 Central Pain Mechanisms and Clinical and Psychological Factors Associated With Pain… · Investigación en Hemofilia y Fisioterapia
2026-08-11
Trial sites expanded: 34 → 64 locations
NCT05611801 A Clinical Trial of Study Medicine (Marstacimab) in Pediatric Patients With Hemophilia A… · Pfizer · Phase 3
2026-08-07
Trial sites expanded: 12 → 30 locations
NCT07416604 A Clinical Study to Evaluate the Effects of NXT007 Compared to Emicizumab Prophylaxis in… · Hoffmann-La Roche · Phase 3
2026-08-07
Trial sites expanded: 2 → 19 locations
NCT07416526 A Clinical Study to Evaluate the Effects of NXT007 Compared to Factor VIII Prophylaxis in… · Hoffmann-La Roche · Phase 3
2026-08-18
Trial sites expanded: 71 → 76 locations
NCT04398628 ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders · American Thrombosis and Hemostasis Network
2026-08-08
Primary completion moved earlier: 2029-10-31 → 2028-05-31
Completion moved earlier: 2029-10-31 → 2028-05-31
NCT06461533 A Survey of Susoctocog Alfa (Genetical Recombination) in Participants With Acquired… · Takeda
2026-08-22
Primary completion moved earlier: 2027-03 → 2026-11
Completion moved earlier: 2027-07 → 2026-12
NCT04278404 Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered… · Duke University

New sponsor entrants, last 90 days sponsors with their first trial in this area

First postedTrialSponsorPhase
2026-08-26 NCT07787091 A First-in Human Study of ARD001 in Healthy Volunteers and People With Hemophilia A Arditus Pte Ltd new Phase 1/2
2026-07-30 NCT07736976 Comparison of 30-Second Sit-to-Stand Test Performance Between Individuals With Hemophilia… Bahçeşehir University new
2026-07-08 NCT07691437 Effect of Non-Surgical Periodontal Treatment on Oral Health in Hemophilia Patients Karadeniz Technical University new
2026-07-06 NCT07682519 Multimodal Telerehabilitation Versus Face-to-Face Care for Adults With Hemophilia and… University of Chile new
2026-07-02 NCT07681089 A Phase 2 Study of Foscenvivint in Liver Cirrhosis Patients Caused by HIV/HCV… Kiminori Kimura, MD new Phase 2
2026-06-23 NCT07663903 Study of Recombinant Human Coagulation Factor VIII-Fc Fusion Protein (FRSW107) On-Demand… Hangzhou Gensciences Biopharmaceutical Co., Ltd. new Phase 3
2026-06-12 NCT07644832 An Open-label, Multicenter Phase I/II Clinical Trial to Evaluate the Safety… Shanghai RAAS Blood Products Co., Ltd. new Phase 1/2

Active trials by phase

Early Phase 1
2
Phase 1
9
Phase 1/2
13
Phase 2
2
Phase 2/3
5
Phase 3
35
Phase 4
14
Not charted: 97 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 177

NCT IDTitleSponsorStatusUpdated
Phase 4
NCT06940830 Long-term Study Evaluating Joint Health in People With Haemophilia A Receiving Real-world… Swedish Orphan Biovitrum Recruiting 2026-06-30
NCT06145373 A Study to Test a Medicine (Fitusiran) for Preventing Bleeds in People With Severe… Sanofi Recruiting 2026-06-02
NCT05935358 Nuwiq for Perioperative Management Of Patients With Haemophilia A on Emicizumab Regular… Octapharma Recruiting 2026-05-12
NCT05936580 Nuwiq Dosing and Outcomes In the ManagEment of Women/Girls With Haemophilia A Needing… Octapharma Recruiting 2026-05-12
NCT07406139 PCC Treatment for Hemophilia Patients With Inhibitor（2022PCC-A） Institute of Hematology & Blood Diseases Hospital, China Recruiting 2026-02-12
NCT04647227 SEVENFACT® for Bleeding Events in Hemophilia With Inhibitors American Thrombosis and Hemostasis Network Recruiting 2026-01-12
NCT05849740 An Exploratory Study of Cluster of Differentiation 38 (CD38) Monoclonal Antibody Combined… Institute of Hematology & Blood Diseases Hospital, China Recruiting 2025-08-05
NCT06864975 Assessing Different FVIII Doses and Frequencies in Immune Tolerance Induction (ITI) with… Runhui WU Recruiting 2025-03-07
NCT05888870 ITI Using SCT800 Alone or Combining Daratumumab in Hemophilia A Adolescents and Adults… Institute of Hematology & Blood Diseases Hospital, China Recruiting 2025-02-24
NCT06320626 Pharmacokinetic-guided Dosing of Emicizumab Kathelijn Fischer Recruiting 2024-03-20
NCT05181618 A Study to Evaluate Overall Health, Physical Activity, and Joint Outcomes in Participants… Hoffmann-La Roche Active, Not Recruiting 2026-07-27
NCT07158606 Understanding Treatment Outcomes and Immunologic Mechanisms in Altuviiio Immune Tolerance… Versiti Blood Health Not Yet Recruiting 2026-07-27
NCT06752850 A Study to Investigate the Course of Synovial Hypertrophy in Patients With Haemophilia A… Swedish Orphan Biovitrum Active, Not Recruiting 2026-04-30
NCT04205175 A Study to Evaluate the Safest Dose Range for FEIBA in Hemophilia A Patients With… Children's Hospital Los Angeles Active, Not Recruiting 2022-03-09
Phase 3
NCT06003387 Efficacy and Safety of CSL222 (Etranacogene Dezaparvovec) Gene Therapy in Adults With… CSL Behring Recruiting 2026-08-27
NCT04563520 SAFE Study: Safety of aPCC Following Emicizumab Prophylaxis Emory University Recruiting 2026-08-21
NCT07285460 A Study to Investigate the Efficacy and Safety of Fitusiran Prophylaxis in Male… Sanofi Recruiting 2026-08-17
NCT05611801 A Clinical Trial of Study Medicine (Marstacimab) in Pediatric Patients With Hemophilia A… Pfizer Recruiting 2026-08-10
NCT07416526 A Clinical Study to Evaluate the Effects of NXT007 Compared to Factor VIII Prophylaxis in… Hoffmann-La Roche Recruiting 2026-08-06
NCT07416604 A Clinical Study to Evaluate the Effects of NXT007 Compared to Emicizumab Prophylaxis in… Hoffmann-La Roche Recruiting 2026-08-06
NCT07080905 Phase 3, Open-label, Single-dose Study of CSL222 in Adolescent Male Subjects (≥ 12 to <… CSL Behring Recruiting 2026-08-05
NCT07684898 Study of Recombinant Human Coagulation Factor VIII-Fc Fusion Protein (FRSW107) as… Hangzhou Gensciences Biopharmaceutical Co., Ltd. Recruiting 2026-07-06
NCT05145127 Open-Label Extension Study of Marstacimab in Hemophilia Participants With or Without… Pfizer Recruiting 2026-07-01
NCT05685238 A Research Study Looking at Long-term Treatment With Mim8 in People With Haemophilia A Novo Nordisk A/S Recruiting 2026-06-30
NCT06716814 Study to Provide Continued Access to Treatment for Patients Completing a Previous Trial… Swedish Orphan Biovitrum Recruiting 2026-06-26
See all 177 active Hemophilia trials with filters →

Top sponsors by active trials in this area

Institute of Hematology & Blood Diseases Hospital, China (14) · Novo Nordisk A/S (14) · Bayer (7) · Pfizer (7) · CSL Behring (6) · Hoffmann-La Roche (6) · Investigación en Hemofilia y Fisioterapia (5) · Sanofi (5) · Hangzhou Gensciences Biopharmaceutical Co., Ltd. (4) · Suzhou Alphamab Co., Ltd. (4)

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