69 active trials 44 recruiting 2 Phase 3 29 disease areas 17 changes in 30 days
8 trials changed in the last 30 days: 0 stopped, 6 with notable changes, 2 with minor changes only.
Primary completion pushed from Aug 2026 to Aug 2027
Also in this update: Completion pushed from Aug 2027 to Aug 2028
The Methodist Hospital Research InstitutePhase 1 NCT06566443 Registry history of NCT06566443 on ClinicalTrials.gov (opens the registry)
Updated
Primary completion pushed from Jun 1, 2026 to Jun 1, 2028
Also in this update: Completion pushed from Dec 1, 2027 to Dec 1, 2028
The Methodist Hospital Research InstitutePhase 1 NCT06833866 Registry history of NCT06833866 on ClinicalTrials.gov (opens the registry)
Updated
Primary completion pushed from Sep 30, 2026 to Sep 30, 2028
Also in this update: Recruitment opened; Completion pushed from Dec 31, 2026 to Dec 31, 2029
The Methodist Hospital Research InstitutePhase 1 NCT07060014 Registry history of NCT07060014 on ClinicalTrials.gov (opens the registry)
Updated
Primary completion pushed from Mar 14, 2027 to Dec 30, 2028
Also in this update: Primary endpoint(s) modified; Completion pushed from Sep 14, 2027 to Sep 30, 2029
The Methodist Hospital Research InstituteNot applicable NCT06286800 Registry history of NCT06286800 on ClinicalTrials.gov (opens the registry)
Updated
Primary endpoint(s) modified
The Methodist Hospital Research InstitutePhase 1/2 NCT07651319 Registry history of NCT07651319 on ClinicalTrials.gov (opens the registry)
Updated
Recruitment opened
The Methodist Hospital Research InstitutePhase 2 NCT07060001 Registry history of NCT07060001 on ClinicalTrials.gov (opens the registry)
Updated
Trial status changed: Recruiting → Enrolling by Invitation
Also in this update: Completion pushed from Oct 31, 2027 to Oct 31, 2028
The Methodist Hospital Research InstitutePhase 4 NCT05185505 Registry history of NCT05185505 on ClinicalTrials.gov (opens the registry)
Updated
Trial status changed: Enrolling by Invitation → Completed
Also in this update: Final enrollment: 5 participants (planned 50); Primary completion date changed from estimate of Jun 30, 2026 to Sep 30, 2025
The Methodist Hospital Research InstitutePhase 2 NCT05171335 Registry history of NCT05171335 on ClinicalTrials.gov (opens the registry)
Updated
| First posted | Trial | Phase | Status |
|---|---|---|---|
| 2026-09-15 | NCT07820358 Semaglutide, Weight Loss, and LNG-IUD for Conservative Treatment of Endometrial Atypical… | Phase 2 | Not Yet Recruiting |
| Phase 1 | 8 | |
| Phase 1/2 | 12 | |
| Phase 2 | 16 | |
| Phase 2/3 | 1 | |
| Phase 3 | 1 | |
| Phase 4 | 5 |
| NCT ID | Title | Condition | Status | Updated |
|---|---|---|---|---|
| Phase 4 | ||||
| NCT06511232 | Intraosseous Morphine Administration During Anterior Cruciate Ligament Reconstruction | Anterior Cruciate Ligament Tear | Recruiting | 2026-04-09 |
| NCT06384651 | Intraosseous vs. Intravenous Vancomycin Administration in Total Ankle Arthroplasty | Infections | Recruiting | 2025-01-24 |
| NCT05185505 | Atezolizumab and Bevacizumab Pre-Liver Transplantation for Patients With Hepatocellular… | Hepatocellular Carcinoma | Enrolling by Invitation | 2026-10-08 |
| NCT05831774 | IO Vancomycin in TSA | Shoulder Injuries | Active, Not Recruiting | 2025-09-22 |
| NCT04665310 | Evaluation of Anti-rejection Drug, Tacrolimus, in African-Americans With Kidney Transplant | Kidney Disease, End-Stage | Active, Not Recruiting | 2025-03-14 |
| Phase 3 | ||||
| NCT07290491 | Spiritual Care or Psychotherapy Versus Palliative Care Alone in Patients With… | Cancer | Recruiting | 2025-12-18 |
| Phase 2/3 | ||||
| NCT06748144 | IO Vancomycin Spine | Lumbar Fusion Surgery | Not Yet Recruiting | 2026-03-25 |
| Phase 2 | ||||
| NCT07060001 | Efficacy of Hypomethylating Agents vs. Intensive Chemotherapy in Acute Myeloid Leukemia… | Acute Myeloid Leukemia (AML) | Recruiting | 2026-10-08 |
| NCT06887218 | 5-Fluorouracil/Leucovorin (5FU/LV) in Combination With Regorafenib in Patients With… | Metastatic Colorectal Cancer (CRC) | Recruiting | 2026-10-07 |
| NCT07383649 | Trial to Study Anti- HCMV Therapy in Breast Cancer Patients With Progressive Intracranial… | Brain Cancer Metastatic | Recruiting | 2026-08-10 |
| NCT05511246 | Venous Ethanol for Ventricular Tachycardia | Ventricular Tachycardia | Recruiting | 2026-07-24 |
| NCT05660083 | Alpelisib/iNOS Inhibitor/Nab-paclitaxel in Patients With HER2 Negative Metaplastic Breast… | HER2-negative Breast Cancer | Recruiting | 2026-06-04 |
| NCT07042685 | Trial of 5-Fluorouracil (5FU)-Based Therapy in Combination With Fruquintinib in Patients… | Metastatic Colorectal Cancer (CRC) | Recruiting | 2026-04-09 |
| NCT07050771 | Comprehensive Multimodal Prehabilitation Alone or With Neoadjuvant Therapy Before Major… | Hepatopancreaticobiliary (HPB) Malignancy | Recruiting | 2026-03-12 |
| NCT05305924 | Fulvestrant+Abemaciclib With Run-In of Fulvestrant in Er-Positive, Her2-Negative… | ER-Positive Breast Cancer | Recruiting | 2026-01-28 |
| NCT04494724 | Clazakizumab vs. Placebo - COVID-19 Infection | COVID-19 Infection | Recruiting | 2020-07-31 |
| NCT07820358 | Semaglutide, Weight Loss, and LNG-IUD for Conservative Treatment of Endometrial Atypical… | Endometrial Atypical Hyperplasia | Not Yet Recruiting | 2026-10-01 |
| NCT03820141 | Durvalumab With Trastuzumab and Pertuzumab in HER2-Enriched Breast Cancer | Breast Cancer | Active, Not Recruiting | 2026-04-20 |
| NCT06751602 | Belumosudil for Abrogation of Interstitial Fibrosis and Tubular Atrophy Following Kidney… | Rejection Chronic Renal | Enrolling by Invitation | 2025-11-12 |
| NCT05241340 | Neoadjuvant Sasanlimab With Radiation as an in Situ Vaccine for Cisplatin-ineligible… | Urothelial Carcinoma Bladder | Active, Not Recruiting | 2025-10-24 |
| NCT03478215 | Mesenchymal Stromal Cells in Living Donor Kidney Transplantation | Renal Transplantation | Active, Not Recruiting | 2025-03-14 |
| NCT05285878 | Fingolimod for the Abrogation of Interstitial Fibrosis and Tubular Atrophy Following… | Interstitial Fibrosis | Enrolling by Invitation | 2025-03-14 |
| NCT04055623 | T-regulatory Cells in ALS | ALS (Amyotrophic Lateral Sclerosis) | Active, Not Recruiting | 2021-10-06 |
| Phase 1/2 | ||||
| NCT07651319 | Interleukine-2 (IL-2) Plus Semaglutide in Alzheimer's Disease | Alzheimer Dementia (AD) | Recruiting | 2026-09-23 |
| NCT07048314 | Stem Cells for Erectile Dysfunction Post RALP | Erectile Dysfunction | Recruiting | 2026-07-10 |
Breast Cancer (5) · Chronic Kidney Disease (4) · Prostate Cancer (4) · Stroke (3) · Alzheimer's Disease (2) · Bladder Cancer (2) · Colorectal Cancer (2) · Dementia (2) · Obesity (2) · Acute Myeloid Leukemia (AML) (1)