| Detected | Trial | Change |
|---|---|---|
| 2026-08-04 | NCT03412058 Identifying the Predictive Factors of Response to PD-1 or PD-L1 Antagonists |
critical Trial terminated |
| 2026-08-04 | NCT03412058 Identifying the Predictive Factors of Response to PD-1 or PD-L1 Antagonists |
critical Trial terminated: The study was terminated prematurely due to insufficient patient recruitment |
| 2026-08-04 | NCT03412058 Identifying the Predictive Factors of Response to PD-1 or PD-L1 Antagonists |
Enrollment reduced: 670 -> 152 participants |
| 2026-08-04 | NCT06680596 Detecting Tumor DNA in the Blood of HR+/HER2-low Metastatic Breast Cancer Patients to… |
Trial sites expanded: 34 -> 38 locations |
| 2026-08-04 | NCT03077776 Tracking Triple-negative Breast Cancer Evolution Through Therapy |
date change Completion pushed: 2026-05 -> 2026-09-30 |
| 2026-08-01 | NCT03246841 Investigation of Tumour Spectrum of Germline Mutations in Breast and Ovarian Cancer Genes. |
date change Primary completion pushed: 2025-09-30 -> 2026-12-30 |
| 2026-08-01 | NCT03246841 Investigation of Tumour Spectrum of Germline Mutations in Breast and Ovarian Cancer Genes. |
date change Completion pushed: 2025-12-31 -> 2026-12-31 |
| 2026-08-01 | NCT04747054 Study on the Efficacy of Treatment by Radiotherapy and Pembrolizumab in Newly Diagnosed… |
date change Primary completion pushed: 2025-10-01 -> 2026-10-01 |
| 2026-08-01 | NCT07106632 Optimising Adjuvant Chemotherapy Prescription in Young Patients With Hormone-dependent… |
Recruitment opened |
| 2026-07-25 | NCT05476796 Oxaliplatin ± Nivolumab in Combination With Trifluridine/Tipiracil or 5-fluorouracile in… |
overall status: Recruiting → Active, Not Recruiting |
| 2026-07-25 | NCT05476796 Oxaliplatin ± Nivolumab in Combination With Trifluridine/Tipiracil or 5-fluorouracile in… |
date change Primary completion pushed: 2026-01 -> 2026-12 |
| 2026-07-25 | NCT05476796 Oxaliplatin ± Nivolumab in Combination With Trifluridine/Tipiracil or 5-fluorouracile in… |
date change Completion moved earlier: 2027-01 -> 2026-12 |
| 2026-07-24 | NCT07120087 Evaluation of an Online Intervention to Educate Women at High Risk of Breast Cancer on… |
date change Primary completion pushed: 2026-06-19 -> 2026-12-31 |
| 2026-07-23 | NCT07340567 Personalizing Chemotherapy Selection After Surgery for Patients With Stage III Colorectal… |
overall status: Not Yet Recruiting → Active, Not Recruiting |
| 2026-07-22 | NCT07360743 Immunotherapy Without Chemotherapy for Advanced Lung Cancer Patients With High PD-L1… |
Trial sites expanded: 0 -> 4 locations |
| 2026-07-22 | NCT07241273 SPECT-CT Guided ELEctive Contralateral Neck Treatment in Lateralized Oropharyngeal Cancer |
date change Primary completion pushed: 2030-04 -> 2030-09 |
| 2026-07-22 | NCT07241273 SPECT-CT Guided ELEctive Contralateral Neck Treatment in Lateralized Oropharyngeal Cancer |
date change Completion pushed: 2031-04 -> 2031-09 |
| 2026-07-22 | NCT07230613 Neo-adjuvant Immunotherapy in Patients With Localized Melanoma |
Trial sites expanded: 1 -> 6 locations |
| 2026-07-19 | NCT07661927 Skipping Hormone Therapy in Low-Risk Early Breast Cancer |
Recruitment opened |
| First Posted | Trial | Phase | Status |
|---|---|---|---|
| 2026-08-04 | NCT07745296 Investigating Precision Medicine in the Adjuvant Setting in Biliary Tract Cancer | Phase 3 | Not Yet Recruiting |
| 2026-07-21 | NCT07717450 Rising ctDNA to Tailor Endocrine Therapy Switch in Patients With ER+/HER2- Metastatic… | Phase 3 | Not Yet Recruiting |
| NCT ID | Title | Condition | Status |
|---|---|---|---|
| Phase 3 | |||
| NCT06276465 | Treatment With Darolutamide +/- Radiation Therapy for Patients With a Castration… | Prostatic Cancer, Castration-Resistant | Recruiting |
| NCT06496581 | Standard of Care +/- 177Lu-PSMA-617 In de Novo mHSPC Patients With Poor PSA Response… | Prostate Cancer Metastatic | Recruiting |
| NCT04916613 | ADT +/- Darolutamide in de Novo Metastatic Prostate Cancer Patients With Vulnerable… | Prostate Cancer Metastatic | Recruiting |
| NCT05615818 | Personalized Medicine for Advanced Biliary Cancer Patients | Biliary Tract Neoplasms | Recruiting |
| NCT07237256 | Chemotherapy De-escalation in HR +, HER2-, Intermediate-risk Early Breast Cancer Treated… | Breast Cancer | Recruiting |
| NCT06606730 | Personalizing the Use of Pembrolizumab for Patients Who Have a Strong Response in Early… | Breast Cancers | Recruiting |
| NCT04747054 | Study on the Efficacy of Treatment by Radiotherapy and Pembrolizumab in Newly Diagnosed… | Squamous Cell Carcinoma of Head and Neck | Recruiting |
| NCT06625970 | Study Evaluating the Efficacy and Safety of Darolutamide and Stereotactic Dose Escalated… | High Risk Prostate Carcinoma | Recruiting |
| NCT07106632 | Optimising Adjuvant Chemotherapy Prescription in Young Patients With Hormone-dependent… | Early Breast Cancer | Recruiting |
| NCT01442246 | Evaluation of Adjuvant Hormonal Treatment for 24 Months After Radical Prostatectomy in… | Metastases | Active, Not Recruiting |
| NCT01957436 | A Phase III Study for Patients With Metastatic Hormone-naïve Prostate Cancer | Metastatic Prostate Cancer | Active, Not Recruiting |
| NCT03799835 | Atezolizumab Plus One-year BCG Bladder Instillation in BCG-naive High-risk Non-muscle… | Bladder Cancer | Active, Not Recruiting |
| NCT00470223 | Combined Chemotherapy With or Without Zoledronic Acid for Patients With Osteosarcoma | Sarcoma | Active, Not Recruiting |
| NCT04115007 | Prostate-cancer Treatment Using Stereotactic Radiotherapy for Oligometastases Ablation in… | Oligometastatic Hormone Sensitive Prostate Cancer | Active, Not Recruiting |
| NCT01952223 | A Phase III of Cabazitaxel and Pelvic Radiotherapy in Localized Prostate Cancer and… | Adenocarcinoma of Prostate | Active, Not Recruiting |
| NCT04181203 | Combined Apalutamide, Radiotherapy, and LHRH Agonist in Prostate Cancer Patients After… | Prostate Cancer | Active, Not Recruiting |
| NCT03774732 | PD-1 Inhibitor and Chemotherapy With Concurrent Irradiation at Varied Tumour Sites in… | Non Small Cell Lung Cancer | Active, Not Recruiting |
| NCT01376752 | Hyperthermic Intra-Peritoneal Chemotherapy (HIPEC) in Relapse Ovarian Cancer Treatment | Ovarian Epithelial Cancer Recurrent | Active, Not Recruiting |
| NCT07284394 | Liver-directed Chemotherapy After Surgery of Liver Metastases of Colorectal Cancer in… | Colorectal Adenocarcinoma Metastatic in the Liver | Not Yet Recruiting |
| NCT05078047 | Study Comparing the Standard Administration of IO Versus the Same IO Administered Each 3… | Lung Cancer Metastatic | Active, Not Recruiting |
| NCT05552001 | Safety and Efficacy Analysis of an Antibody Associated With a Chemotherapy for Patients… | Triple Negative Breast Cancer | Active, Not Recruiting |
| NCT07717450 | Rising ctDNA to Tailor Endocrine Therapy Switch in Patients With ER+/HER2- Metastatic… | Metastatic Invasive Breast Cancer | Not Yet Recruiting |
| NCT04158362 | Endocrine Therapy With Abemaciclib or Chemotherapy as Initial Metastatic Treatment in… | Cancer Metastatic | Active, Not Recruiting |
| NCT07340567 | Personalizing Chemotherapy Selection After Surgery for Patients With Stage III Colorectal… | Colorectal Cancer | Active, Not Recruiting |
| NCT07118800 | Study Evaluating Two Treatment Strategies for Rectal Cancer in Patients ≥75 Years Old | Locally Advanced Rectal Adenocarcinoma | Not Yet Recruiting |