Disease landscape

Non-Hodgkin Lymphoma clinical trials

Get alerts when Non-Hodgkin Lymphoma trials change

447 active trials 257 recruiting 13 Phase 3 252 sponsors 63 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-08-28

What changed in the last 30 days showing 40 of 63 changes on 20 trials

2026-07-30
Trial terminated
Trial terminated: Sponsor decided to discontinue development of the compound
Enrollment reduced: 24 → 2 participants
Primary completion moved earlier: 2027-07-31 → 2026-04-28
Completion moved earlier: 2029-12-31 → 2026-04-28
NCT06622226 A Study of ONO-7018 in Patients With Relapsed or Refractory Non-Hodgkin Lymphoma · Ono Pharmaceutical Co., Ltd. · Phase 1
2026-08-14
Recruitment suspended
Recruitment suspended: Accrual Goal Met
NCT04930653 Extracorporeal Photopheresis and Mogamulizumab for the Treatment of Erythrodermic… · City of Hope Medical Center · Phase 2
2026-07-30
Primary completion pushed: 2026-05 → 2029-08
Completion pushed: 2026-06 → 2029-08
NCT05645107 A Study to Evaluate Efficacy, Safety, and PK of XEMBIFY®+Standard Medical Treatment (SMT)… · Grifols Therapeutics LLC · Phase 3
2026-08-14
Primary completion pushed: 2027-11-24 → 2028-04-21
NCT06526793 Surovatamig (AZD0486) as Monotherapy in Participants With Relapsed/Refractory (R/R)… · AstraZeneca · Phase 2
2026-08-28
Primary completion pushed: 2026-07 → 2027-07
Completion pushed: 2026-07 → 2027-07
NCT04464200 19(T2)28z1xx Chimeric Antigen Receptor (CAR) T Cells in People With B-Cell Cancers · Memorial Sloan Kettering Cancer Center · Phase 1
2026-08-28
Primary completion pushed: 2026-07 → 2026-11
Completion pushed: 2026-07 → 2026-11
NCT06383338 A Study Investigating the Change in Metabolism Phenotype in Paediatric, Adolescent &… · Murdoch Childrens Research Institute · Phase 1
2026-07-30
Primary completion pushed: 2026-09 → 2027-09
Primary endpoint(s) modified
NCT05365659 IKS03 in Patients With Advanced B Cell Non-Hodgkin Lymphomas · Iksuda Therapeutics Ltd. · Phase 1
2026-08-06
Primary completion pushed: 2039-12-01 → 2041-12-01
Primary endpoint(s) modified
Trial sites expanded: 5 → 11 locations
Completion pushed: 2039-12-01 → 2041-12-01
NCT06116110 Lentiviral Gene Therapy (Zamtocabtagene Autoleucel) LTFU · Miltenyi Biomedicine GmbH
2026-08-08
Primary completion pushed: 2026-06-30 → 2027-06-30
Completion pushed: 2028-06-30 → 2029-06-30
NCT06486051 A Study of Atlacabtagene Autoleucel CAR T-cells for Adults With Relapsed Large B-cell… · Malaghan Institute of Medical Research · Phase 2
2026-08-07
Primary completion pushed: 2026-08-31 → 2028-08-31
Completion pushed: 2026-08-31 → 2028-08-31
NCT02861417 Busulfan, Fludarabine Phosphate, and Post-Transplant Cyclophosphamide in Treating… · M.D. Anderson Cancer Center · Phase 2
2026-08-22
Primary endpoint(s) modified
NCT05006716 A Dose-Escalation and Expansion Study of Tacabrutideg (BGB-16673) in Participants With… · BeOne Medicines · Phase 1/2
2026-08-07
Primary completion pushed: 2026-07 → 2028-07
Completion pushed: 2027-07 → 2030-07
NCT05990465 LV20.19 CAR T-Cells in Combination With Pirtobrutinib for Relapsed, Refractory B-cell… · Medical College of Wisconsin · Phase 1
2026-08-15
Primary completion pushed: 2026-06-30 → 2027-05-25
Completion pushed: 2026-06-30 → 2027-05-25
NCT04537871 Cardiovascular Reserve Evaluation in Survivors of Transplant, CREST Study · City of Hope Medical Center
2026-08-12
Primary endpoint(s) modified
Completion pushed: 2025-11 → 2029-06
NCT03505762 Tailored Prednisone Reduction in Preventing Hyperglycemia in Participants With B-Cell… · Wake Forest University Health Sciences · Phase 2
2026-07-31
Primary endpoint(s) modified
Enrollment reduced: 250 → 118 participants
Enrollment closed, study ongoing
NCT07259304 Social Health, Activity Behaviors, and Quality of Life Among Young Adult Cancer Survivors · University of Southern California
2026-08-22
Recruitment opened
Trial sites expanded: 17 → 22 locations
NCT07192471 A First-in-Human Study of KK2223 in Participants With Relapsed or Refractory T Cell… · Kyowa Kirin, Inc. · Phase 1
2026-08-18
Enrollment closed, study ongoing
NCT05950165 A Study to Assess Safety and Efficacy of CHO-H01 as a Single Agent/Combined With… · Cho Pharma Inc. · Phase 1/2
2026-08-27
Trial status changed: Suspended → Active, Not Recruiting
NCT07166419 Anti-CD19/20/22 Chimeric Antigen Receptor T Cells (TriCAR19.20.22 T Cells) for the… · Ohio State University Comprehensive Cancer Center · Phase 1
2026-08-11
Recruitment opened
NCT07603479 JL19001 Injection Alone or in Combination With Standard Therapy in Patients With Advanced… · Jecho Biopharmaceuticals Co., Ltd. · Phase 1
2026-08-11
Enrollment closed, study ongoing
NCT05169515 A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Mosunetuzumab or… · Hoffmann-La Roche · Phase 1

New sponsor entrants, last 90 days sponsors with their first trial in this area

First postedTrialSponsorPhase
2026-08-13 NCT07763210 Lazarus: IT Therapy for ICANS Vanderbilt-Ingram Cancer Center new Phase 2
2026-08-06 NCT07750886 Sample Collection for Ongoing Research and Product Evaluation Study - Non-Hodgkin… Natera, Inc. new
2026-08-05 NCT07748364 Glofitamab in B-NHL Using Mid-Therapy Intratumoral Transcriptomics Joshua Brody new Phase 2
2026-07-28 NCT07730515 Clinical Study of XNW5004 Combined With CHOP/CHOEP in the Treatment of Untreated… Evopoint Biosciences Inc. new Phase 1/2
2026-07-22 NCT07721194 Primary Bone Mature B-Cell NHL in Children Centre Hospitalier Universitaire de Nice new
2026-07-20 NCT07713459 A Phase II Study to Evaluate the Efficacy of UF-KURE19 Cells in Patients With Relapsed or… Kure Cells, INC new Phase 2
2026-07-10 NCT07695896 Real-World Study of Bispecific Antibody in Relapsed or Refractory B-Cell Non-Hodgkin… Yanyan Liu new
2026-07-09 NCT07691606 A Study of ARC-02 in B-cell NHL Taiho Oncology, Inc. new Phase 1
2026-07-01 NCT07679919 BAFF CAR-T Cells (LMY-922) for Treatment of Refractory Hematologic Malignancies Luminary Therapeutics new Phase 1
2026-06-22 NCT07658352 A First-in-Human Study of HP-002 for Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma Shanghai Helioson Pharmaceutical Co., Ltd. new Phase 1/2

Active trials by phase

Early Phase 1
20
Phase 1
158
Phase 1/2
79
Phase 2
109
Phase 2/3
5
Phase 3
8
Phase 4
5
Not charted: 63 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 447

NCT IDTitleSponsorStatusUpdated
Phase 4
NCT06876649 A Master Protocol to Evaluate the Long-Term Safety of (LY3527727) Pirtobrutinib Eli Lilly and Company Recruiting 2026-03-02
NCT06876662 A Study of (LY3527727) Pirtobrutinib in Participants With Previously Treated Chronic… Eli Lilly and Company Recruiting 2026-03-02
NCT07016165 Ciprofloxacin vs Ceftazidime for Empirical Treatment of High-Risk Neutropenic Fever in… Gadjah Mada University Recruiting 2025-08-22
NCT05518383 B-cell Mature Non-Hodgkin's Lymphoma Treatment Protocol in Children and Adolescents 2021 Federal Research Institute of Pediatric Hematology, Oncology and Immunology Recruiting 2022-08-26
NCT06665737 Outcomes of Early and Late Administration G-CSF for Primary Prophylaxis in Non-Hodgkin's… Department of Medical Services Ministry of Public Health of Thailand Not Yet Recruiting 2025-01-28
Phase 3
NCT07188558 A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy Lyell Immunopharma, Inc. Recruiting 2026-08-04
NCT05645107 A Study to Evaluate Efficacy, Safety, and PK of XEMBIFY®+Standard Medical Treatment (SMT)… Grifols Therapeutics LLC Recruiting 2026-07-29
NCT07582432 A Clinical Trial to Evaluate Efficacy, Safety, and Pharmacokinetics of Gamunex in… Grifols Biologicals, LLC Recruiting 2026-05-12
NCT05171647 A Study Evaluating Efficacy and Safety of Mosunetuzumab in Combination With Polatuzumab… Hoffmann-La Roche Active, Not Recruiting 2026-08-05
NCT04002297 A Study to Investigate the Efficacy of Zanubrutinib Plus Rituximab Compared With… BeOne Medicines Active, Not Recruiting 2026-05-18
NCT06230224 A Trial to Learn How Effective and Safe Odronextamab is Compared to Standard of Care for… Regeneron Pharmaceuticals Active, Not Recruiting 2026-05-11
NCT03206671 Treatment Protocol of the NHL-BFM and the NOPHO Study Groups for Mature Aggressive B-cell… University Hospital Muenster Active, Not Recruiting 2026-04-30
NCT04459416 Managing Pain and Symptom Burden Caused by Chemotherapy in People With Myeloma or Lymphoma Memorial Sloan Kettering Cancer Center Active, Not Recruiting 2025-10-20
Phase 2/3
NCT07168980 Chemotherapy With Rituximab for Aggressive B-NHL in Children and Adolescents Children's Cancer Group, China Recruiting 2026-06-04
NCT07502118 NexCAR19 (Talikabtagene Autoleucel) in Relapsed/Refractory B-Cell Malignancies (NexCAR19) Health Institutes of Turkey Recruiting 2026-03-30
NCT05991388 A Global Study of Novel Agents in Paediatric and Adolescent Relapsed and Refractory… University of Birmingham Recruiting 2026-02-20
NCT03984448 Testing the Addition of a New Anti-cancer Drug, Venetoclax, to Usual Chemotherapy for… National Cancer Institute (NCI) Active, Not Recruiting 2026-08-04
NCT02405676 BNHL-2015 for Children or Adolescents in China Children's Cancer Group, China Active, Not Recruiting 2026-03-19
Phase 2
NCT06835530 A Combination of Rituximab and CC-99282 as Front-line Therapy for Older Frail Patients… Fondazione Italiana Linfomi - ETS Recruiting 2026-08-24
NCT04803201 Testing the Addition of Duvelisib or CC-486 to the Usual Treatment for Peripheral T-Cell… Alliance for Clinical Trials in Oncology Recruiting 2026-08-19
NCT04002947 Acalabrutinib With DA-EPOCH-R or R-CHOP for People With Untreated Diffuse Large B-cell… National Cancer Institute (NCI) Recruiting 2026-08-13
NCT06526793 Surovatamig (AZD0486) as Monotherapy in Participants With Relapsed/Refractory (R/R)… AstraZeneca Recruiting 2026-08-13
NCT06486051 A Study of Atlacabtagene Autoleucel CAR T-cells for Adults With Relapsed Large B-cell… Malaghan Institute of Medical Research Recruiting 2026-08-07
NCT04906096 Paxalisib (GDC-0084) In Recurrent Or Refractory PCNSL Lakshmi Nayak, MD Recruiting 2026-08-05
NCT02727803 Personalized NK Cell Therapy in CBT M.D. Anderson Cancer Center Recruiting 2026-07-30
See all 447 active Non-Hodgkin Lymphoma trials with filters →

Top sponsors by active trials in this area

National Cancer Institute (NCI) (28) · City of Hope Medical Center (26) · Baylor College of Medicine (10) · Mayo Clinic (10) · Memorial Sloan Kettering Cancer Center (10) · M.D. Anderson Cancer Center (9) · Ruijin Hospital (6) · AstraZeneca (5) · Fred Hutchinson Cancer Center (5) · St. Jude Children's Research Hospital (5)

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