Clinical Trial

Cardiovascular Reserve Evaluation in Survivors of Transplant, CREST Study

Active, Not Recruiting
View on ClinicalTrials.gov →
Summary
This study evaluates how well the heart, lungs, and muscles are working individually, and how these systems are working together in transplant survivors. Information collected in this study may help doctors to understand why hematopoietic stem cell transplant survivors are at higher risk for developing cardiovascular disease.
Protocol Amendment History 2 changes
notable Primary completion pushed: 2026-06-30 -> 2027-05-25 2026-08-15
minor Completion pushed: 2026-06-30 -> 2027-05-25 2026-08-15
Trial Details
NCT Number NCT04537871
Lead Sponsor City of Hope Medical Center
Collaborators: National Cancer Institute (NCI), National Heart, Lung, and Blood Institute (NHLBI)
Conditions Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Hematopoietic and Lymphoid Cell Neoplasm, Hodgkin Lymphoma, Myelodysplastic Syndrome, Non-Hodgkin Lymphoma, Plasma Cell Myeloma
Enrollment 350 participants
Start Date 2020-11-18
Primary Completion 2027-05-25 (estimated)
Study Completion 2027-05-25 (estimated)
Updated on ClinicalTrials.gov 2026-08-14